The LOEWE program is an excellence initiative of the state of Hesse to promote excellent research at Hessian universities and other research institutions. SYNMIKRO, the LOEWE Center for Synthetic Microbiology, was founded in 2010 as a cooperation center between Philipps University Marburg and the Max Planck Institute for Terrestrial Microbiology. To this end, more than 50 million euros in funding was received from 2010 to 2018. Since then, the center has grown steadily and has become a center of attraction for young and more experienced scientists from all over the world. In SYNMIKRO, Biologists, biochemists, physicists, mathematicians, bioinformaticians and bioethicists work together in - the research collaboration that is unique for Germany offers completely new opportunities to expand our understanding of the molecular basis and potential uses of microorganisms and to open up new applications. The Marburg researchers aim to design synthetic cells with tailored properties from standardized building blocks. These cells could be used, for example, to produce new drugs, chemicals, biofuels and food additives efficiently, cost-effectively and in an environmentally compatible manner.