Publications and Outreach

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 Other Publications  •   Outreach

Peer-reviewed Research Articles and Reviews


Journal Article
Schulz, L.; Zarzycki, J.; Steinchen, W.; Hochberg, G. K. A.; Erb, T. J.: Layered entrenchment maintains essentiality in protein-protein interactions. bioRxiv: the preprint server for biology (2024)
Book Chapter
Erb, T. J.: Bringing Photosynthesis 2.0 to Life. In: Curious Future Insight, pp. 49 - 64 (Ed. Betz, U. A.K.). Springer, Cham (2024)
Journal Article
Schmidt, F. V.; Schulz, L.; Zarzycki, J.; Prinz, S.; Oehlmann, N. N.; Erb, T. J.; Rebelein, J. G.: Structural insights into the iron nitrogenase complex. Nature Structural & Molecular Biology 31 (1), pp. 150 - 158 (2024)
Journal Article
Gomez, A.; Erb, T. J.; Grubmüller, H.; Vöhringer-Martinez, E.: Conformational dynamics of the most efficient carboxylase contributes to efficient CO2 fixation. Journal of Chemical Information and Modeling 63 (24), pp. 7807 - 7815 (2023)
Journal Article
Nattermann, M.; Wenk, S.; Pfister, P.; He, H.; Lee, S.H.; Szymanski, W.; Guntermann, N.; Zhu, F.; Nickel, L.; Wallner, C. et al.; Zarzycki, J.; Paczia, N.; Gaißert, N.; Franciò, G.; Leitner, W.; Gonzalez, R.; Erb, T. J.: Engineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo. Nature Communications 14 (1), 2682 (2023)
Journal Article
Marchal, D. G.; Schulz, L.; Schuster, I.; Ivanovska, J.; Paczia, N.; Prinz, S.; Zarzycki, J.; Erb, T. J.: Machine learning-supported enzyme engineering toward improved CO2-fixation of Glycolyl-CoA carboxylase. ACS Synthetic Biology 12 (12), pp. 3521 - 3530 (2023)
Journal Article
Erb, T. J.: Photosynthesis 2.0: Realizing new-to-nature CO2-fixation to overcome the limits of natural metabolism. Cold Spring Harbor Perspectives in Biology, a041669 (2023)
Journal Article
Lee, S. H.; Chou, A.; Nattermann, M.; Zhu, F.; Clomburg, J. M.; Paczia, N.; Erb, T. J.; Gonzalez, R.: Identification of 2-Hydroxyacyl-CoA synthases with high acyloin condensation activity for orthogonal one-carbon bioconversion. ACS Catalysis 13 (18), pp. 12007 - 12020 (2023)
Gomez, A.; Erb, T. J.; Grubmüller, H.; Vöhringer-Martinez, E.: Conformational dynamics of the most efficient carboxylase contributes to efficient CO2 fixation. (2023)
Journal Article
Pfister, P.; Diehl, C.; Hammarlund, E.; Carillo, M.; Erb, T. J.: Enhancing the substrate specificity of Clostridium Succinyl-CoA reductase for synthetic biology and biocatalysis. Biochemistry 61 (11), pp. 1786 - 1793 (2023)
Journal Article
Kremer, K.; Meier, D.; Theis, L.; Miller, S.; Rost-Nasshan, A.; Naing, Y. T.; Zarzycki, J.; Paczia, N.; Serrania, J.; Blumenkamp, P. et al.; Goesmann, A.; Becker, A.; Thanbichler, M.; Hochberg, G. K. A.; Carter, M. S.; Erb, T. J.: Functional degeneracy in Paracoccus denitrificans Pd1222 is coordinated via RamB, which links expression of the Glyoxylate cycle to activity of the Ethylmalonyl-CoA pathway. Applied and Environmental Microbiology 89 (7), e0023823 (2023)
Journal Article
McLean, R.; Schwander, T.; Diehl, C.; Cortina, N. S.; Paczia, N.; Zarzycki, J.; Erb, T. J.: Exploring alternative pathways for the in vitro establishment of the HOPAC cycle for synthetic CO2 fixation. Science Advances 9 (24), eadh4299 (2023)
Journal Article
Recabarren, R.; Tinzl, M.; Saez, D. A.; Gomez, A.; Erb, T. J.; Vöhringer-Martinez, E.: Covalent adduct formation as a strategy for efficient CO2 fixation in Crotonyl-CoA carboxylases/reductases. ACS Catalysis 13 (9), pp. 6230 - 6241 (2023)
Journal Article
Schada v. Borzyskowsi, L.; Schulz-Mirbach, H.; Troncoso Castellanos, M.; Severi, F.; Gomez Coronado, P. A.; Paczia, N.; Glatter, T.; Bar-Even, A.; Lindner, S. N.; Erb, T. J.: Implementation of the β-hydroxyaspartate cycle increases growth performance of Pseudomonas putida on the PET monomer ethylene glycol. Metabolic Engineering 76, pp. 97 - 109 (2023)
Journal Article
Diehl, C.; Gerlinger, P.; Paczia, N.; Erb, T. J.: Synthetic anaplerotic modules for the direct synthesis of complex molecules from CO2. Nature Chemical Biology 19 (2), pp. 168 - 175 (2023)
Journal Article
Pfister, P.; Zarzycki, J.; Erb, T. J.: Structural basis for a cork-up mechanism of the intra-molecular Mesaconyl-CoA transferase. Biochemistry 62 (1), pp. 75 - 84 (2023)
Journal Article
Bierbaumer, S.; Nattermann, M.; Schulz, L.; Zschoche, R.; Erb, T. J.; Winkler, C. K.; Tinzl, M.; Glueck, S. M.: Enzymatic conversion of CO2: From natural to artificial utilization. Chemical Reviews 123 (9), pp. 5702 - 5754 (2023)
Giaveri, S.; Bohra, N.; Diehl, C.; Ballinger, M.; Paczia, N.; Glatter, T.; Erb, T. J.: An interdependent metabolic and genetic network shows emergent properties in vitro. (2023)
Journal Article
Luo, S.; Adam, D.; Giaveri, S.; Barthel, S.; Cestellos-Blanco, S.; Hege, D.; Paczia, N.; Castañeda-Losada, L.; Klose, M.; Arndt, F. et al.; Heider, J.; Erb, T. J.: ATP production from electricity with a new-to-nature electrobiological module. Joule 7 (8), pp. 1745 - 1758 (2023)
Journal Article
Luo, S.; Diehl, C.; He, H.; Bae, Y.; Klose, M.; Claus, P.; Cortina, N. S.; Fernandez, C. A.; Schulz-Mirbach, H. A. M.; McLean, R. et al.; Ramírez Rojas, A. A.; Schindler, D.; Paczia, N.; Erb, T. J.: Construction and modular implementation of the THETA cycle for synthetic CO2 fixation. Nature Catalysis 6 (12), pp. 1228 - 1240 (2023)
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Outreach (Press Releases, Interviews)

Städel Museum, Frankfurt
Gastkommentar, June 2020
[Film 03:41 min.]

nano - "Künstliche Photosynthese: Rohstoff CO2?", June 2020
[Film 05:08 min.]

Regionalmagazin - "Forscher verbessern Fotosynthese", July 2019
[Film 03:39 min.]

"Realizing Synthetic Carbon Dioxide Fixation", September 2017
[Film 29:05 min.]

nano - "Besser als die Natur", September 2017
[Film 05:59 min.]

Designing a More Efficient System for Harnessing Carbon Dioxide, November 2016
[Film 03:59 min.]

Research focus of our group
Global carbon cycling, July 2014
[International Innovation Article]

Enzyme catalysis
An enzyme reaction in slow motion, November 2013
[ETH News feature]

Physiology of GFAJ-1
Extraterrestrial life remain terrestrial, July 2012
[ETH life article]

BBC Science in action, July 2012
[Radio interview]

Swissinfo, July 2012
[Radio interview]

Laborjournal online, July 2012
[Print interview]

Discovery of novel pathways
The salt in the soup of evolution, January 2011
[U of Freiburg Press release]

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