Publications of Roland Lill

Molik, S.; Lill, R.: Role of mitosomes in cellular iron-sulfur protein biogenesis. Journal of Endocytobiosis and Cell Research 23, pp. 77 - 85 (2012)

Netz, D. J. A.; Stith, C. M.; Stumpfig, M.; Kopf, G.; Vogel, D.; Genau, H. M.; Stodola, J. L.; Lill, R.; Burgers, P. M. J.; Pierik, A. J.: Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes. Nature Chemical Biology 8 (1), pp. 125 - 132 (2012)

Mühlenhoff, U...; Richter, N.; Pines, O.; Pierik, A.J.; Lill, R.: Specialized Function of Yeast Isa1 and Isa2 Proteins in the Maturation of Mitochondrial [4Fe-4S] Proteins. The Journal of Biological Chemistry 286 (48), pp. 41205 - 41216 (2011)

Navarro-Sastre, A.; Tort, F.; Stehling, O.; Uzarska, M. A.; Arranz, J. A.; del Toro, M.; Labayru, M. T.; Landa, J.; Font, A.; Garcia-Villoria, J. et al.; Merinero, B.; Ugarte, M.; Gutierrez-Solana, L. G.; Campistol, J.; Garcia-Cazorla, A.; Vaquerizo, J.; Riudor, E.; Briones, P.; Elpeleg, O.; Ribes, A.; Lill, R.: A Fatal Mitochondrial Disease Is Associated with Defective NFU1 Function in the Maturation of a Subset of Mitochondrial Fe-S Proteins. American Journal of Human Genetics 89 (5), pp. 656 - 667 (2011)

Ozeir, M.; Mühlenhoff, U.; Webert, H.; Lill, R.; Fontecave, M.; Pierrel, F.: Coenzyme Q Biosynthesis: Coq6 Is Required for the C5-Hydroxylation Reaction and Substrate Analogs Rescue Coq6 Deficiency. Chemistry & Biology 18 (9), pp. 1134 - 1142 (2011)

Mühlenhoff, U.; Molik, S.; Godoy, J. R.; Uzarska, M. A.; Richter, N.; Seubert, A.; Zhang, Y.; Stubbe, J.; Pierrel, F.; Herrero, E. et al.; Lillig, C. H.; Lill, R.: Cytosolic Monothiol Glutaredoxins Function in Intracellular Iron Sensing and Trafficking via Their Bound Iron-Sulfur Cluster. Cell Metabolism 12 (4), pp. 373 - 385 (2010)

Netz, D. J. A.; Stumpfig, M.; Dore, C.; Muhlenhoff, U.; Pierik, A. J.; Lill, R.: Tah18 transfers electrons to Dre2 in cytosolic iron-sulfur protein biogenesis. Nature Chemical Biology 6 (10), pp. 758 - 765 (2010)

Sheftel, A. D.; Stehling, O.; Pierik, A. J.; Elsasser, H. P.; Muhlenhoff, U.; Webert, H.; Hobler, A.; Hannemann, F.; Bernhardt, R.; Lill, R.: Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis. Proceedings of the National Academy of Sciences of the United States of America 107 (26), pp. 11775 - 11780 (2010)

Sheftel, A.; Stehling, O.; Lill, R.: Iron-sulfur proteins in health and disease. Trends in Endocrinology and Metabolism 21 (5), pp. 302 - 314 (2010)

Albrecht, A. G.; Netz, D. J. A.; Miethke, M.; Pierik, A. J.; Burghaus, O.; Peuckert, F.; Lill, R.; Marahiel, M. A.: SufU Is an Essential Iron-Sulfur Cluster Scaffold Protein in Bacillus subtilis. Journal of Bacteriology 192 (6), pp. 1643 - 1651 (2010)

Ihrig, J.; Hausmann, A.; Hain, A.; Richter, N.; Hamza, I.; Lill, R.; Muhlenhoff, U.: Iron Regulation through the Back Door: Iron-Dependent Metabolite Levels Contribute to Transcriptional Adaptation to Iron Deprivation in Saccharomyces cerevisiae. Eukaryotic Cell 9 (3), pp. 460 - 471 (2010)

Lill, R.: Function and biogenesis of iron–sulphur proteins. Nature 460, pp. 831 - 838 (2009)

Lillig, C. H.; Lill, R.: Lights on iron-sulfur clusters. Chemistry & Biology 16, pp. 1213 - 1214 (2009)

Naamati, A.; Regev-Rudzki, N.; Galperin, S.; Lill, R.; Pines, O.: Dual targeting of Nfs1 and discovery of its novel processing enzyme, Icp55. Journal of Bacteriological Chemistry 284 (44), pp. 30200 - 30208 (2009)

Sheftel, A. D.; Lill, R.: The power plant of the cell is also a smithy: The emerging role of mitochondria in cellular iron homeostasis. Annals of Medicine 41, pp. 82 - 99 (2009)

Sheftel, A. D.; Stehling, O.; Pierik, A. J.; Netz, D. J.; Kerscher, S.; Elsässer, H.-P.; Wittig, I.; Balk, J.; Brandt, U.; Lill, R.: Human Ind1, an Iron-Sulfur Cluster Assembly Factor for Respiratory Complex I. Molecular and Cellular Biology 29 (22), pp. 6059 - 6073 (2009)

Stehling, O.; Sheftel, A. D.; Lill, R.: Controlled expression of iron-sulfur cluster assembly components for respiratory chain complexes in mammalian cells. Methods in Enzymology 456, pp. 209 - 231 (2009)

Urzica, E.; Pierik, A. J.; Mühlenhoff, U.; Lill, R.: Crucial Role of Conserved Cysteine Residues in the Assembly of Two Iron-Sulfur Clusters on the CIA Protein Nar1. Biochemistry 48, pp. 4946 - 4958 (2009)

Boyd, J. M.; Pierik, A. J.; Netz, D. J. A.; Lill, R.; Downs, D. M.: Bacterial ApbC can bind and effectively transfer iron-sulfur clusters. Biochemistry 47, pp. 8195 - 8202 (2008)

Bych, K.; Kerscher, S.; Netz, D. J. A.; Pierik, A. J.; Zwicker, K.; Huynen, M. A...; Lill, R.; Brandt, U.; Balk, J.: The iron-sulphur protein Ind1 is required for effective complex I assembly. The EMBO Journal 27, pp. 1736 - 1746 (2008)