Publications of Helge B. Bode

Journal Article (25)

2024
Journal Article
Bozhüyük, K. A. J.; Präve, L.; Kegler, C.; Schenk, L.; Kaiser, S.; Schelhas, C. S.; Shi, Y.-N.; Kuttenlochner, W.; Schreiber, M.; Kandler, J. et al.; Alanjary, M.; Mohiuddin, T. M.; Groll, M.; Hochberg, G. K. A.; Bode, H. B.: Evolution-inspired engineering of nonribosomal peptide synthetases. Science 383 (6689), eadg4320 (2024)
Journal Article
Touray, M.; Cimen, H.; Bode, E.; Bode, H. B.; Hazir, S.: Effects of Xenorhabdus and Photorhabdus bacterial metabolites on the ovipositional activity of Aedes albopictus. Journal of Pest Science 97 (4), pp. 2203 - 2215 (2024)
Journal Article
Su, L.; Huber, E. M.; Westphalen, M.; Gellner, J.; Bode, E.; Köbel, T.; Grün, P.; Alanjary, M. M.; Glatter, T.; Cirnski, K. et al.; Müller, R.; Schindler, D.; Groll, M.; Bode, H. B.: Isofunctional but structurally different methyltransferases for dithiolopyrrolone diversification. Angewandte Chemie International Edition, e202410799 (2024)
Journal Article
Präve, L.; Kuttenlochner, W.; Tabak, W. W.A.; Langer, C.; Kaiser, M.; Groll, M.; Bode, H. B.: Bioengineering of syrbactin megasynthetases for immunoproteasome inhibitor production. Chem (2024)
Journal Article
Präve, L.; Seyfert, C. E.; Bozhüyük, K. A. J.; Racine, E.; Müller, R.; Bode, H. B.: Investigation of the Odilorhabdin biosynthetic gene cluster using NRPS engineering. Angewandte Chemie International Edition 63 (33), e202406389 (2024)
Journal Article
Touray, M.; Ulug, D.; Gulsen, S. H.; Cimen, H.; Hazir, C.; Bode, H. B.; Hazir, S.: Natural products from Xenorhabdus and Photorhabdus show promise as biolarvicides against Aedes albopictus. Pest Management Science 80 (9), pp. 4231 - 4242 (2024)
Journal Article
Rill, A.; Zhao, L.; Bode, H. B.: Genetic toolbox for Photorhabdus and Xenorhabdus: pSEVA based heterologous expression systems and CRISPR/Cpf1 based genome editing for rapid natural product profiling. Microbial Cell Factories 23, 98 (2024)
2023
Journal Article
Abbood, N.; Effert, J.; Bozhüyük, K. A. J.; Bode, H. B.: Guidelines for optimizing type S nonribosomal peptide synthetases. ACS Synthetic Biology 12 (8), pp. 2432 - 2443 (2023)
Journal Article
Huber, E. M.; Kreling, L.; Heinrich, A. K.; Dunnebacke, M.; Pothig, A.; Bode, H. B.; Groll, M.: A set of closely related methyltransferases for site-specific tailoring of anthraquinone pigments. Structure 31 (5), 573-583.e5. (2023)
Journal Article
Bode, E.; Assmann, D.; Happel, P.; Meyer, E.; Münch, K.; Roessel, N.; Bode, H. B.: easyPACId, a simple method for induced production, isolation, identification, and testing of natural products from Proteobacteria. Bio-protocol 13 (13), e4709 (2023)
Journal Article
Cai, X.; Zhao, L.; Bode, H. B.: Engineering of specific single-module nonribosomal peptide synthetases of the RXP type for the production of defined peptides. ACS Synthetic Biology 12 (1), pp. 203 - 212 (2023)
2022
Journal Article
Kavakli, S.; Grammbitter, G. L. C.; Bode, H. B.: Biosynthesis of the multifunctional isopropylstilbene in Photorhabdus laumondii involves cross-talk between specialized and primary metabolism. Tetrahedron 128, 133116 (2022)
Journal Article
Shi, Y.-M.; Crames, J. J.; Czech, L.; Bozhüyük, K. A. J.; Shi, Y.-N.; Hirschmann, M.; Lamberth, S.; Claus, P.; Paczia, N.; Ruckert, C. et al.; Kalinowski, J.; Bange, G.; Bode, H. B.: Genome mining enabled by biosynthetic characterization uncovers a class of benzoxazolinate-containing natural products in diverse bacteria. Angewandte Chemie, International Edition in English 61 (51), e202206106 (2022)
Journal Article
Shi, Y.-M.; Hirschmann, M.; Shi, Y.-N.; Bode, H. B.: Cleavage off-loading and post-assembly-line conversions yield products with unusual termini during biosynthesis. ACS Chemical Biology 17 (8), pp. 2221 - 2228 (2022)
Journal Article
Abbood, N.; Vo, T. D.; Watzel, J.; Bozhueyuek, K. A. J.; Bode, H. B.: Type S non-ribosomal peptide synthetases for the rapid generation of tailormade peptide libraries. Chemistry – A European Journal 28 (26), e202103963 (2022)
Journal Article
Shi, Y.-M.; Hirschmann, M.; Shi, Y.-N.; Ahmed, S.; Abebew, D.; Tobias, N. J.; Grun, P.; Crames, J. J.; Pöschel, L.; Kuttenlochner, W. et al.; Richter, C.; Herrmann, J.; Muller, R.; Thanwisai, A.; Pidot, S. J.; Stinear, T. P.; Groll, M.; Kim, Y.; Bode, H. B.: Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria. Nature Chemistry 14, pp. 701 - 712 (2022)
2021
Journal Article
Behsaz, B.; Bode, E.; Gurevich, A.; Shi, Y.-N.; Grundmann, F.; Acharya, D.; Caraballo-Rodriguez, A. M.; Bouslimani, A.; Panitchpakdi, M.; Linck, A. et al.; Guan, C.; Oh, J.; Dorrestein, P. C.; Bode, H. B.; Pevzner, P. A.; Mohimani, H.: Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery. Nature Communications 12 (1), 3225 (2021)
Journal Article
Bozhüyük, K. A. J.; Watzel, J.; Abbood, N.; Bode, H. B.: Synthetic zippers as an enabling tool for engineering of non-ribosomal peptide synthetases**. Angewandte Chemie International Edition 60 (32), pp. 17531 - 17538 (2021)
Journal Article
Zhao, L.; Le Chapelain, C.; Brachmann, A. O.; Kaiser, M.; Groll, M.; Bode, H. B.: Activation, structure, biosynthesis and bioactivity of glidobactin-like proteasome inhibitors from Photorhabdus laumondii. ChemBioChem 22 (9), pp. 1582 - 1588 (2021)
Journal Article
Watzel, J.; Duchardt-Ferner, E.; Sarawi, S.; Bode, H. B.; Wohnert, J.: Cooperation between a T domain and a minimal C-terminal docking domain to enable specific assembly in a multiprotein NRPS. Angewandte Chemie International Edition 60 (25), pp. 13685 - 14194 (2021)
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