Publications
2023
Journal Article
89 (7), e0023823 (2023)
Functional Degeneracy in Paracoccus denitrificans Pd1222 Is Coordinated via RamB, Which Links Expression of the Glyoxylate Cycle to Activity of the Ethylmalonyl-CoA Pathway. Applied and Environmental Microbiology
Journal Article
9 (22), eadg6689 (2023)
A bacterial tungsten-containing aldehyde oxidoreductase forms an enzymatic decorated protein nanowire. Science Advances
Journal Article
14 (1), 4056 (2023)
Molecular basis and design principles of switchable front-rear polarity and directional migration in Myxococcus xanthus. Nature Communications
Preprint
Molecular model of a bacterial flagellar motor in situ reveals a “parts-list” of protein adaptations to increase torque. (2023)
Preprint
Ancestral reconstruction of the MotA stator subunit reveals that conserved residues far from the pore are required to drive flagellar motility. (2023)
Journal Article
4, uqad011 (2023)
Ancestral reconstruction of the MotA stator subunit reveals that conserved residues far from the pore are required to drive flagellar motility. microLife
Journal Article
10, p. 1072606 - 1072606 (2023)
Parameterization of a single H-bond in Orange Carotenoid Protein by atomic mutation reveals principles of evolutionary design of complex chemical photosystems. Frontiers in molecular biosciences
Preprint
Characterisation of the SUF FeS cluster machinery in the amitochondriate eukaryote Monocercomonoides exilis. (2023)
Journal Article
22, pp. 1415 - 1427 (2023)
Evidence for an early green/red photocycle that precedes the diversification of GAF domain photoreceptor cyanobacteriochromes. Photochemical & photobiological sciences
Journal Article
7, pp. 756 - 767 (2023)
Fortuitously compatible protein surfaces primed allosteric control in cyanobacterial photoprotection. Nature Ecology & Evolution 2022
Journal Article
378 (6616), pp. 155 - 160 (2022)
Evolution of increased complexity and specificity at the dawn of form I Rubiscos. Science
Journal Article
Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. Nat Microbiol (2022)
Journal Article
8 (1), p. 35 (2022)
GGDEF domain as spatial on-switch for a phosphodiesterase by interaction with landmark protein HubP. NPJ Biofilms Microbiomes
Journal Article
73, p. 102339 (2022)
Non-adaptive complexity and biochemical function. Curr Opin Struct Biol
Preprint
Evolution Inspired Engineering of Megasynthetases. (2022)
Preprint
Molecular basis and design principles of a system for switchable front-rear polarity and directional migration. (2022)
Journal Article
ATPase Activity of Bacillus subtilis RecA Affects the Dynamic Formation of RecA Filaments at DNA Double Strand Breaks. mSphere, p. e0041222 - e0041222 (2022)
Preprint
ATPase activity of <em>B. subtilis</em> RecA affects the dynamic formation of RecA filaments at DNA double strand breaks. (2022)
Preprint
Structural basis for lipid and copper regulation of the ABC transporter MsbA. (2022)
Journal Article
13 (1) (2022)
Structural basis for lipid and copper regulation of the ABC transporter MsbA. Nature communications
Journal Article
31 (11), e4449 (2022)
Simple mechanisms for the evolution of protein complexity. PROTEIN SCIENCE 2021
Journal Article
10, e70160 (2021)
Structure and mechanistic features of the prokaryotic minimal RNase P. eLife
Preprint
Construction of multicellular yeast networks using the communication toolkit with variable specificity and attenuation. (2021)
2020
Journal Article
588 (7838), pp. 503 - 508 (2020)
A hydrophobic ratchet entrenches molecular complexes. Nature
Journal Article
370 (6519) (2020)
Comment on "Ancient origins of allosteric activation in a Ser-Thr kinase". Science
Journal Article
581 (7809), pp. 480 - 485 (2020)
Origin of complexity in haemoglobin evolution. Nature 2019
Journal Article
569 (7756), pp. 438 - 442 (2019)
An ultra-stable gold-coordinated protein cage displaying reversible assembly. Nature 2018
Journal Article
293 (51), pp. 19511 - 19521 (2018)
It takes a dimer to tango: Oligomeric small heat shock proteins dissociate to capture substrate. J Biol Chem
Journal Article
359 (6378), pp. 930 - 935 (2018)
Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions. Science 2017
Journal Article
47, pp. 113 - 122 (2017)
Evolution of protein specificity: insights from ancestral protein reconstruction. Curr Opin Struct Biol
Journal Article
46, pp. 247 - 269 (2017)
Reconstructing Ancient Proteins to Understand the Causes of Structure and Function. Annu Rev Biophys 2015
Journal Article
87 (8), pp. 4370 - 6 (2015)
Bayesian deconvolution of mass and ion mobility spectra: from binary interactions to polydisperse ensembles. Anal Chem 2014
Journal Article
111 (16), pp. E1562 - 70 (2014)
The structured core domain of alphaB-crystallin can prevent amyloid fibrillation and associated toxicity. Proc Natl Acad Sci U S A
Journal Article
115 (1), pp. 11 - 20 (2014)
Dynamical structure of alphaB-crystallin. Prog Biophys Mol Biol 2013
Journal Article
368 (1617), p. 20110405 (2013)
C-terminal interactions mediate the quaternary dynamics of alphaB-crystallin. Philos Trans R Soc Lond B Biol Sci