Publications of Georg K. A. Hochberg

Sendker, F. L.; Lo, Y. K.; Heimerl, T.; Bohn, S.; Persson, L. J.; Mais, C.-N.; Sadowska, W.; Paczia, N.; Nußbaum, E.; del Carmen Sánchez Olmos, M. et al.; Forchhammer, K.; Schindler, D.; Erb, T. J.; Benesch, J. L. P.; Marklund, E. G.; Bange, G.; Schuller, J. M.; Hochberg, G. K. A.: Emergence of fractal geometries in the evolution of a metabolic enzyme. Nature (2024)

Bozhüyük, K. A. J.; Präve, L.; Kegler, C.; Schenk, L.; Kaiser, S.; Schelhas, C. S.; Shi, Y.-N.; Kuttenlochner, W.; Schreiber, M.; Kandler, J. et al.; Alanjary, M.; Mohiuddin, T. M.; Groll, M.; Hochberg, G. K. A.; Bode, H. B.: Evolution-inspired engineering of nonribosomal peptide synthetases. Science 383 (6689), eadg4320 (2024)

Addison, H. G.; Glatter, T.; Hochberg, G. K. A.; Rebelein, J. G.: Two distinct ferredoxins are essential for nitrogen fixation by the iron nitrogenase in Rhodobacter capsulatus. mBio 15 (3), e0331423 (2024)

Jakob, S.; Steinchen, W.; Hanßmann, J.; Rosum, J.; Langenfeld, K.; Osorio-Valeriano, M.; Steube, N.; Giammarinaro, P. I.; Hochberg, G. K. A.; Glatter, T. et al.; Bange, G.; Diepold, A.; Thanbichler, M.: The virulence regulator VirB from Shigella flexneri uses a CTP-dependent switch mechanism to activate gene expression. Nature Communications 15 (1), 318 (2024)

Carreira, L. A. M.; Szadkowski, D.; Lometto, S.; Hochberg, G. K. A.; Søgaard-Andersen, L.: Molecular basis and design principles of switchable front-rear polarity and directional migration in Myxococcus xanthus. Nature Communications 14 (1), 4056 (2023)

Kremer, K.; Meier, D.; Theis, L.; Miller, S.; Rost-Nasshan, A.; Naing, Y. T.; Zarzycki, J.; Paczia, N.; Serrania, J.; Blumenkamp, P. et al.; Goesmann, A.; Becker, A.; Thanbichler, M.; Hochberg, G. K. A.; Carter, M. S.; Erb, T. J.: Functional degeneracy in Paracoccus denitrificans Pd1222 is coordinated via RamB, which links expression of the Glyoxylate cycle to activity of the Ethylmalonyl-CoA pathway. Applied and Environmental Microbiology 89 (7), e0023823 (2023)

Winiarska, A.; Ramírez-Amador, F.; Hege, D.; Gemmecker, Y.; Prinz, S.; Hochberg, G. K. A.; Heider, J.; Szaleniec, M.; Schuller, J. M.: A bacterial tungsten-containing aldehyde oxidoreductase forms an enzymatic decorated protein nanowire. Science Advances 9 (22), eadg6689 (2023)

Islam, M. I.; Ridone, P.; Lin, A.; Michie, K. A.; Matzke, N. J.; Hochberg, G. K. A.; Baker, M. A. B.: Ancestral reconstruction of the MotA stator subunit reveals that conserved residues far from the pore are required to drive flagellar motility. microLife 4, uqad011 (2023)

Moldenhauer, M.; Tseng, H.-W.; Kraskov, A.; Tavraz, N. N.; Yaroshevich, I. A.; Hildebrandt, P.; Sluchanko, N. N.; Hochberg, G. A.; Essen, L.-O.; Budisa, N. et al.; Korf, L.; Maksimov, E. G.; Friedrich, T.: Parameterization of a single H-bond in orange carotenoid protein by atomic mutation reveals principles of evolutionary design of complex chemical photosystems. Frontiers in Molecular Biosciences 10, 1072606 (2023)

Priyadarshini, N.; Steube, N.; Wiens, D.; Narikawa, R.; Wilde, A.; Hochberg, G. K. A.; Enomoto, G.: Evidence for an early green/red photocycle that precedes the diversification of GAF domain photoreceptor cyanobacteriochromes. Photochemical & Photobiological Sciences 22, pp. 1415 - 1427 (2023)

Steube, N.; Moldenhauer, M.; Weiland, P.; Saman, D.; Kilb, A.; Ramírez Rojas, A. A.; Garg, S.; Schindler, D.; Graumann, P. L.; Benesch, J. L. P. et al.; Bange, G.; Friedrich, T.; Hochberg, G. K. A.: Fortuitously compatible protein surfaces primed allosteric control in cyanobacterial photoprotection. Nature Ecology & Evolution 7, pp. 756 - 767 (2023)

Schulz, L.; Guo, Z.; Zarzycki, J.; Steinchen, W.; Schuller, J. M.; Heimerl, T.; Prinz, S.; Mueller-Cajar, O.; Erb, T. J.; Hochberg, G. K. A.: Evolution of increased complexity and specificity at the dawn of form I Rubiscos. Science 378 (6616), pp. 155 - 160 (2022)

Giammarinaro, P. I.; Young, M. K. M.; Steinchen, W.; Mais, C. N.; Hochberg, G. K. A.; Yang, J.; Stevenson, D. M.; Amador-Noguez, D.; Paulus, A.; Wang, J. D. et al.; Bange, G.: Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. Nature Microbiology 7, 1442–1452 (2022)

Rick, T.; Kreiling, V.; Hoing, A.; Fiedler, S.; Glatter, T.; Steinchen, W.; Hochberg, G. K. A.; Bahre, H.; Seifert, R.; Bange, G. et al.; Knauer, S. K.; Graumann, P. L.; Thormann, K. M.: GGDEF domain as spatial on-switch for a phosphodiesterase by interaction with landmark protein HubP. npj Biofilms and Microbiomes 8, 35 (2022)

Schulz, L.; Sendker, F. L.; Hochberg, G. K. A.: Non-adaptive complexity and biochemical function. Current Opinion in Structural Biology 73, 102339 (2022)

Hernandez-Tamayo, R.; Steube, N.; Heimerl, T.; Hochberg, G. K. A.; Graumann, P. L.: ATPase activity of Bacillus subtilis RecA affects the dynamic formation of RecA filaments at DNA double strand breaks. mSphere 7 (6), e00412-22 (2022)

Lyu, J.; Liu, C.; Zhang, T.; Schrecke, S.; Elam, N. P.; Packianathan, C.; Hochberg, G. K. A.; Russell, D.; Zhao, M.; Laganowsky, A.: Structural basis for lipid and copper regulation of the ABC transporter MsbA. Nature Communications 13, 7291 (2022)

Pillai, A. S.; Hochberg, G. K. A.; Thornton, J. W.: Simple mechanisms for the evolution of protein complexity. Protein Science 31 (11), e4449 (2022)

Feyh, R.; Waeber, N. B.; Prinz, S.; Giammarinaro, P. I.; Bange, G.; Hochberg, G. K. A.; Hartmann, R. K.; Altegoer, F.: Structure and mechanistic features of the prokaryotic minimal RNase P. eLife 10, e70160 (2021)

Hochberg, G. K. A.; Liu, Y.; Marklund, E. G.; Metzger, B. P. H.; Laganowsky, A.; Thornton, J. W.: A hydrophobic ratchet entrenches molecular complexes. Nature 588 (7838), pp. 503 - 508 (2020)