Microbial Metalloenzymes

Dr. Johannes Rebelein

Research Area

Metalloenzymes encompass the evolutionary oldest and most important classes of enzymes. We characterize and engineer metalloenzymes to elucidate the underlaying principals and mechanisms of metalloenzyme catalysis. The group focuses on the activation of nitrogen (N2) and carbon dioxide (CO2) by the enzyme nitrogenase. Harnessing these insights, we engineer metalloenzymes to develop improved catalysts for the production of bulk chemicals, including fertilizer (NH3), hydrocarbons (C2H4, C3H8, C4H10) and hydrogen (H2). The long-term goal is to develop novel metabolic pathways using these unique reactivities.

We are currently looking for postdocs, PhD students, and TAs to start as soon as July 2020. [more]

 

 



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