Prof. Dr. Lotte Søgaard-Andersen

Bacterial development & differentiation

Curriculum Vitae

Lotte Søgaard-Andersen (born 1959)
M. Sc. thesis (Molecular biology), University of Odense, 1984
Medical Doctor, University of Odense, 1988
Visiting scientist, Institut Pasteur, Paris, 1990
PhD (Molecular biology), University of Odense, 1991
Post-doc, University of Odense, 1991
Assistant professor, University of Odense, 1992
Visiting scientist, Stanford University, 1994
Associate professor, University of Southern Denmark, 1996
Professor, University of Southern Denmark, 2002
Director and Head of the Department of Ecophysiology at the MPI in Marburg, since 2004
Professor for Microbiology at the Philipps-Universität Marburg, since 2008

Group leader at the department

Dr. Simon Ringgaard and Dr. Andreas Diepold

Research area: Bacterial adaptation and differentiation

The overall goal of our research is to unravel the mechanisms that allow bacteria to adapt and differentiate in response to changes in the environment. Bacteria have evolved at least three strategies that allow them to cope with such changes. One strategy centers on changes in gene expression ranging from changes in the expression of relatively few genes to changes in the expression of large numbers of genes culminating in cell differentiation. A second strategy centers on changes in the motility behavior of cells. Finally, a third strategy centers on changes to the cell cycle. To implement these strategies bacterial cells have to process vast amounts of information and then generate the appropriate output response. Information processing is carried out by complex networks of signal transduction proteins. A challenging problem in bacterial adaptation and differentiation is to understand how these protein networks are organized in space and time to allow the ordered execution of various tasks.

 

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