Publications

Lago-Maciel, A.; Herzog, M.; Rebelein, J. G.: Functional insights into the nitrogenase-like enzyme superfamily. Trends in Biochemical Sciences 51 (2), pp. 187 - 202 (2026)

Lago-Maciel, A.; Soares, J. C.; Zarzycki, J.; Buchanan, C. J.; Reif-Trauttmansdorff, T.; Schmidt, F. V.; Lometto, S.; Paczia, N.; Schuller, J. M.; Hansen, D. F. et al.; Heller, G. T.; Prinz, S.; Hochberg, G. K. A.; Pierik, A. J.; Rebelein, J. G.: Methylthio-alkane reductases use nitrogenase metalloclusters for carbon–sulfur bond cleavage. Nature Catalysis 8 (10), pp. 1089 - 1099 (2025)

Ren, M.; Li, D.; Addison, H.; Noteborn, W. E. M.; Andeweg, E. H.; Glatter, T.; de Winde, J. H.; Rebelein, J. G.; Lamers, M. H.; Schada von Borzyskowski, L.: NAD-dependent dehydrogenases enable efficient growth of Paracoccus denitrificans on the PET monomer ethylene glycol. Nature Communications 16 (1), 5845 (2025)

Addison, H.; Pfister, P.; Lago Maciel, A.; Erb, T. J.; Pierik, A. J.; Rebelein, J. G.: Two key ferredoxins for nitrogen fixation have different specificities and biophysical properties. Chemistry – A European Journal 31 (37), e202500844 (2025)

Ren, M.; Addison, H. G.; Andeweg, E.; Noteborn, W.; Glatter, T.; Rebelein, J. G.; Lamers, M.; Schada von Borzyskowski, L.: FBII-033 - Investigation of ethylene glycol metabolism in Paracoccus denitrificans. New Biotechnology 85, p. 179 (2025)

Oehlmann, N. N.; Rebelein, J. G.: Generating site saturation mutagenesis libraries and transferring them to broad host-range plasmids using Golden Gate cloning. In: Golden Gate Cloning. Methods in Molecular Biology, Vol. 2850, pp. 251 - 264 (Ed. Schindler, D.). Humana, New York, NY (2025)

Oehlmann, N. N.; Schmidt, F. V.; Herzog, M.; Goldman, A. L.; Rebelein, J. G.: The iron nitrogenase reduces carbon dioxide to formate and methane under physiological conditions: A route to feedstock chemicals. Science Advances 10 (33), eado7729 (2024)

Körner, D.; Schäfer, N. M.; Lagares Jr., A.; Birmes, L.; Oehlmann, N. N.; Addison, H. G.; Pöhl, S.; Thanbichler, M.; Rebelein, J. G.; Petersen, J. et al.; Becker, A.: Modular low-copy-number plasmid vectors for Rhodobacterales with extended host range in Alphaproteobacteria. ACS Synthetic Biology 13 (5), pp. 1537 - 1548 (2024)

Addison, H. G.; Glatter, T.; Hochberg, G. K. A.; Rebelein, J. G.: Two distinct ferredoxins are essential for nitrogen fixation by the iron nitrogenase in Rhodobacter capsulatus. mBio 15 (3), e0331423 (2024)

Schmidt, F. V.; Schulz, L.; Zarzycki, J.; Prinz, S.; Oehlmann, N. N.; Erb, T. J.; Rebelein, J. G.: Structural insights into the iron nitrogenase complex. Nature Structural & Molecular Biology 31 (1), pp. 150 - 158 (2024)

Oehlmann, N. N.; Schmidt, F. V.; Herzog, M.; Goldman, A. L.; Rebelein, J. G.: CO₂ reduction by the iron nitrogenase competes with N₂ fixation under physiological conditions. bioRxiv: the preprint server for biology, 2023.11.30.569367 (2023)

Ernst, L.; Barayeu, U.; Hädeler, J.; Dick, T. P.; Klatt, J. M.; Keppler, F.; Rebelein, J. G.: Methane formation driven by light and heat prior to the origin of life and beyond. Nature Communications 14 (1), 4364 (2023)

Ernst, L.; Steinfeld, B. K.; Barayeu, U.; Klintzsch, T.; Kurth, M.; Grimm, D.; Dick, T. P.; Rebelein, J. G.; Bischofs, I. B.; Keppler, F.: Methane formation driven by reactive oxygen species across all living organisms. Nature 603 (7901), pp. 482 - 487 (2022)

Oehlmann, N. N.; Rebelein, J. G.: The conversion of carbon monoxide and carbon dioxide by nitrogenases. Chembiochem 23, e202100453 (2022)

Rupnik, K.; Rettberg, L.; Tanifuji, K.; Rebelein, J. G.; Ribbe, M. W.; Hu, Y.; Hales, B. J.: An EPR and VTVH MCD spectroscopic investigation of the nitrogenase assembly protein NifB. Journal of Biological Inorganic Chemistry 26, pp. 403 - 410 (2021)

Stein, A.; Chen, D.; Igareta, N. V.; Cotelle, Y.; Rebelein, J. G.; Ward, T. R.: A dual anchoring strategy for the directed evolution of improved artificial transfer hydrogenases based on carbonic anhydrase. ACS Central Science 7 (11), pp. 1874 - 1884 (2021)

Serrano-Plana, J.; Rumo, C.; Rebelein, J. G.; Peterson, R. L.; Barnet, M.; Ward, T. R.: Enantioselective Hydroxylation of Benzylic C(sp(3))-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology. J Am Chem Soc 142 (24), pp. 10617 - 10623 (2020)

Rebelein, J. G.; Cotelle, Y.; Garabedian, B.; Ward, T. R.: Chemical Optimization of Whole-Cell Transfer Hydrogenation Using Carbonic Anhydrase as Host Protein. ACS CATALYSIS 9 (5), pp. 4173 - 4178 (2019)

Sabatino, V.; Rebelein, J. G.; Ward, T. R.: "Close-to-Release": Spontaneous Bioorthogonal Uncaging Resulting from Ring-Closing Metathesis. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 141 (43), pp. 17048 - 17052 (2019)

Wu, S.; Zhou, Y.; Rebelein, J. G.; Kuhn, M.; Mallin, H.; Zhao, J.; Igareta, N. V.; Ward, T. R.: Breaking Symmetry: Engineering Single-Chain Dimeric Streptavidin as Host for Artificial Metalloenzymes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 141 (40), pp. 15869 - 15878 (2019)

Rebelein, J. G.; Lee, C. C.; Newcomb, M.; Hu, Y.; Ribbe, M. W.: Characterization of an M-Cluster-Substituted Nitrogenase VFe Protein. MBIO 9 (2), e00310-18 (2018)

Rebelein, J. G.; Ward, T. R.: In vivo catalyzed new-to-nature reactions. CURRENT OPINION IN BIOTECHNOLOGY 53, pp. 106 - 114 (2018)

Zhao, J.; Rebelein, J. G.; Mallin, H.; Trindler, C.; Pellizzoni, M. M.; Ward, T. R.: Genetic Engineering of an Artificial Metalloenzyme for Transfer Hydrogenation of a Self-Immolative Substrate in Escherichia coil's Periplasm. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 140 (41), pp. 13171 - 13175 (2018)

Rebelein, J. G.; Stiebritz, M. T.; Lee, C. C.; Hu, Y.: Activation and reduction of carbon dioxide by nitrogenase iron proteins. NATURE CHEMICAL BIOLOGY 13 (2), pp. 147 - 149 (2017)

Wiig, J. A.; Lee, C. C.; Rebelein, J. G.; Sickerman, N. S.; Tanifuji, K.; Stiebritz, M. T.; Hu, Y.; Ribbe, M. W.: CHAPTER 9 Biosynthesis of the M-Cluster of Mo-Nitrogenase. In: Molybdenum and Tungsten Enzymes: Biochemistry, pp. 297 - 312. The Royal Society of Chemistry (2017)

Fay, A. W.; Blank, M. A.; Rebelein, J. G.; Lee, C. C.; Ribbe, M. W.; Hedman, B.; Hodgson, K. O.; Hu, Y.: Assembly scaffold NifEN: A structural and functional homolog of the nitrogenase catalytic component. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 113 (34), pp. 9504 - 9508 (2016)

Rebelein, J. G.; Lee, C. C.; Hu, Y.; Ribbe, M. W.: The in vivo hydrocarbon formation by vanadium nitrogenase follows a secondary metabolic pathway. NATURE COMMUNICATIONS 7, 13641 (2016)

Rebelein, J. G.; Hu, Y.; Ribbe, M. W.: Widening the Product Profile of Carbon Dioxide Reduction by Vanadium Nitrogenase. CHEMBIOCHEM 16 (14), pp. 1993 - 1996 (2015)

Rebelein, J. G.; Hu, Y.; Ribbe, M. W.: Differential Reduction of CO2 by Molybdenum and Vanadium Nitrogenases. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 53 (43), pp. 11543 - 11546 (2014)

Wiig, J. A.; Rebelein, J. G.; Hu, Y.: Nitrogenase Complex. In: eLS (Ed. John Wiley & Sons, Ltd) (2014)

Moser, J.; Lange, C.; Krausze, J.; Rebelein, J. G.; Schubert, W.-D.; Ribbe, M. W.; Heinz, D. W.; Jahn, D.: Structure of ADP-aluminium fluoride-stabilized protochlorophyllide oxidoreductase complex. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110 (6), pp. 2094 - 2098 (2013)