Publications of H. Link

Journal Article (29)

2022
Journal Article
Stecker, D.; Hoffmann, T.; Link, H.; Commichau, F. M.; Bremer, E.: L-Proline synthesis mutants of Bacillus subtilis overcome osmotic sensitivity by genetically adapting L-Arginine metabolism. Frontiers in Microbiology 13, 908304 (2022)
2021
Journal Article
Gauttam, R.; Desiderato, C. K.; Radoš, D.; Link, H.; Seibold, G. M.; Eikmanns, B. J.: Metabolic Engineering of Corynebacterium glutamicum for Production of UDP-N-Acetylglucosamine. Front Bioeng Biotechnol 9, p. 748510 (2021)
Journal Article
Wang, C.-Y.; Lempp, M.; Farke, N.; Donati, S.; Glatter, T.; Link, H.: Metabolome and proteome analyses reveal transcriptional misregulation in glycolysis of engineered E. coli. Nature Communications 12 (1), 4929 (2021)
Journal Article
Alseekh, S.; Aharoni, A.; Brotman, Y.; Contrepois, K.; D'Auria, J.; Ewald, J.; J, C. E.; Fraser, P. D.; Giavalisco, P.; Hall, R. D. et al.; Heinemann, M.; Link, H.; Luo, J.; Neumann, S.; Nielsen, J.; Perez de Souza, L.; Saito, K.; Sauer, U.; Schroeder, F. C.; Schuster, S.; Siuzdak, G.; Skirycz, A.; Sumner, L. W.; Snyder, M. P.; Tang, H.; Tohge, T.; Wang, Y.; Wen, W.; Wu, S.; Xu, G.; Zamboni, N.; Fernie, A. R.: Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices. Nature Methods 18 (7), pp. 747 - 756 (2021)
Journal Article
Schubert, C.; Winter, M.; Ebert-Jung, A.; Kierszniowska, S.; Nagel-Wolfrum, K.; Schramm, T.; Link, H.; Winter, S.; Unden, G.: C4-dicarboxylates and l-aspartate utilization by Escherichia coli K-12 in the mouse intestine: l-aspartate as a major substrate for fumarate respiration and as a nitrogen source. Environmental Microbiology 23 (5), pp. 2564 - 2577 (2021)
Journal Article
Donati, S.; Kuntz, M.; Pahl, V.; Farke, N.; Beuter, D.; Glatter, T.; Gomes-Filho, J. V.; Randau, L.; Wang, C.-Y.; Link, H.: Multi-omics analysis of CRISPRi-knockdowns identifies mechanisms that buffer decreases of enzymes in E. coli metabolism. Cell Systems 12 (1), pp. 56 - 67.E6 (2021)
Journal Article
Kochanowski, K.; Sander, T.; Link, H.; Chang, J.; Altschuler, S. J.; Wu, L. F.: Systematic alteration of in vitro metabolic environments reveals empirical growth relationships in cancer cell phenotypes. CELL REPORTS 34 (3), 108647 (2021)
Journal Article
Diaz-Pascual, F.; Lempp, M.; Nosho, K.; Jeckel, H.; Jo, J. K.; Neuhaus, K.; Hartmann, R.; Jelli, E.; Hansen, M. F.; Price-Whelan, A. et al.; Dietrich, L. E.; Link, H.; Drescher, K.: Spatial alanine metabolism determines local growth dynamics of Escherichia coli colonies. eLife, 10:e70794 (2021)
2020
Journal Article
Lempp, M.; Lubrano, P.; Bange, G.; Link, H.: Metabolism of non-growing bacteria. BIOLOGICAL CHEMISTRY 401 (12), pp. 1479 - 1485 (2020)
Journal Article
Schramm, T.; Lempp, M.; Beuter, D.; Sierra González, S.; Glatter, T.; Link, H.: High-throughput enrichment of temperature-sensitive argininosuccinate synthetase for two-stage citrulline production in E. coli. METABOLIC ENGINEERING 60, pp. 14 - 24 (2020)
Journal Article
Ni, B.; Colin, R.; Link, H.; Endres, R. G.; Sourjik, V.: Growth-rate dependent resource investment in bacterial motile behavior quantitatively follows potential benefit of chemotaxis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (1), pp. 595 - 601 (2020)
2019
Journal Article
Diaz-Pascual, F.; Hartmann, R.; Lempp, M.; Vidakovic, L.; Song, B.; Jeckel, H.; Thormann, K. M.; Yildiz, F. H.; Dunkel, J.; Link, H. et al.; Nadell, C. D.; Drescher, K.: Breakdown of Vibrio cholerae biofilm architecture induced by antibiotics disrupts community barrier function. NATURE MICROBIOLOGY 4 (12), pp. 2136 - + (2019)
Journal Article
Lempp, M.; Farke, N.; Kuntz, M.; Freibert, S. A.; Lill, R.; Link, H.: Systematic identification of metabolites controlling gene expression in E. coli. NATURE COMMUNICATIONS 10, 4463 (2019)
Journal Article
Boecker, S.; Zahoor, A.; Schramm, T.; Link, H.; Klamt, S.: Broadening the Scope of Enforced ATP Wasting as a Tool for Metabolic Engineering in Escherichia coli. SI 14 (9), 1800438 (2019)
Journal Article
Sander, T.; Wang, C.-Y.; Glatter, T.; Link, H.: CRISPRi-Based Downregulation of Transcriptional Feedback Improves Growth and Metabolism of Arginine Overproducing E. coli. ACS SYNTHETIC BIOLOGY 8 (9), pp. 1983 - 1990 (2019)
Journal Article
Laganenka, L.; Sander, T.; Lagonenko, A.; Chen, Y.; Link, H.; Sourjik, V.: Quorum Sensing and Metabolic State of the Host Control Lysogeny-Lysis Switch of Bacteriophage T1. MBIO 10 (5), e01884-19 (2019)
Journal Article
Sander, T.; Farke, N.; Diehl, C.; Kuntz, M.; Glatter, T.; Link, H.: Allosteric Feedback Inhibition Enables Robust Amino Acid Biosynthesis in E-coli by Enforcing Enzyme Overabundance. CELL SYSTEMS 8 (1), pp. 66 - + (2019)
2018
Journal Article
Beuter, D.; Gomes, J.; Randau, L.; Diaz-Pascual, F.; Drescher, K.; Link, H.: Selective Enrichment of Slow-Growing Bacteria in a Metabolism-Wide CRISPRi Library with a TIMER Protein. ACS SYNTHETIC BIOLOGY 7 (12), pp. 2775 - 2782 (2018)
Journal Article
Buffing, M.; Link, H.; Christodoulou, D.; Sauer, U.: Capacity for instantaneous catabolism of preferred and non-preferred carbon sources in Escherichia coli and Bacillus subtilis. SCIENTIFIC REPORTS 8, 11760 (2018)
Journal Article
Christodoulou, D.; Link, H.; Fuhrer, T.; Kochanowski, K.; Gerosa, L.; Sauer, U.: Reserve Flux Capacity in the Pentose Phosphate Pathway Enables Escherichia coli's Rapid Response to Oxidative Stress. CELL SYSTEMS 6 (5), p. 569 (2018)
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