Publications
Members of the Metabolomics Core Facility are only included in the authors list, if they contributed intellectually to a paper. In cases where we provide only standard analytical services, we kindly ask to be mentioned in the acknowledgement.
Journal Article (36)
2022
Journal Article
61 (50), e202213239 (2022)
The Function of Two Radical-SAM Enzymes, HcgA and HcgG, in the Biosynthesis of the [Fe]-Hydrogenase Cofactor. Angew Chem Int Ed Engl
Journal Article
Genome Mining Enabled by Biosynthetic Characterization Uncovers a Class of Benzoxazolinate-Containing Natural Products in Diverse Bacteria. Angew Chem Int Ed Engl (2022)
Journal Article
7 (5), p. e0040322 (2022)
Methylocystis sp. Strain SC2 Acclimatizes to Increasing NH4(+) Levels by a Precise Rebalancing of Enzymes and Osmolyte Composition. mSystems
Journal Article
13 (1), p. 3876 (2022)
A versatile active learning workflow for optimization of genetic and metabolic networks. Nat Commun
Journal Article
61 (22), p. e202200994 (2022)
In Vitro Biosynthesis of the [Fe]-Hydrogenase Cofactor Verifies the Proposed Biosynthetic Precursors. Angew Chem Int Ed Engl 2021
Journal Article
11 (9), pp. 5396 - 5404 (2021)
Engineering a Highly Efficient Carboligase for Synthetic One-Carbon Metabolism. ACS Catal
Journal Article
60 (38), pp. 21056 - 21061 (2021)
Bioelectrocatalytic Cofactor Regeneration Coupled to CO2 Fixation in a Redox-Active Hydrogel for Stereoselective C-C Bond Formation. Angew Chem Int Ed Engl
Journal Article
60 (30), pp. 16420 - 16425 (2021)
A Modular In Vitro Platform for the Production of Terpenes and Polyketides from CO2. Angew Chem Int Ed Engl
Journal Article
118 (21) (2021)
A synthetic C4 shuttle via the beta-hydroxyaspartate cycle in C3 plants. Proceedings of the National Academy of Sciences of the United States of America 2020
Journal Article
61, pp. 181 - 196 (2020)
Hydrogen utilization by Methylocystis sp. strain SC2 expands the known metabolic versatility of type IIa methanotrophs. METABOLIC ENGINEERING
Journal Article
9, e54207 (2020)
Underground isoleucine biosynthesis pathways in E. coli. ELIFE
Journal Article
59 (14), pp. 5526 - 5530 (2020)
Oxalyl-CoA Decarboxylase Enables Nucleophilic One-Carbon Extension of Aldehydes to Chiral α-Hydroxy Acids. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Journal Article
368 (6491), pp. 649 - + (2020)
Light-powered CO2 fixation in a chloroplast mimic with natural and synthetic parts. SI 2019
Journal Article
575 (7783), pp. 500 - + (2019)
Marine Proteobacteria metabolize glycolate via the β-hydroxyaspartate cycle. NATURE
Journal Article
10, 2128 (2019)
Life After Secretion-Yersinia enterocolitica Rapidly Toggles Effector Secretion and Can Resume Cell Division in Response to Changing External Conditions. FRONTIERS IN MICROBIOLOGY
Journal Article
58 (4), pp. 259 - 275 (2019)
3-Phosphoglycerate Transhydrogenation Instead of Dehydrogenation Alleviates the Redox State Dependency of Yeast de Novo L-Serine Synthesis. SI
Journal Article
21 (9), pp. 1426 - 1445 (2019)
Connecting environmental exposure and neurodegeneration using cheminformatics and high resolution mass spectrometry: potential and challenges. ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
Journal Article
142, pp. 50 - 58 (2019)
NAD(P)HX dehydratase (NAXD) deficiency: a novel neurodegenerative disorder exacerbated by febrile illnesses. BRAIN
Journal Article
116 (4), pp. 1241 - 1250 (2019)
Failure to eliminate a phosphorylated glucose analog leads to neutropenia in patients with G6PT and G6PC3 deficiency. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2018
Journal Article
14 (12), p. 1127 (2018)
The multicatalytic compartment of propionyl-CoA synthase sequesters a toxic metabolite. NATURE CHEMICAL BIOLOGY
Journal Article
293 (44), pp. 17200 - 17207 (2018)
InhA, the enoyl-thioester reductase from Mycobacterium tuberculosis forms a covalent adduct during catalysis. JOURNAL OF BIOLOGICAL CHEMISTRY
Journal Article
25 (7), p. 833 (2018)
Combining Promiscuous Acyl-CoA Oxidase and Enoyl-CoA Carboxylase/Reductases for Atypical Polyketide Extender Unit Biosynthesis. CELL CHEMICAL BIOLOGY
Journal Article
285 (18), pp. 3376 - 3401 (2018)
NAD(P)HX repair deficiency causes central metabolic perturbations in yeast and human cells. FEBS JOURNAL
Journal Article
18 (20), pp. 3172 - 3183 (2018)
Millifluidic culture improves human midbrain organoid vitality and differentiation. LAB ON A CHIP
Journal Article
4, 3 (2018)
Natural variation of chronological aging in the Saccharomyces cerevisiae species reveals diet-dependent mechanisms of life span control. NPJ AGING AND MECHANISMS OF DISEASE 2017
Journal Article
13 (4), pp. 363 - 365 (2017)
Engineering fatty acid synthases for directed polyketide production. Nature Chemical Biology
Journal Article
114 (16), pp. E3233 - E3242 (2017)
Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Journal Article
7 (1), p. 42757 (2017)
In Vitro Characterization and Concerted Function of Three Core Enzymes of a Glycyl Radical Enzyme - Associated Bacterial Microcompartment. Scientific Reports 2016
Journal Article
21 (4), 517 (2016)
A Chemo-Enzymatic Road Map to the Synthesis of CoA Esters. Molecules
Journal Article
291 (12), pp. 6036 - 6058 (2016)
Saccharomyces cerevisiae Forms d-2-Hydroxyglutarate and Couples Its Degradation to d-Lactate Formation via a Cytosolic Transhydrogenase. JOURNAL OF BIOLOGICAL CHEMISTRY
Journal Article
354 (6314), pp. 900 - 904 (2016)
A synthetic pathway for the fixation of carbon dioxide in vitro. Science 2014
Journal Article
111 (2), pp. 359 - 371 (2014)
Beyond Growth Rate 0.6: What Drives Corynebacterium glutamicum to Higher Growth Rates in Defined Medium. BIOTECHNOLOGY AND BIOENGINEERING 2013
Journal Article
110 (1), pp. 220 - 228 (2013)
Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments. BIOTECHNOLOGY AND BIOENGINEERING 2012
Journal Article
12 (11), pp. 2060 - 8 (2012)
A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level. Lab Chip
Journal Article
11, 122 (2012)
Extensive exometabolome analysis reveals extended overflow metabolism in various microorganisms. MICROBIAL CELL FACTORIES
Journal Article
2 (4), pp. 1012 - 30 (2012)
Error propagation analysis for quantitative intracellular metabolomics. Metabolites Book Chapter (1)
2013
Book Chapter
Metabolomics in Biotechnology (Microbial Metabolomics). In: Metabolomics in Practice (2013)
Patent (3)
2020
Patent
Microfluidic system for yeast aging analysis. WO 2020/043786 A1 (2020)
2013
Patent
Vorrichtung und Verfahren zur Zellseparation. 102012009088 (2013)
Patent
Probeentnahmevorrichtung und Verfahren zur Entnahme einer Probe aus einem Bioreaktor. 102012003113 (2013)