Synthetic bacterial communities to probe microbial community functions

Microbiology Seminar Series

  • Date: Nov 30, 2020
  • Time: 16:00
  • Speaker: Prof. Dr. Bärbel Stecher
  • Max-von-Pettenkofer Institut, München
  • Location: Zoom, Webinar
  • Host: Prof. Dr. Knut Drescher
  • Contact: k.drescher@mpi-marburg.mpg.de

The gastrointestinal tract is a highly dynamic microbial ecosystem that controls human health through its collective behavior. Microbial communities harbor hundreds of bacteria that form complex metabolic networks. Efficient metabolic interactions are essential for dietary breakdown, production of bioactive metabolites and pathogen exclusion. The lack of suitable model systems has limited our current understanding of the role of individual community members in host-microbiota interactions and resistance to infections. In my lab, we use synthetic bacterial communities that we can study in silico, in vitro and in gnotobiotic mouse models. We aim to understand, how individual strains within a bacterial consortium influence complex disease-relevant functions and provide necessary insight to develop strategies to steer microbial communities towards beneficial interactions promoting human health.

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