Publications of G. K. A. Hochberg

Park, Y., Patton, J. E. J., Hochberg, G. K. A. and Thornton, J. W.: (2020) Comment on "Ancient origins of allosteric activation in a Ser-Thr kinase", Science, 370 (6519).

Pillai, A. S., Chandler, S. A., Liu, Y., Signore, A. V., Cortez-Romero, C. R., Benesch, J. L. P., Laganowsky, A., Storz, J. F., Hochberg, G. K. A. and Thornton, J. W.: (2020) Origin of complexity in haemoglobin evolution, Nature, 581 (7809), pp. 480–485.

Malay, A. D., Miyazaki, N., Biela, A., Chakraborti, S., Majsterkiewicz, K., Stupka, I., Kaplan, C. S., Kowalczyk, A., Piette, Bmag, Hochberg, G. K. A., Wu, D., Wrobel, T. P., Fineberg, A., Kushwah, M. S., Kelemen, M., Vavpetic, P., Pelicon, P., Kukura, P., Benesch, J. L. P., Iwasaki, K. and Heddle, J. G.: (2019) An ultra-stable gold-coordinated protein cage displaying reversible assembly, Nature, 569 (7756), pp. 438–442.

Santhanagopalan, I., Degiacomi, M. T., Shepherd, D. A., Hochberg, G. K. A., Benesch, J. L. P. and Vierling, E.: (2018) It takes a dimer to tango: Oligomeric small heat shock proteins dissociate to capture substrate, J Biol Chem, 293 (51), pp. 19511–19521.

Hochberg, G. K. A., Shepherd, D. A., Marklund, E. G., Santhanagoplan, I., Degiacomi, M. T., Laganowsky, A., Allison, T. M., Basha, E., Marty, M. T., Galpin, M. R., Struwe, W. B., Baldwin, A. J., Vierling, E. and Benesch, J. L. P.: (2018) Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions, Science, 359 (6378), pp. 930–935.

Siddiq, M. A., Hochberg, G. K. A. and Thornton, J. W.: (2017) Evolution of protein specificity: insights from ancestral protein reconstruction, Curr Opin Struct Biol, 47, August, pp. 113–122.

Hochberg, G. K. A. and Thornton, J. W.: (2017) Reconstructing Ancient Proteins to Understand the Causes of Structure and Function, Annu Rev Biophys, 46, March, pp. 247–269.

Marty, M. T., Baldwin, A. J., Marklund, E. G., Hochberg, G. K. A., Benesch, J. L. and Robinson, C. V.: (2015) Bayesian deconvolution of mass and ion mobility spectra: from binary interactions to polydisperse ensembles, Anal Chem, 87 (8), pp. 4370–6.

Hochberg, G. K. A., Ecroyd, H., Liu, C., Cox, D., Cascio, D., Sawaya, M. R., Collier, M. P., Stroud, J., Carver, J. A., Baldwin, A. J., Robinson, C. V., Eisenberg, D. S., Benesch, J. L. and Laganowsky, A.: (2014) The structured core domain of alphaB-crystallin can prevent amyloid fibrillation and associated toxicity, Proc Natl Acad Sci U S A, 111 (16), pp. E1562–70.

Hochberg, G. K. A. and Benesch, J. L.: (2014) Dynamical structure of alphaB-crystallin, Prog Biophys Mol Biol, 115 (1), pp. 11–20.

Hilton, G. R., Hochberg, G. K. A., Laganowsky, A., McGinnigle, S. I., Baldwin, A. J. and Benesch, J. L.: (2013) C-terminal interactions mediate the quaternary dynamics of alphaB-crystallin, Philos Trans R Soc Lond B Biol Sci, 368 (1617), p. 20110405.

Herdering, Eva, Reif-Trauttmansdorff, Tristan, Kumar, Anuj, Habenicht, Tim, Hochberg, Georg K. A., Bohn, Stefan, Schuller, Jan and Schmitz, Ruth Anne: (2024) 2-oxoglutarate triggers assembly of active dodecameric Methanosarcina mazei glutamine synthetase, bioRxiv: the preprint server for biology.

Schulz, Luca, Zarzycki, Jan, Steinchen, Wieland, Hochberg, Georg K. A. and Erb, Tobias J.: (2024) Layered entrenchment maintains essentiality in protein-protein interactions., bioRxiv: the preprint server for biology.

Wang, Zihao, Cao, Guodong, Collier, Miranda P., Qiu, Xingyu, Broadway-Stringer, Sophie, Šaman, Dominik, Ng, Jediael Z. Y., Sen, Navoneel, Azad, Amar J., Hooper, Charlotte, Zimmermann, Johannes, McDonough, Michael, Brem, Jürgen, Rabe, Patrick, Song, Haigang, Alderson, T. Reid, Schofield, Christopher J., Bolla, Jani R., Djinovic-Carugo, Kristina, Fürst, Dieter O., Warscheid, Bettina, Degiacomi, Matteo T., Allison, Timothy M., Hochberg, Georg K. A., Robinson, Carol V., Gehmlich, Katja and Benesch, Justin L.P.: (2024) Cardiac stress leads to regulation of Filamin C dimerisation via an ancient phosphorylation-modulated interaction with HSPB7, bioRxiv: the preprint server for biology.

Addison, Holly Gabriela, Glatter, Timo, Hochberg, Georg K. A. and Rebelein, Johannes G.: (2023) Two distinct ferredoxins are essential for nitrogen fixation by the iron nitrogenase in Rhodobacter capsulatus, bioRxiv: the preprint server for biology.

Drobnič, Tina, Cohen, Eli J., Alzheimer, Mona, Froschauer, Kathrin, Svensson, Sarah, Singh, Nanki, Garg, Sriram, Henderson, Louie, Umrekar, Trishant, Nans, Andrea, Ribardo, Deborah, Hochberg, Georg K. A., Hendrixson, David R., Sharma, Cynthia M., Rosenthal, Peter and Beeby, Morgan: (2023) Molecular model of a bacterial flagellar motor in situ reveals a “parts-list” of protein adaptations to increase torque, bioRxiv: the preprint server for biology.

Peña-Diaz, Priscila, Braymer, Joseph J., Vacek, Vojtěch, Zelená, Marie, Lometto, Stefano, Hrdý, Ivan, Treitli, Sebastian C., Hochberg, Georg K. A., Py, Béatrice, Lill, Roland and Hampl, Vladimír: (2023) Characterisation of the SUF FeS cluster machinery in the amitochondriate eukaryote Monocercomonoides exilis, bioRxiv: the preprint server for biology.

Islam, Md Imtiazul, Ridone, Pietro, Lin, Angela, Michie, Katharine A, Matzke, Nicholas J, Hochberg, Georg K. A. and Baker, Matthew AB: (2023) Ancestral reconstruction of the MotA stator subunit reveals that conserved residues far from the pore are required to drive flagellar motility, bioRxiv: the preprint server for biology.

Carreira, Luis Antonio Menezes, Szadkowski, Dobromir, Lometto, Stefano, Hochberg, Georg K. A. and Søgaard-Andersen, Lotte: (2022) Molecular basis and design principles of a system for switchable front-rear polarity and directional migration, bioRxiv: the preprint server for biology.

Bozhüyük, Kenan A. J., Präve, Leonard, Kegler, Carsten, Kaiser, Sebastian, Shi, Yan-Ni, Kuttenlochner, Wolfgang, Schenk, Leonie, Mohiuddin, T. M., Groll, Michael, Hochberg, Georg K. A. and Bode, Helge B.: (2022) Evolution inspired engineering of megasynthetases, bioRxiv: the preprint server for biology.