Publications
2024
Preprint
Identification of EcpK, a bacterial tyrosine pseudokinase important for exopolysaccharide biosynthesis in Myxococcus xanthus. bioRxiv: the preprint server for biology, 2024.11.26.625375 (2024)
Journal Article
15 (1), 8898 (2024)
Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies. Nature Communications
Journal Article
A cell-free system for functional studies of small membrane proteins. Journal of Biological Chemistry, 107850 (2024)
Journal Article
Isofunctional but structurally different methyltransferases for dithiolopyrrolone diversification. Angewandte Chemie International Edition, e202410799 (2024)
Preprint
Expanding the biotechnological scope of metabolic sensors through computation-aided designs. bioRxiv: the preprint server for biology, 2024.08.23.609350 (2024)
Journal Article
15 (1), 7238 (2024)
Enhanced metabolic entanglement emerges during the evolution of an interkingdom microbial community. Nature Communications
Journal Article
15, 6829 (2024)
DEAD-box ATPase Dbp2 is the key enzyme in an mRNP assembly checkpoint at the 3'-end of genes and involved in the recycling of cleavage factors. Nature Communications
Journal Article
100 (9), fiae112 (2024)
Exploring modes of microbial interactions with implications for methane cycling. FEMS Microbiology Ecology
Journal Article
15 (1), 6014 (2024)
A deterministic, c-di-GMP-dependent program ensures the generation of phenotypically similar, symmetric daughter cells during cytokinesis. Nature Communications
Journal Article
385 (6705), pp. 174 - 178 (2024)
Integrated translation and metabolism in a partially self-synthesizing biochemical network. Science
Journal Article
15 (8), e0152424 (2024)
Multiple levels of transcriptional regulation control glycolate metabolism in Paracoccus denitrificans. mBio
Preprint
Promiscuous NAD-dependent dehydrogenases enable efficient bacterial growth on the PET monomer ethylene glycol. bioRxiv: the preprint server for biology, 2024.06.28.601223 (2024)
Preprint
Yersinia actively downregulates type III secretion and adhesion at higher cell densities. bioRxiv, 2024.06.27.601021 (2024)
Journal Article
13 (5), e12447 (2024)
Lipid A in outer membrane vesicles shields bacteria from polymyxins. Journal of extracellular vesicles
Journal Article
7 (1), 519 (2024)
Rationally designed chromosome fusion does not prevent rapid growth of Vibrio natriegens. Communications Biology
Journal Article
3, 100067 (2024)
The Type VI secretion systems of the insect pathogen Photorhabdus luminescens are involved in interbacterial competition, motility and secondary metabolism. The Microbe
Journal Article
10, 30 (2024)
Enhanced assembly of bacteriophage T7 produced in cell-free reactions under simulated microgravity. npj Microgravity
Journal Article
15 (3), e0331423 (2024)
Two distinct ferredoxins are essential for nitrogen fixation by the iron nitrogenase in Rhodobacter capsulatus. mBio
Preprint
DEAD-box ATPase Dbp2 mediates mRNA release after 3'-end formation. bioRxiv: the preprint server for biology, 2024.02.17.580811 (2024)
Preprint
Identification, structure and function of the methyltransferase involved in the biosynthesis of the dithiolopyrrolone antibiotic xenorhabdin. bioRxiv: the preprint server for biology, 2024.01.12.575338 (2024)
Journal Article
121, pp. 304 - 323 (2024)
Pilotins are mobile T3SS components involved in assembly and substrate specificity of the bacterial type III secretion system. Molecular Microbiology
Journal Article
13, RP93004 (2024)
A conserved cell-pole determinant organizes proper polar flagellum formation. eLife
Journal Article
15 (1), 318 (2024)
The virulence regulator VirB from Shigella flexneri uses a CTP-dependent switch mechanism to activate gene expression. Nature Communications
Book Chapter
2721, pp. 197 - 211 (Ed. Bertoni, G.) (2024)
In-depth quantitative proteomics analysis of the Pseudomonas aeruginosa secretome. In: Pseudomonas aeruginosa. Methods in Molecular Biology, Vol.
Journal Article
9, pp. 185 - 199 (2024)
Cytosolic sorting platform complexes shuttle type III secretion system effectors to the injectisome in Yersinia enterocolitica. Nature Microbiology 2023
Journal Article
4 (4), 102657 (2023)
A miniTurbo-based proximity labeling protocol to identify conditional protein interactomes in vivo in Myxococcus xanthus. STAR Protocols
Preprint
An interdependent metabolic and genetic network shows emergent properties in vitro. bioRxiv: the preprint server for biology, 2023.11.26.568713 (2023)
Book Chapter
2721, pp. 197 - 211 (Eds. Bertoni, G.; Ferrara, S.). Humana New York, NY (2023)
In-depth quantitative proteomics analysis of the Pseudomonas aeruginosa secretome. In: Pseudomonas aeruginosa: Methods and Protocols in Methods in Molecular Biology, Vol.
Preprint
Purine nucleotide limitation undermines antibiotic action in clinical Escherichia coli. bioRxiv: the preprint server for biology, 2023.06.22.546106 (2023)
Journal Article
14, 1205257 (2023)
Repertoire and abundance of secreted virulence factors shape the pathogenic capacity of Pseudomonas syringae pv. aptata. Frontiers in Microbiology
Journal Article
19 (6), e1010819 (2023)
During heat stress in Myxococcus xanthus, the CdbS PilZ domain protein, in concert with two PilZ-DnaK chaperones, perturbs chromosome organization and accelerates cell death. PLOS Genetics
Journal Article
89 (6), e0011323 (2023)
Asparagine uptake: a cellular strategy of Methylocystis to combat severe salt stress. Applied and Environmental Microbiology
Journal Article
76, pp. 97 - 109 (2023)
Implementation of the β-hydroxyaspartate cycle increases growth performance of Pseudomonas putida on the PET monomer ethylene glycol. Metabolic Engineering
Journal Article
14 (1), 4095 (2023)
DipM controls multiple autolysins and mediates a regulatory feedback loop promoting cell constriction in Caulobacter crescentus. Nature Communications
Journal Article
13, 166077 (2023)
A ParDE toxin–antitoxin system is responsible for the maintenance of the Yersinia virulence plasmid but not for type III secretion-associated growth inhibition. Frontiers in Cellular and Infection Microbiology
Journal Article
24 (7), pp. 768 - 787 (2023)
Structural and functional analysis of the cerato-platanin-like protein Cpl1 suggests diverging functions in smut fungi. Molecular Plant Pathology
Journal Article
620 (7976), pp. 1054 - 1062 (2023)
A viral ADP-ribosyltransferase attaches RNA chains to host proteins. Nature 2022
Journal Article
14 (11), 2502 (2022)
Integrated omics reveal time-resolved insights into T4 phage infection of E. coli on proteome and transcriptome levels. Viruses
Preprint
Engineered synthetic one-carbon fixation exceeds yield of the Calvin Cycle. bioRxiv: the preprint server for biology, 2022.10.19.512895 (2022)
Journal Article
13 (5), e02032-22 (2022)
Evidence for a widespread third system for bacterial polysaccharide export across the outer membrane comprising a composite OPX/β-barrel translocon. mBio
Journal Article
7 (5), e0040322 (2022)
Methylocystis sp. strain SC2 acclimatizes to increasing NH4+ levels by a precise rebalancing of enzymes and osmolyte composition. mSystems
Journal Article
8, 35 (2022)
GGDEF domain as spatial on-switch for a phosphodiesterase by interaction with landmark protein HubP. npj Biofilms and Microbiomes
Journal Article
119 (6), e2115061119 (2022)
A noncanonical cytochrome c stimulates calcium binding by PilY1 for type IVa pili formation. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
11 (9), pp. 2989 - 3003 (2022)
An easy-to-use plasmid toolset for efficient generation and benchmarking of synthetic small RNAs in bacteria. ACS Synthetic Biology
Journal Article
118 (6), pp. 670 - 682 (2022)
FlrA-independent production of flagellar proteins is required for proper flagellation in Shewanella putrefaciens. Molecular Microbiology 2021
Journal Article
12 (1), 4929 (2021)
Metabolome and proteome analyses reveal transcriptional misregulation in glycolysis of engineered E. coli. Nature Communications
Preprint
Vibrio cholerae biofilm dispersal regulator causes cell release from matrix through type IV pilus retraction. bioRxiv: the preprint server for biology, 2021.05.02.442311 (2021)
Journal Article
12 (1), pp. 56 - 67.E6 (2021)
Multi-omics analysis of CRISPRi-knockdowns identifies mechanisms that buffer decreases of enzymes in E. coli metabolism. Cell Systems
Journal Article
231 (1), pp. 416 - 431 (2021)
A small Ustilago maydis effector acts as a novel adhesin for hyphal aggregation in plant tumors. New Phytologist
Journal Article
6, pp. 722 - 730 (2021)
A cell surface-exposed protein complex with an essential virulence function in Ustilago maydis. Nature Microbiology 2020
Journal Article
5 (12), pp. 1481 - 1489 (2020)
Symbiosis, virulence and natural-product biosynthesis in entomopathogenic bacteria are regulated by a small RNA. Nat Microbiol
Journal Article
86 (21), e01113-20 (2020)
Multiple Drug-Induced Stress Responses Inhibit Formation of Escherichia coli Biofilms. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Journal Article
11 (1), 5054 (2020)
PilY1 and minor pilins form a complex priming the type IVa pilus in Myxococcus xanthus. NATURE COMMUNICATIONS
Journal Article
22 (10), pp. 4279 - 4294 (2020)
Specific proteomic adaptation to distinct environments in Vibrio parahaemolyticus includes significant fluctuations in expression of essential proteins. ENVIRONMENTAL MICROBIOLOGY
Journal Article
11, 573260 (2020)
Isolation and Characterization ofShewanellaPhage Thanatos Infecting and LysingShewanella oneidensisand Promoting Nascent Biofilm Formation. FRONTIERS IN MICROBIOLOGY
Journal Article
61, pp. 181 - 196 (2020)
Hydrogen utilization by Methylocystis sp. strain SC2 expands the known metabolic versatility of type IIa methanotrophs. METABOLIC ENGINEERING
Journal Article
11 (1), 3494 (2020)
Design of a MAPK signalling cascade balances energetic cost versus accuracy of information transmission. NATURE COMMUNICATIONS
Journal Article
60, pp. 14 - 24 (2020)
High-throughput enrichment of temperature-sensitive argininosuccinate synthetase for two-stage citrulline production in E. coli. METABOLIC ENGINEERING
Journal Article
5 (3), pp. 395 - + (2020)
Transcriptional regulation by sigma factor phosphorylation in bacteria. NATURE MICROBIOLOGY
Journal Article
14 (1), pp. 230 - 244 (2020)
The release of a distinct cell type from swarm colonies facilitates dissemination of Vibrio parahaemolyticus in the environment. ISME JOURNAL
Journal Article
19 (1), pp. 543 - 553 (2020)
A Serial Sample Processing Strategy with Improved Performance for in-Depth Quantitative Analysis of Type III Secretion Events in Pseudomonas aeruginosa. JOURNAL OF PROTEOME RESEARCH 2019
Journal Article
575 (7783), pp. 500 - + (2019)
Marine Proteobacteria metabolize glycolate via the β-hydroxyaspartate cycle. NATURE
Journal Article
19 (20), 1900136 (2019)
Efficient Tandem LysC/Trypsin Digestion in Detergent Conditions. PROTEOMICS
Journal Article
8 (9), pp. 1983 - 1990 (2019)
CRISPRi-Based Downregulation of Transcriptional Feedback Improves Growth and Metabolism of Arginine Overproducing E. coli. ACS SYNTHETIC BIOLOGY
Journal Article
10, 793 (2019)
Structural and Proteomic Changes in Viable but Non-culturable Vibrio cholerae. FRONTIERS IN MICROBIOLOGY
Journal Article
10, 1360 (2019)
A TonB-dependent transporter is required for secretion of protease PopC across the bacterial outer membrane. NATURE COMMUNICATIONS
Journal Article
73 (3), pp. 413 - + (2019)
RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation. MOLECULAR CELL
Journal Article
565 (7741), pp. 650 - + (2019)
A kiwellin disarms the metabolic activity of a secreted fungal virulence factor. NATURE
Journal Article
16, pp. 145 - + (2019)
Inefficient Secretion of Anti-sigma Factor FlgM Inhibits Bacterial Motility at High Temperature. ISCIENCE
Journal Article
8 (1), pp. 66 - + (2019)
Allosteric Feedback Inhibition Enables Robust Amino Acid Biosynthesis in E-coli by Enforcing Enzyme Overabundance. CELL SYSTEMS
Journal Article
17 (1), 90 (2019)
Palmitoylation is required for TNF-R1 signaling. CELL COMMUNICATION AND SIGNALING 2018
Journal Article
23 (2), pp. 470 - 484 (2018)
Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential. CELL REPORTS
Journal Article
109 (3), pp. 365 - 384 (2018)
A cell length-dependent transition in MinD-dynamics promotes a switch in division-site placement and preservation of proliferating elongated Vibrio parahaemolyticus swarmer cells. MOLECULAR MICROBIOLOGY
Journal Article
47, pp. 423 - 433 (2018)
An engineered Calvin-Benson-Bassham cycle for carbon dioxide fixation in Methylobacterium extorquens AM1. METABOLIC ENGINEERING
Journal Article
115 (52), pp. 13365 - 13370 (2018)
Baseplate variability of Vibrio cholerae chemoreceptor arrays. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2017
Journal Article
114 (50), pp. E10792 - E10798 (2017)
Osmosensing by the bacterial PhoQ/PhoP two-component system. Proceedings of the National Academy of Sciences of the United States of America
Book Chapter
Pull-Down with a c-di-GMP-Specific Capture Compound Coupled to Mass Spectrometry as a Powerful Tool to Identify Novel Effector Proteins. In: C-DI-GMP SIGNALING: Methods and Protocols, pp. 361 - 376 (2017)
2016
Journal Article
15 (8), pp. 2537 - 2547 (2016)
Evaluation and Improvement of Quantification Accuracy in Isobaric Mass Tag-Based Protein Quantification Experiments. JOURNAL OF PROTEOME RESEARCH
Journal Article
44 (6), pp. 1312 - 1324 (2016)
Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function. IMMUNITY
Journal Article
15 (2), p. 679 - 679 (2016)
Comparison of Different Sample Preparation Protocols Reveals Lysis Buffer-Specific Extraction Biases in Gram-Negative Bacteria and Human Cells (vol 14, pg 4472, 2015). JOURNAL OF PROTEOME RESEARCH
Journal Article
13 (7), pp. 2290 - 2300 (2016)
Secreted Matrix Metalloproteinase-9 of Proliferating Smooth Muscle Cells as a Trigger for Drug Release from Stent Surface Polymers in Coronary Arteries. MOLECULAR PHARMACEUTICS
Journal Article
17 (2), pp. 583 - 595 (2016)
A High-Density Map for Navigating the Human Polycomb Complexome. CELL REPORTS
Journal Article
23 (12), pp. 2019 - 2030 (2016)
The de-ubiquitylating enzyme DUBA is essential for spermatogenesis in Drosophila. CELL DEATH AND DIFFERENTIATION
Journal Article
198 (1), pp. 127 - 137 (2016)
An Extended Cyclic Di-GMP Network in the Predatory Bacterium Bdellovibrio bacteriovorus. JOURNAL OF BACTERIOLOGY 2015
Journal Article
5, pp. 297 - 304 (2015)
Assessment of current mass spectrometric workflows for the quantification of low abundant proteins and phosphorylation sites. Data in Brief
Journal Article
128 (9), pp. 1674 - 1682 (2015)
The E3 ubiquitin ligase Mib1 regulates Plk4 and centriole biogenesis. JOURNAL OF CELL SCIENCE
Journal Article
14 (11), pp. 4472 - 4485 (2015)
Comparison of Different Sample Preparation Protocols Reveals Lysis Buffer-Specific Extraction Biases in Gram-Negative Bacteria and Human Cells. JOURNAL OF PROTEOME RESEARCH
Journal Article
12 (9), pp. 1497 - 1507 (2015)
Adenylylation of Gyrase and Topo IV by FicT Toxins Disrupts Bacterial DNA Topology. CELL REPORTS
Journal Article
Capture Compound Mass Spectrometry - A Powerful Tool to Identify Novel c-di-GMP Effector Proteins. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (97), e51404 (2015)
2014
Journal Article
13 (12), pp. 5973 - 5988 (2014)
Evaluation of Data-Dependent and -Independent Mass Spectrometric Workflows for Sensitive Quantification of Proteins and Phosphorylation Sites. JOURNAL OF PROTEOME RESEARCH
Journal Article
7 (5), pp. 1426 - 1433 (2014)
The Central Metabolism Regulator EIIA(Glc) Switches Salmonella from Growth Arrest to Acute Virulence through Activation of Virulence Factor Secretion. CELL REPORTS
Journal Article
14 (9), pp. 1048 - 1052 (2014)
An experimental strategy for the identification of AMPylation targets from complex protein samples. PROTEOMICS 2013
Journal Article
13 (17), pp. 2567 - 2578 (2013)
Critical assessment of proteome-wide label-free absolute abundance estimation strategies. PROTEOMICS
Journal Article
20 (3), pp. 347 - 354 (2013)
Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition. NATURE STRUCTURAL & MOLECULAR BIOLOGY 2012
Journal Article
11 (4), pp. 2619 - 2624 (2012)
SAINT-MS1: Protein-Protein Interaction Scoring Using Label-free Intensity Data in Affinity Purification-Mass Spectrometry Experiments. JOURNAL OF PROTEOME RESEARCH
Journal Article
11 (11), pp. 5145 - 5156 (2012)
Large-Scale Quantitative Assessment of Different In-Solution Protein Digestion Protocols Reveals Superior Cleavage Efficiency of Tandem Lys-C/Trypsin Proteolysis over Trypsin Digestion. JOURNAL OF PROTEOME RESEARCH
Journal Article
75 (15), pp. 4874 - 4878 (2012)
A novel capture compound for the identification and analysis of cyclic di-GMP binding proteins. JOURNAL OF PROTEOMICS 2011
Journal Article
7, 547 (2011)
Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome. MOLECULAR SYSTEMS BIOLOGY
Journal Article
147 (7), pp. 1601 - 1614 (2011)
SAM68 Regulates Neuronal Activity-Dependent Alternative Splicing of Neurexin-1. CELL