Graduate Students Mini Symposium VI 2020
- Datum: 18.05.2020
- Uhrzeit: 16:00
- Ort: MPI for Terrestrial Microbiology
- Raum: Online event
- Gastgeber: IMPRS
- Kontakt: email@example.com
16:00 Hui Qi Loh (AG Brune)
The currency of energy in the hindgut – examples of how acetate produced and consumed in the termite microbiota
Termites are efficient digesters of lignocellulosic biomass. The digestion of lignocellulose is mediated by a diverse assemblage of bacteria and archaea, where the key metabolic processes – fermentation, methanogenesis and acetogenesis happen. Short chain fatty acids (SCFAs), in particular, acetate, has been identified as an important substrate for termites as acetate serves as its carbon and energy source of the termite host. Through phylogenomic analyses of the archaeal phylum Bathyarchaeota and the bacterial phylum Chloroflexi, this talk discusses how two different phlya produce and consume acetate using the same pathway.
16:30 Revathi Pulpetta (AG Thanbichler)
Mapping the interaction interfaces between factors involved in MipZ-dependent division site placement in Caulobacter crescentus
Caulobacter crescentus is a Gram-negative alphaproteobacterium that divides asymmetrically to produce a swarmer cell and a stalked cell. The chromosome is arranged within the cell in a longitudinal manner, with ori tethered to one pole through interaction of the ori-associated protein ParB with the pole-organising protein PopZ. As part of the ParABS DNA partitioning system, ParB also critically contributes to chromosome segregation, which is driven by dynamic interaction of ParB with the nucleoid-associated ATPase ParA. Finally, ParB also interacts with the cell division inhibitor MipZ, a gradient-forming ATPase related to ParA that couples chromosome segregation to the positioning of the cytokinetic machinery at midcell. In this talk, I will present studies that aim to unravel the mode of interaction of ParB with its interaction partners to understand how the different functions of this protein are coordinated at the molecular level.