Publications

Werland, L.; Rinn, J.; Malengo, G.; Kholeif, K.; Glatter, T.; Colin, R.; Sourjik, V.; Yuan, J.: Antagonistic small proteins enable magnesium-dependent tuning of two-component signaling. bioRxiv: the preprint server for biology, 2026.05.06.723403 (2026)

Yuan, J.; Koch, H.-G.; Berghoff, B. A.: Functional diversity and molecular interactions of small membrane proteins in bacteria. microLife 6, uqaf035 (2025)

Jordan, B.; Gohil, R.; Prasse, D.; Hellwig, L.; Repnik, U.; Jiang, S.; Yuan, J.; Schmitz, R. A.: Transcription profiling and functional analysis of spRNAs and their corresponding asRNAs in Methanosarcina mazei. bioRxiv: the preprint server for biology, 2025.10.28.685009 (2025)

Remme, D. C. L. E.; Tilg, L.-J.; Pfänder, Y.; Yuan, J.; Narberhaus, F.: Small DUF1127 proteins regulate bacterial phosphate metabolism through protein-protein interactions with the sensor kinase PhoR. microLife 6, uqaf023 (2025)

Jiang, S.; Çelen, G.; Glatter, T.; Niederholtmeyer, H.; Yuan, J.: A cell-free system for functional studies of small membrane proteins. Journal of Biological Chemistry 300 (11), 107850 (2024)

Lazaridi, S.; Yuan, J.; Lemmin, T.: Atomic insights into the signaling landscape of E. coli PhoQ histidine kinase from molecular dynamics simulations. Scientific Reports 14 (1), 17659 (2024)

Jiang, S.; Steup, L. C.; Kippnich, C.; Lazaridi, S.; Malengo, G.; Lemmin, T.; Yuan, J.: The inhibitory mechanism of a small protein reveals its role in antimicrobial peptide sensing. Proceedings of the National Academy of Sciences of the United States of America 120 (41), e2309607120 (2023)

Breuer, R.; Gomes-Filho, J. V.; Yuan, J.; Randau, L.: Transcriptome profiling of Nudix hydrolase gene deletions in the thermoacidophilic archaeon Sulfolobus acidocaldarius. Frontiers in Microbiology 14, 1197877 (2023)

Yadavalli, S. S.; Yuan, J.: Bacterial small membrane proteins: the Swiss army knife of regulators at the lipid bilayer. Journal of Bacteriology 204 (1), e0034421 (2021)

Yadavalli, S. S.; Goh, T.; Carey, J. N.; Malengo, G.; Vellappan, S.; Nickels, B. E.; Sourjik, V.; Goulian, M.; Yuan, J.: Functional Determinants of a Small Protein Controlling a Broadly Conserved Bacterial Sensor Kinase. JOURNAL OF BACTERIOLOGY 202 (16), e00305-20 (2020)

Yuan, J.; Jin, F.; Glatter, T.; Sourjik, V.: Osmosensing by the bacterial PhoQ/PhoP two-component system. Proceedings of the National Academy of Sciences of the United States of America 114 (50), pp. E10792 - E10798 (2017)

Liu, Y.; Dos Santos, P. C.; Zhu, X.; Orlando, R.; Dean, D. R.; Soell, D.; Yuan, J.: Catalytic Mechanism of Sep-tRNA:Cys-tRNA Synthase SULFUR TRANSFER IS MEDIATED BY DISULFIDE AND PERSULFIDE. JOURNAL OF BIOLOGICAL CHEMISTRY 287 (8), pp. 5426 - 5433 (2012)

Hohn, M. J.; Palioura, S.; Su, D.; Yuan, J.; Soell, D.: Genetic analysis of selenocysteine biosynthesis in the archaeon Methanococcus maripaludis. MOLECULAR MICROBIOLOGY 81 (1), pp. 249 - 258 (2011)

Yuan, J.; Gogakos, T.; Babina, A. M.; Soell, D.; Randau, L.: Change of tRNA identity leads to a divergent orthogonal histidyl-tRNA synthetase/tRNA(His) pair. NUCLEIC ACIDS RESEARCH 39 (6), pp. 2286 - 2293 (2011)

Yuan, J.; Hohn, M. J.; Sherrer, R. L.; Palioura, S.; Su, D.; Soell, D.: A tRNA-dependent cysteine biosynthesis enzyme recognizes the selenocysteine-specific tRNA in Escherichia coli. FEBS LETTERS 584 (13), pp. 2857 - 2861 (2010)

Yuan, J.; O'Donoghue, P.; Ambrogelly, A.; Gundllapalli, S.; Sherrer, R. L.; Palioura, S.; Simonovic, M.; Soell, D.: Distinct genetic code expansion strategies for selenocysteine and pyrrolysine are reflected in different aminoacyl-tRNA formation systems. FEBS LETTERS 584 (2), pp. 342 - 349 (2010)

Su, D.; Hohn, M. J.; Palioura, S.; Sherrer, R. L.; Yuan, J.; Soell, D.; O'Donoghue, P.: How an Obscure Archaeal Gene Inspired the Discovery of Selenocysteine Biosynthesis in Humans. IUBMB LIFE 61 (1), pp. 35 - 39 (2009)

Araiso, Y.; Palioura, S.; Ishitani, R.; Sherrer, R. L.; O'Donoghue, P.; Yuan, J.; Oshikane, H.; Domae, N.; DeFranco, J.; Soell, D. et al.; Nureki, O.: Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation. NUCLEIC ACIDS RESEARCH 36 (4), pp. 1187 - 1199 (2008)

Palioura, S.; Yuan, J.; Su, D.; Salazar, J. C.; Araiso, Y.; Nureki, O.; Whitman, W. B.; Soll, D.: RNA-dependent formation of selenocysteine. FEBS JOURNAL 275, p. 156 - 156 (2008)

Sheppard, K.; Yuan, J.; Hohn, M. J.; Jester, B.; Devine, K. M.; Soll, D.: From one amino acid to another: tRNA-dependent amino acid biosynthesis. NUCLEIC ACIDS RESEARCH 36 (6), pp. 1813 - 1825 (2008)

Yuan, J.; Sheppard, K.; Soll, D.: Amino acid modifications on tRNA. ACTA BIOCHIMICA ET BIOPHYSICA SINICA 40 (7), pp. 539 - 553 (2008)

Polycarpo, C.; Sheppard, K.; Randau, L.; Ambrogelly, A.; Cardoso, A. M.; Fukai, S.; Herring, S.; Hohn, M.; Nakamura, Y.; Oshikane, H. et al.; Palioura, S.; Salazar, J. C.; Yuan, J.; Nureki, O.; Soell, D.: Features of Aminoacyl-tRNA Synthesis Unique to Archaea. In: ARCHAEA: MOLECULAR AND CELLULAR BIOLOGY, pp. 198 - + (2007)

Yuan, J.; Sauerwald, A.; Zhu, W.; Major, T.; Roy, H.; Palioura, S.; Jahn, D.; Whitman, W.; Yates III, J.; Ibba, M. et al.; Söll, D.: RNA-Dependent Cysteine Biosynthesis in Archaea. The FASEB Journal 20 (4), pp. A503 - A504 (2006)

Yuan, J.; Palioura, S.; Salazar, J. C.; Su, D.; O'Donoghue, P.; Hohn, M. J.; Cardoso, A. M.; Whitman, W. B.; Soll, D.: RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 103 (50), pp. 18923 - 18927 (2006)

Feng, L.; Yuan, J.; Toogood, H.; Tumbula-Hansen, D.; Soll, D.: Aspartyl-tRNA synthetase requires a conserved proline in the anticodon-binding loop for tRNA(Asn) recognition in vivo. JOURNAL OF BIOLOGICAL CHEMISTRY 280 (21), pp. 20638 - 20641 (2005)

Randau, L.; Calvin, K.; Hall, M.; Yuan, J.; Podar, M.; Li, H.; Soll, D.: The heteromeric Nanoarchaeum equitans splicing endonuclease cleaves noncanonical bulge-helix-bulge motifs of joined tRNA halves. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102 (50), pp. 17934 - 17939 (2005)