Publications of G. K. A. Hochberg

Park, Y.; Patton, J. E. J.; Hochberg, G. K. A.; Thornton, J. W.: Comment on "Ancient origins of allosteric activation in a Ser-Thr kinase". Science 370 (6519) (2020)

Pillai, A. S.; Chandler, S. A.; Liu, Y.; Signore, A. V.; Cortez-Romero, C. R.; Benesch, J. L. P.; Laganowsky, A.; Storz, J. F.; Hochberg, G. K. A.; Thornton, J. W.: Origin of complexity in haemoglobin evolution. Nature 581 (7809), pp. 480 - 485 (2020)

Malay, A. D.; Miyazaki, N.; Biela, A.; Chakraborti, S.; Majsterkiewicz, K.; Stupka, I.; Kaplan, C. S.; Kowalczyk, A.; Piette, B.; Hochberg, G. K. A. et al.; Wu, D.; Wrobel, T. P.; Fineberg, A.; Kushwah, M. S.; Kelemen, M.; Vavpetic, P.; Pelicon, P.; Kukura, P.; Benesch, J. L. P.; Iwasaki, K.; Heddle, J. G.: An ultra-stable gold-coordinated protein cage displaying reversible assembly. Nature 569 (7756), pp. 438 - 442 (2019)

Santhanagopalan, I.; Degiacomi, M. T.; Shepherd, D. A.; Hochberg, G. K. A.; Benesch, J. L. P.; Vierling, E.: It takes a dimer to tango: Oligomeric small heat shock proteins dissociate to capture substrate. J Biol Chem 293 (51), pp. 19511 - 19521 (2018)

Hochberg, G. K. A.; Shepherd, D. A.; Marklund, E. G.; Santhanagoplan, I.; Degiacomi, M. T.; Laganowsky, A.; Allison, T. M.; Basha, E.; Marty, M. T.; Galpin, M. R. et al.; Struwe, W. B.; Baldwin, A. J.; Vierling, E.; Benesch, J. L. P.: Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions. Science 359 (6378), pp. 930 - 935 (2018)

Siddiq, M. A.; Hochberg, G. K. A.; Thornton, J. W.: Evolution of protein specificity: insights from ancestral protein reconstruction. Curr Opin Struct Biol 47, pp. 113 - 122 (2017)

Hochberg, G. K. A.; Thornton, J. W.: Reconstructing Ancient Proteins to Understand the Causes of Structure and Function. Annu Rev Biophys 46, pp. 247 - 269 (2017)

Marty, M. T.; Baldwin, A. J.; Marklund, E. G.; Hochberg, G. K. A.; Benesch, J. L.; Robinson, C. V.: Bayesian deconvolution of mass and ion mobility spectra: from binary interactions to polydisperse ensembles. Anal Chem 87 (8), pp. 4370 - 6 (2015)

Hochberg, G. K. A.; Ecroyd, H.; Liu, C.; Cox, D.; Cascio, D.; Sawaya, M. R.; Collier, M. P.; Stroud, J.; Carver, J. A.; Baldwin, A. J. et al.; Robinson, C. V.; Eisenberg, D. S.; Benesch, J. L.; Laganowsky, A.: The structured core domain of alphaB-crystallin can prevent amyloid fibrillation and associated toxicity. Proc Natl Acad Sci U S A 111 (16), pp. E1562 - 70 (2014)

Hochberg, G. K. A.; Benesch, J. L.: Dynamical structure of alphaB-crystallin. Prog Biophys Mol Biol 115 (1), pp. 11 - 20 (2014)

Hilton, G. R.; Hochberg, G. K. A.; Laganowsky, A.; McGinnigle, S. I.; Baldwin, A. J.; Benesch, J. L.: C-terminal interactions mediate the quaternary dynamics of alphaB-crystallin. Philos Trans R Soc Lond B Biol Sci 368 (1617), p. 20110405 (2013)

Herdering, E.; Reif-Trauttmansdorff, T.; Kumar, A.; Habenicht, T.; Hochberg, G. K. A.; Bohn, S.; Schuller, J.; Schmitz, R. A.: 2-oxoglutarate triggers assembly of active dodecameric Methanosarcina mazei glutamine synthetase. (2024)

Schulz, L.; Zarzycki, J.; Steinchen, W.; Hochberg, G. K. A.; Erb, T. J.: Layered entrenchment maintains essentiality in protein-protein interactions. (2024)

Wang, Z.; Cao, G.; Collier, M. P.; Qiu, X.; Broadway-Stringer, S.; Šaman, D.; Ng, J. Z. Y.; Sen, N.; Azad, A. J.; Hooper, C. et al.; Zimmermann, J.; McDonough, M.; Brem, J.; Rabe, P.; Song, H.; Alderson, T. R.; Schofield, C. J.; Bolla, J. R.; Djinovic-Carugo, K.; Fürst, D. O.; Warscheid, B.; Degiacomi, M. T.; Allison, T. M.; Hochberg, G. K. A.; Robinson, C. V.; Gehmlich, K.; Benesch, J. L.P.: Cardiac stress leads to regulation of Filamin C dimerisation via an ancient phosphorylation-modulated interaction with HSPB7. (2024)

Addison, H. G.; Glatter, T.; Hochberg, G. K. A.; Rebelein, J. G.: Two distinct ferredoxins are essential for nitrogen fixation by the iron nitrogenase in Rhodobacter capsulatus. (2023)

Drobnič, T.; Cohen, E. J.; Alzheimer, M.; Froschauer, K.; Svensson, S.; Singh, N.; Garg, S.; Henderson, L.; Umrekar, T.; Nans, A. et al.; Ribardo, D.; Hochberg, G. K. A.; Hendrixson, D. R.; Sharma, C. M.; Rosenthal, P.; Beeby, M.: Molecular model of a bacterial flagellar motor in situ reveals a “parts-list” of protein adaptations to increase torque. (2023)

Islam, M. I.; Ridone, P.; Lin, A.; Michie, K. A.; Matzke, N. J.; Hochberg, G. K. A.; Baker, M. A.: Ancestral reconstruction of the MotA stator subunit reveals that conserved residues far from the pore are required to drive flagellar motility. (2023)

Peña-Diaz, P.; Braymer, J. J.; Vacek, V.; Zelená, M.; Lometto, S.; Hrdý, I.; Treitli, S. C.; Hochberg, G. K. A.; Py, B.; Lill, R. et al.; Hampl, V.: Characterisation of the SUF FeS cluster machinery in the amitochondriate eukaryote Monocercomonoides exilis. (2023)

Carreira, L. A. M.; Szadkowski, D.; Lometto, S.; Hochberg, G. K. A.; Søgaard-Andersen, L.: Molecular basis and design principles of a system for switchable front-rear polarity and directional migration. (2022)

Bozhüyük, K. A. J.; Präve, L.; Kegler, C.; Kaiser, S.; Shi, Y.-N.; Kuttenlochner, W.; Schenk, L.; Mohiuddin, T. M.; Groll, M.; Hochberg, G. K. A. et al.; Bode, H. B.: Evolution inspired engineering of megasynthetases. (2022)