Vergangene Seminare seit 2016

Raum: Lecture hall Ort: MPI for Terrestrial Microbiology
The bacterial flagellar motor is a membrane-embedded rotary macromolecular machine that converts the electrochemical energy of the proton gradient into the mechanical energy of rotation. The knowledge about the bacterial motor is a source of inspiration for nanotechnology and one of the first steps towards making artificial motors on the same scale. Recent breakthrough electron cryotomography studies have revealed proteinaceous periplasmic structures adjacent to the stator (the powerhouse) of polar flagellar motors, which are essential for the stator assembly and function. The talk will showcase the cutting-edge research on the structure, composition, and function of the periplasmic scaffold in the polar bacterial flagellar motor of Helicobacter pylori. This microorganism displays high motility in the very viscous mucous layer of the stomach, which enables us to use H. pylori as a model system to study the polar motor specialised for locomotion in highly viscous fluids. The presented work will illustrate the advantages of an interdisciplinary approach combining biology and physics. The presentation will conclude with the discussion of the new paradigm for how the previously unseen accessory components control the function of the flagellar motor. [mehr]

How to catch a nematode if you were a mushroom

Microbiology Seminar Series

The predation strategy of Myxococcus xanthus

Microbiology Seminar Series

Why was a complement inhibitor used in the 2011 German EHEC outbreak?

SFB/Transregio TRR 174

IMPRS Selection Symposium

From stress to success: how actinobacteria exploit life without a cell wall

SFB/Transregio TRR 174

Learning from predatory bacteria: from `omics´ to molecular mechanisms

Microbiology Seminar Series

Coordination of cell wall homeostasis with cell division: Genes, suppressors and beyond

SFB/Transregio TRR 174

Microfluidic single-cell cultivation: Concept, application and challenges

Microbiology Seminar Series

Development of molecular tools for research on red and green algae

SFB 987 Mini-Symposium

Breaching the Barrier: Quantifying Antibiotic Permeability across Gram-negative Bacterial Membranes

SFB 987 Mini-Symposium

Kicking the"BolA" in Bacterial Survival and Virulence

SFB 987 Mini-Symposium

Mechanisms of microbiota-pathogen interactions

SFB 987 Mini-Symposium

Salmonella-microbiome interactions in the gut and their impact on transmission

Microbiology Seminar Series

Pseudomonas aeruginosa transcription profiling

SFB 987 Mini-Symposium

The bacterial stringent response in the context of root nodule symbiosis

SFB 987 Mini-Symposium

Disulfide bond formation underpins antimicrobial resistance in Enterobacteria

Microbiology Seminar Series

Bacterial "gap junctions" in cell-cell communication of multicellular cyanobacteria

SFB/Transregio TRR 174

Faculty of 1000 at Max Planck Institutes

Special seminar

Visualizing Bacterial Physiology at High Resolution using Single-Molecule Tracking and Lattice-Light Sheet Microscopy

Transcriptional regulators in the archaeon Sulfolobus acidocaldarius: homologies and differences with bacterial regulators

Microbiology Seminar Series

Powering LPS transport across the bacterial cell envelope with ABCs

Transregio TRR 174 Seminar

STUDIES OF SINGLE-MOLECULE DYNAMICS IN MICROORGANISMS

PhD Defense

Graduate Students Mini-Symposium II/2019

Graduate Students Mini-Symposium

Managing the bacterial chromosome

Transregio TRR 174 Seminar

Dynamics of bacterial biofilm predation

PhD Defense

From biofuels to biotherapeutics - Engineering metalloenzymes for a better future

Microbiology Seminar Series

Protecting the offspring – Linking developmental pathways of Aspergillus fumigatus to toxic compounds

SFB 987 Mini-Symposium

How to get published in Nature Communications and other Nature journals

Special seminar

Specific integration and regulation of the prokaryotic-type protein synthesis machinery in chloroplasts of plants

Microbiology Seminar Series

Synthetic genomics: from genetic parts to genomes

Transregio TRR 174 Seminar

Surfing in the storm: Revealing biochemical networks of Burkholderiales to deal with toxic compounds and heavy metals

Special seminar

Sulfur incorporation into tRNA: Unique mechanistic features and functions in bacteria

SFB 987 Mini-Symposium

Replication control of multiple chromosomes in bacteria

Transregio TRR 174 Seminar

Computational modeling of metabolism in a minimal cell

Special seminar

Mechanosensing in cell membranes

Special seminar

Mass spectrometric exploration of the proteotype

Microbiology Seminar Series

The evolution and functions of gut microbiota in bees

SFB 987 Mini-Symposium

Defining species in the microbial world

SFB 987 Mini-Symposium

Synthetic Gene-Metabolic Circuits for Bioproduction, Biosensing and Biocomputation

Special seminar

Microbial mediation of folivory

Special seminar

Self-organization of the bacterial cell division machinery

Microbiology Seminar Series

Salmonella diarrhea: mucus barriers, hydrogen-fueled growth and DNA transfer in the gut

Microbiology Seminar Series

Cryo-EM gets sweet: Molecular insight into glycosylation

Special seminar

Toward artificial cells: Engineering synthetic membranes, organelles, gene circuits and communication

Special seminar

The burden of inherited interfaces: evolution of self-assembly after gene duplication

Microbiology Seminar Series

The ParA/MinD family of ATPases make waves to position DNA, Cell Division, & Organelles in bacteria

Special seminar

"It-Ma(t)Ter(s)" Conference

This is a joint young researcher's conference organized between the MPI for Terrestrial Microbiology and our partner MPI for Marine Microbiology in Bremen. [mehr]

Unipolar growth of Brucella abortus in culture and inside host cells

Transregio TRR 174 Seminar

Understanding and exploiting bacterial lifestyles

Transregio TRR 174 Seminar

Pathogen effectors hitchhike the host ubiquitination pathway

SFB 987 Mini-Symposium

Towards synthetic life: Establishing a minimal segrosome for the rational design of biomimetic systems

PhD Defense

### Cancelled ###

Microbiology Seminar Series

To be announced

Transregio TRR 174 Seminar

Minimal metabolic engineering - getting the most bang for your buck

SFB 987 Mini-Symposium

Graduate Students Mini Symposium I/2019

Graduate Students Mini-Symposium

Organelle-like structures in Agrobacterium tumefaciens and Ralstonia eutropha

Transregio TRR 174 Seminar

A protein complex formed by Ustilago maydis effectors is essential for virulence (PhD Defense)

PhD Defense

A new facet of vitamin B12: gene regulation by a novel and widespread family of adenosylcobalamin-dependent photoreceptors in bacteria

SFB 987 Mini-Symposium

Salmonella persisters during infection

C A N C E L E D - SFB 987 Mini-Symposium

The ParC/ ParP system in the localization and segregation of chemotaxis signaling arrays in Vibrio cholerae and Vibrio parahaemolyticus (PhD Defense)

PhD Defense

Graduate Students Mini-Symposium VI/2018

Graduate Students Mini-Symposium

Understanding cell division and its regulation in the human pathogenic bacterium, Vibrio parahaemolyticus (PhD Defense)

PhD Defense

Frontiers in Microbiology 2018

Special seminar

Frontiers in Microbiology 2018

Special seminar

RocS drives chromosome segregation and nucleoid protection during cell division of Streptococcus pneumoniae

Transregio TRR 174 Seminar

Mechanisms of co-translational folding and assembly of proteins studied by ribosome profiling

SFB 987 Mini-Symposium

Darwin’s invertebrates: A transient anoxic microbial oasis

MPI Seminar

Structural and mechanistic insights into the guanine nucleotide exchange factor complex Mon1-Ccz1

SFB 987 Mini-Symposium

The networking of microbiomes across plant generations

SFB 987 Mini-Symposium

Methylotrophic methanogens everywhere - ecology and physiology of novel players in global methane cycling

SFB 987 Mini-Symposium

Structural insights into effector kinases from pathogenic gram-negative bacteria

SFB 987 Mini-Symposium

The role of M23 peptidases on cell division and cell shape in Vibrio parahaemolyticus

Graduate Students Mini-Symposium

Regulatory circuits controlling the glycine betaine synthesizing pathway in Bacillus subtilis

Graduate Students Mini-Symposium

Proteomics - a new tool for type II methanotroph research

Graduate Students Mini-Symposium

Graduate Students Mini-Symposium V/2018

Graduate Students Mini-Symposium

Heterogeneity of gene expression during biofilm formation in Escherichia coli

PhD Defense

Key proteins in the cell division of filamentous cyanobacteria

Transregio TRR 174 Seminar

Genomics of uncultivable bacteria deciphers multilayered symbiotic system in the termite gut

MPI Seminar

Establishing CO2 fixation pathways in Methylobacterium extorquens

Graduate Students Mini-Symposium

Evolution of a Non-natural Carboxylase for Synthetic Photorespiration

Graduate Students Mini-Symposium

Influence of cardiolipin on the function of bacterial chemoreceptors

Graduate Students Mini-Symposium

Determination of the substrate recognition by fumarate adding enzymes

Graduate Students Mini-Symposium

Graduate Students Mini-Symposium IV/2018

Graduate Students Mini-Symposium

Control of reactive intermediates in enzymes and enzyme complexes

PhD Defense

New techniques in ultra high throughput directed evolution screens

Special seminar

α-Ketoglutarate dependent dioxygenases - computational studies on reaction mechanisms

SFB 987 Sonderseminar

A CTP-binding protein links the ParABS chromosome segregation system to the bactofilin cytoskeleton in Myxococcus xanthus

Graduate Students Mini-Symposium

Shedding Light on CETCH: Linking synthetic carbon fixation pathways to the energy produced by light powered thylakoids

Graduate Students Mini-Symposium

Biofilm architectural breakdown in response to antibiotics facilitates community invasion

Graduate Students Mini-Symposium

Characterization of DNA interference by a minimal Type I CRISPR-Cas system

Graduate Students Mini-Symposium

Graduate Students Mini-Symposium III/2018

Graduate Students Mini-Symposium

Bacterial warfare: antibiotic production and resistance in co-existing Streptomycetes

SFB 987 Mini-Symposium

Mechanosensing with type IV pili in Pseudomonas aeruginosa

SFB 987 Mini-Symposium

High-throughput interaction profiling in bacteria

Microbiology Seminar Series

Unraveling the function of a stress sentinel in the bacterial envelope

Transregio TRR 174 Seminar

Bacterial chromosome organization

Microbiology Seminar Series

A circuitous route to mitochondrial acylation in regulation of oxidative phosphorylation

SFB 987 Mercator-Fellow Seminar

Chemotaxis of Escherichia coli to compounds present in human gut (PhD defense)

PhD Defense

Mechanisms of transmembrane signaling by sensors of two-component system

SFB 987 Mini-Symposium

Finally, archaea get their CRISPR-cas toolbox

SFB 987 Mini-Symposium

Synthetic noise control in eukaryotic gene expression and signal transduction (PhD Defense)

PhD Defense

Natural products in microbial predator-prey interactions

MPI Seminar

Viruses of Archaea: what we can learn from them

Special seminar

Exploring molecular landscapes inside cells with in situ cryo-electron tomography

Microbiology Seminar Series

High-resolution whole genome mapping of Sister Chromatid Contacts (Hi-SC2) in Vibrio cholerae

Transregio TRR 174 Seminar

Bacterial ribosome heterogeneity: Novel aspects of selective translation

SFB 987 Mini-Symposium

Activation of the bacterial stringent response

SFB 987 Mini-Symposium

Molecular tricks of methanogenic archaea

MPI Seminar

Physiology and cell biology of bacterial epithelia

Transregio TRR 174 Seminar

Symbioses as sources of evolutionary innovation in insects

Special seminar

From boom to bust - the dynamics of bacterial adaptation under prolonged resource limitation

SFB 987 Mini-Symposium

Unlocking the potential of synthetic biology - from DNA foundries to cell-free prototyping

SFB 987 Mini-Symposium

Genetic circuit design

SFB 987 Mini-Symposium

c-di-AMP signaling in Staphylococcus aureus: What makes, breaks and binds it

SFB 987 Mini-Symposium

Deadly conversation between bacteria

SFB 987 Mini-Symposium

Adaptive genome evolution in the vascular wilt pathogen Verticillium

MPI Seminar

D-Amino acids shape the environmental microbial biodiversity

MPI Seminar

Self-assembly of a bacterial nanomachine: Flagella grow through an injection-diffusion mechanism

SFB 987 Mini-Symposium

C A N C E L L E D Chemical interaction between iron-cycling microbes: news from the chat room

SFB 987 Mini-Symposium

Divorcing chromosomes still need rings: the role of an ancestral SMC protein in bacterial chromosome organisation and segregation

Transregio TRR 174 Seminar

Characterization of a Serine/Threonine kinase in Vibrio parahaemolyticus

Graduate Students Mini-Symposium

Architecture of Vibrio parahaemolyticus swarm-colonies

Graduate Students Mini-Symposium

Studies on catalytic mechanism of [Fe]-hydrogenase from methanogenic archaea

Graduate Students Mini-Symposium

Graduate Students Mini-Symposium II/2018

Microbiology Seminar Series

*** CANCELED *** Visualizing and quantifying the selfish uptake of high molecular weight polysaccharides by marine bacteria

SFB 987 Mini-Symposium

Microbe-Electrode-Interactions

SFB 987 Mini-Symposium

The design and realization of synthetic pathways for the fixation of carbon dioxide in vitro (PhD defence)

PhD Defense

The seminar will start later (on 15:00 h) due to a snow storm in Munich "Architecture and biogenesis of an antibacterial speargun: the type VI secretion system"

Transregio TRR 174 Seminar

How proteins control electrons: Protons

MPI Seminar

Regulation of peptidoglycan biosynthesis in Hyphomonas neptunium

Graduate Students Mini-Symposium

Biochemistry of the key spatial regulators MipZ and PopZ in Caulobacter crescentus

Graduate Students Mini-Symposium

Shining light on the structural features of DNA repair in the PCSf

Graduate Students Mini-Symposium

Graduate Students Mini-Symposium I/2018

Microbiology Seminar Series

Dormancy or growth under deep starvation conditions & Observing antimicrobial activities in single cells

SFB/Transregio TRR 174

SFB Mini Symposium

Microbiology Seminar Series

How to distribute multiple chromosomes along the hyphal cell?

SFB/Transregio TRR 174

Structure-function analysis of Cmu1, the secreted chorismate mutase from Ustilago maydis (PhD defense)

PhD Defense

Using images to understand structure, function and dynamics of Type VI secretion systems

Microbiology Seminar Series

SFB Mini Symposium

Microbiology Seminar Series

Structure, function, assembly and engineering of bacterial microcompartments

Microbiology Seminar Series

Elucidating the lipopolysaccharide biosynthetic pathway in Myxococcus xanthus

Graduate Students Mini-Symposium

Structural variation of type I-F CRISPR RNA guided DNA surveillance

Graduate Students Mini-Symposium

Graduate Students Mini-Symposium VI/2017

Graduate Students Mini-Symposium

SFB Mini Symposium

Microbiology Seminar Series

Northern wetlands: a world of unique microbes with difficult characters

SFB Mini Symposium

Cell-wall remodelling drives engulfment during sporulation in Bacillus subtilis

Microbiology Seminar Series

Solving the kinetochore structure of Schizosaccharomyces pombe with single molecules localization microscopy

Graduate Students Mini-Symposium

About the creation and isolation of switching metabolic enzymes

Graduate Students Mini-Symposium

Metatranscriptomics reveals drainage effects on paddy soil microbiome across all three domains of life

Graduate Students Mini-Symposium

Chemotaxis towards autoinducer 2 mediates intra- and interspecies behaviors of Escherichia coli

Graduate Students Mini-Symposium

C A N C E L L E D - Postponed to 20.11.2017

Microbiology Seminar Series

SFB Mini Symposium

Microbiology Seminar Series

All you never wanted to know about cooperative 2-electron transitions but should definitely dare to ask

Microbiology Seminar Series

SFB Mini Symposium

Microbiology Seminar Series

Rhodopsins - the green light sensing component of the fungal eye

SFB Mini Symposium

In-House Career Day

Effector proteins from the rice blast fungus Magnaporthe oryzae provide novel insight into plant-pathogen interactions

Microbiology Seminar Series

Lantibiotic resistance in the human pathogen Streptococcus agalactiae

Microbiology Seminar Series

Redox-sensing mechanisms under infection conditions in Staphylococcus aureus

SFB Mini Symposium

SR1, the first dual-function sRNA from Bacillus subtilis. Base-pairing and peptide functions

SFB Mini Symposium

Plant developmental rewiring during the AM symbiosis

SFB Mini Symposium

Deviation from the norm: eukaryotic microbes with two kinds of nuclei and alternative genetic codes

Special seminar

The beauvericin cluster in Fusarium fujikuroi is controlled by a network of pathway-specific and global regulators

Microbiology Seminar Series: SFB Mini Symposium

Pseudomonas aeruginosa lifestyles, bacterial warfare and novel antimicrobials

Microbiology Seminar Series: SFB Mini Symposium

The hidden cost of enzyme catalysis

Microbiology Seminar Series

Establishing M. xanthus cell polarity

Graduate Students Mini-Symposium

Robust Population control in Synthetic Communities

Graduate Students Mini-Symposium

Graduate Students Mini Symposium IV/2017

Graduate Students Mini-Symposium

Tool engineering for synthetic microbial consortia for metabolic engineering

Graduate Students Mini-Symposium

Seeking intersections of microbiology, fluid mechanics, and physical chemistry

Special seminar
In this talk I describe various problems involving the intersections of fluid mechanics, bacterial biofilms and physical chemistry. I first highlight our studies of the influence of fluid motion on surface-attached bacteria and biofilms, where we identify and characterize upstream migration of surface-attached bacteria in a flow. Second, I highlight the influence of flow on quorum sensing, which refers to bacterial communication and collective behavior regulated by secreted chemicals. Our results suggest that bacterial colonization and biofilm development under flow can lead to heterogeneous QS activation, which promotes diversity in the genetic programs that bacteria enact. As a consequence, genetically identical bacteria exhibit different behaviours at particular regions and at particular times under flow. Finally, I describe an out-of-equilibrium consequence of concentration gradients, which, perhaps surprisingly, allow movement of particles (e.g. vesicles, DNA) in simple geometries. In particular, with salt gradients, via a mechanism referred to as diffusiophoresis, we can remove particles from dead-end pores or deliver particles into such pores. We explore the phenomenon using experiments and modeling. We close by posing the question if there might be broader consequences of these out-of-equilibrium physical chemistry ideas in biological contexts. [mehr]

Synthesis, import and export of ectoines

Graduate Students Mini-Symposium

Engineering of CO2 fixing reaction cascades to synthesize a diverse library of polyketide extender units

Graduate Students Mini-Symposium

Dynamic biofilm architecture confers individual and collective mechanisms of phage protection

Graduate Students Mini-Symposium

Towards biomimetic cell division: In vitro reconstitution of segregation

Graduate Students Mini-Symposium

Adhesins in Candida glabrata

Graduate Students Mini-Symposium

Graduate Students Mini Symposium III/2017

Graduate Students Mini-Symposium

Eyes of blue: Bacterial photoreceptors with multiple sensing and output functions

Microbiology Seminar Series: SFB Mini Symposium

Light and the life of bacteria - examples from Amsterdam

Microbiology Seminar Series: SFB Mini Symposium

Cell-states-dependent changes in cellular K+ determines protein activity in Escherichia coli

Graduate Students Mini-Symposium

Bacterial chemotaxis towards compounds in the gut

Graduate Students Mini-Symposium

Diversification of gene expression in Escherichia coli biofilms

Graduate Students Mini-Symposium

Functional characterization of a protein complex formed by four Ustilago maydis effectors essential for virulence

Graduate Students Mini-Symposium

Graduate Students Mini Symposium II/2017

Graduate Students Mini-Symposium

Effect of the environmental temperature on gene expression and motility system of E. coli¤

Graduate Students Mini-Symposium

The development of synthetic CO2 fixation pathways

Graduate Students Mini-Symposium

Coupling chemosensory array formation and localization

Graduate Students Mini-Symposium

Regulation of type IV pili asymmetry in Myxococcus xanthus¤

Graduate Students Mini-Symposium

Graduate Students Mini Symposium I/2017

Graduate Students Mini-Symposium

Noise control in signaling pathways

Graduate Students Mini-Symposium

Microbial symbionts of leaf-cutting ants (Atta and Acromyrmex)

Microbiology Seminar Series
Leaf-cutting ants harvest substantial amounts of leaf material to cultivate a specialized fungus for food (Leucoagaricus). This complex symbiosis includes at least four coevolved organisms: the farming ants, their fungal crop, a specialized mycoparasite of the ant’s fungal gardens (Escovopsis), and actinomycete bacteria (Pseudonocardia) that the ants culture on their bodies to obtain antibiotics against the parasites. We described an additional symbiosis with Nitrogen-fixing bacteria that colonize the fungus gardens and contribute to supplement the ants’ nutrition. Our present research efforts in Costa Rica focus on potential biotechnological applications of the ants’ microbial symbionts, including bioprospecting for new antibiotics and developing microbial-based biocontrol strategies. [mehr]

Metabolite cross-feeding in synthetic microbial communities: from ecology to biotechnological applications

Microbiology Seminar Series: SFB Mini Symposium

Drivers of assembly and coexistence in communities of arbuscular mycorrhizal fungi - the scale matters!

Microbiology Seminar Series: SFB Mini Symposium
Arbuscular mycorrhizal (AM) fungi are asexual, obligately symbiotic fungi with unique morphology and genomic structure, which occupy a dual niche, that is, the soil and the host root. Consequently, the direct adoption of models for community assembly developed for other organism groups is not evident. Based on recent studies using high throughput molecular methods and their findings, I will give an overview on the factors driving AM fungal community assembly at different scales. By synthesizing these findings, I will show how modern coexistence and assembly theory can be adapted to arbuscular mycorrhizal fungi and that hierarchical spatial structure of arbuscular mycorrhizal fungal communities should be explicitly taken into account in future studies. This conceptual framework developed for arbuscular mycorrhizal fungi is also adaptable for other host-associated microbial communities. [mehr]

Bacterial Modern Mass Spectrometric Methods in Life Science Research

Microbiology Seminar Series: SFB Mini Symposium

From commensalism to pathogenicity: stages of Candida albicans infections

Microbiology Seminar Series

Functional characterization of the Ustilago maydis virulence gene scp2 (PhD defense)

PhD Defense

Ploidy in prokaryotes: On the seldom cases of monoploidy and the many evolutionary advantages of polyploidy

SFB Mini Symposium

Bacterial small RNAs in regulatory circuits: interplay with transcription factors and mechanistic insights

SFB Mini Symposium

2nd Career Day

Special seminar
9:15 to 9:20Organizers of the 2nd Career DayWelcome9:20 to 9:55Dr. Thomas BühlerSenior Manager Analytical Services Quality - Microbiology (CSL Behring. Marburg, Germany)9:55 to 10:30Dr. Valeria GrassoPlant Pathologist (Syngenta Crop Protection AG. Stein, Switzerland)10:30 to 11:05Dr.-Ing. Ute DechertUnit Head Organisation & Processes (Brain AG. Zwingenberg, Germany)11:20 to 11:55Dr. Kerstin Lassak Trainee Patent Attorney (V.O. Patents & Trademarks. Munich, Germany)11:55 to 12:30Patricia Krause Senior Account Specialist Inhouse Services (Randstad. Marburg, Germany)13:30 to 14:05Dr. Carol Bacchus Vice President & Publishing Director, Research (Wiley-VCH Verlag GmbH & Co. KGaA. Weinheim, Germany)14:05 to 14:40Aileen D’Oria Recruiter - Talent Acquisition EMEA (Thermo Fisher Scientific, Darmstadt, Germany)14:55 to 15:30Thomas Glaeser Senior Recruiter EMEA (Leica Microsystems CMS GmbH. Wetzlar, Germany)15:30 to 16:05Dr. Tomasz Neiner Change Control Specialist (Abbott. Wiesbaden, Germany)16:05 to 16:15Concluding remarks [mehr]

Inverse toeprinting - A new, high-throughput method for identifying and characterizing ribosome arresting peptides

SFB Mini Symposium

Signal transduction by reversible protein phosphorylation in the third domain of life

SFB Mini Symposium

Last but not least – Late cell division proteins in Caulobacter crescentus (PhD defense)

PhD Defense

Sex pheromones and conjugation in gram-positive bacteria

SFB Mini Symposium

Sweets for my sweet: Carbohydrate transport and its regulation in Sulfolobus acidocaldarius (PhD defense)

PhD Defense

Deconstructing cell-size control into physiological modules in E. coli

Special seminar

Mechanisms and regulation of bacterial cell wall growth

How are Fe-S cofactors and proteins assembled in plant cells?: Focus on the late steps of the maturation process in organelles

Skin Microbial Endocrinology: When host neurohormones control bacterial homeostasis

Assembly and mechanism of respiratory complex I

SFB Mini Symposium

Structure of mitochondrial complex I

SFB Mini Symposium

Regulation of phototaxis in cyanobacteria and how a small cell can detect the direction of light

SFB Mini Symposium

Super complex formation of the denitirification respirasome of Pseudomonas aeruginosa

SFB Mini Symposium

Metabolic lifestyle and energy conservation tricks of giant, symbiotic bacteria – the special case of Epulopiscium

Special seminar

The physical ecology of (marine) microbes

Pan-archaeal analysis of C/D box sRNA biogenesis and methylation targets (PhD Defense)

PhD Defense

Key microbial players for the bioremediation of petroleum hydrocarbons

Special seminar

Mechanistic and evolutionary aspects of gene expression noise in yeast

Bacteria cell shape memory under mechanical stress: Residual strains regulate rod-like cell shape in bacteria

Special seminar
Transmembrane chemoreceptors are central components in the sensory system that mediates bacterial chemotaxis. Like many transmembrane proteins, these receptors are fully active only if inserted in a lipid bilayer. This requirement presents a challenge for in vitro analysis by many biochemical and structural techniques. The challenge is met by Nanodiscs, soluble, nanoscale (~10 nm diameter) particles of lipid bilayer surrounded by an annulus of amphipathic protein into which transmembrane proteins can be incorporated. Using Nanodiscs, we documented that chemoreceptor dimers bend at a specific locus along their 300 Å long axis, discovered that conformational differences between chemoreceptor signalling states were differential propensities of receptor helices to become momentarily unstructured, and determined that chemoreceptor signalling complexes activate and control the chemotaxis histidine kinase by altering its catalytic rate constant. [mehr]

Comprehensive analysis of peptidoglycan hydrolases in Caulobacter crescentus (PhD Defense)

PhD Defense

Bacterial-fungal interactions in decaying wood: diversity and contribution to biogeochemical cycles

Special seminar

Characterization of the division apparatus in the budding bacterium Hyphomonas neptunium (PhD defense)

PhD Defense

Characterization of RomX and RomY, two novel motility regulators in Myxococcus xanthus

Graduate Students Mini-Symposium

Control of cell division during development of Myxococcus xanthus

Graduate Students Mini-Symposium

Structure-function analysis of Cmu1, a secreted chorismate mutase in Ustilago maydis

Graduate Students Mini-Symposium

The effector protein Ten1 of Ustilago maydis

Graduate Students Mini-Symposium

Insights into the small RNA interactome of Sulfolobus acidocaldarius

Graduate Students Mini-Symposium

Physicochemical conditions and microbial community structure in the guts of lignocellulose feeding cockroaches

Graduate Students Mini-Symposium

Microbial interactions from a molecular and evolutionary perspective

SFB Mini Symposium

The Integron: Adaptation on demand

SFB Mini Symposium

Sugar influx sensing by the phosphotransferase system of Escherichia coli

Graduate Students Mini-Symposium

Structure and biochemical studies on biosynthesis of the [Fe]-hydrogenase cofactor

Graduate Students Mini-Symposium

Genomics-enabled natural product discovery

Natural products have been, without question, the most prolific source of all medicines, especially antibiotics. Genome sequencing has revealed that our knowledge of natural product structure and function is astonishingly incomplete. Therefore, exploration of uncharted natural product chemical space will undoubtedly lead to improved, and entirely new, medicines. Against this backdrop, our group focuses on elucidating the biosynthesis, structure, and function of natural products. This talk will highlight our recent advances in genomics-enabled natural product discovery while covering a few case studies in enzymatic biosynthesis that could be exploited to introduce new drug leads. [mehr]

Understanding activation bacterial promoters

SFB Mini Symposium

Global reprogramming of the Yersinia pseudotuberculosis transcriptional landscape in response to temperature and host signals

SFB Mini Symposium

Oxymonads – eukaryotes without mitochondrion

Mitochondrion is a key evolutionary inventions specific to the eukaryotic cell. Oxymonads remained as one of a few eukaryotic groups, where no mitochondrion has been revealed so far. We have performed detailed genomic and transcriptomic study of oxymonad Monocercomonoides sp., which demonstrates the absence of mitochondrial hallmark proteins. The most striking is the absence of canonical mitochondrial protein import machinery and the substitution of mitochondrial iron sulphur cluster biosynthetic pathway (ISC) by the sulphur mobilization system (SUF). We conclude that Monocercomonoides represents the first report of amitochondriate eukaryote demonstrating the fact that under some circumstances eukaryotes may entirely loose mitochondrion. [mehr]

From ancient lipids to synthetic life

The function of the cell membrane as a barrier and a matrix for biochemical activity relies on the properties imparted by lipids. In eukaryotes, sterols are crucial for modulating the molecular order of membranes. Sterol ordering provides the basis for membrane lateral segregation and promotes a fluid, mechanically robust plasma membrane. How do organisms that lack sterols determine membrane order? Hopanoids are ancient bacterial membrane lipids that have been proposed as putative sterol surrogates. We now explore the role of hopanoids, their effect on membranes in Methylobacterium extorquens and reflect on the path to building functional synthetic membranes. [mehr]

Linking metabolic and cell cycle regulation

The cell division cycle consists of a sequence of processes whose specific demands for biosynthetic precursors and energy place dynamic requirements on metabolism. However, little is known about how metabolic fluxes are coordinated with the cell cycle. I will present our recent findings that over half of all measured metabolites change significantly through the cell division cycle. We find that the cyclin-dependent kinase Cdk1, a major cell cycle regulator, also controls carbon metabolism. Trehalose utilization fuels anabolic processes required to reliably complete cell division. This demonstrates how cell cycle regulation can entrain carbon metabolism to dynamically fuel biosynthesis during proliferation. [mehr]

Together we are stronger: adaptive benefits drive a division of metabolic labour in bacteria

SFB Mini Symposium

Sensing and responding: Terrein production in Aspergillus terreus

SFB Mini Symposium

Bacterial shapeshifting: Escherichia coli differentiation during urinary tract infection

Urinary tract infections are caused primarily by uropathogenic strains of Escherichia coli (UPEC). UPEC is known to transition through a series of distinct infection stages, displaying reversible morphological differentiation along the way. Initial steps involve bladder invasion by rod-shaped bacteria to establish intracellular bacterial communities consisting of coccoid cells. Subsequently, during exit from infected cells, UPEC regain their rod-shape and in some cases even form large filaments. Using a flow-chamber based tissue culture infection model we have studied UPEC gene expression during the course of infection. Our results reveal a novel SOS-independent mechanism of reversible cell-division control. [mehr]

Cell wall stress sensing in the Gram-negative pathogen Vibrio cholerae

Cell wall adhesins in fungal pathogens: A sticky business

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