Non-canonical molecular biology of bacteriophages

Microbiology Seminar Series

  • Date: Jun 5, 2023
  • Time: 01:15 PM (Local Time Germany)
  • Speaker: Dr. Maria Sokolova
  • Max Planck Institute for Multidisciplinary Sciences, Department of Molecular Biology, Göttingen
  • Location: MPI for Terrestrial Microbiology
  • Room: Lecture Hall / Hybrid
  • Host: Prof. Dr. Tobias Erb
  • Contact: toerb@mpi-marburg.mpg.de

Bacteriophages have a high speed of evolution that allows them to develop different strategies to overcome bacterial defence mechanisms and use the host resources to produce new phage particles efficiently. The main topic of the seminar will be the non-canonical transcription enzymes evolved in bacteriophages, such as 1) RNA polymerase recognising deoxyuridine in phage genomic DNA, 2) bacteriophage RNA polymerase evolutionarily related to eukaryotic RNA-dependent RNA polymerases, and 3) RNA polymerase, which is a part of an extraordinarily long tail of a thermophilic bacteriophage.

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