Microbial interactions from a molecular and evolutionary perspective

SFB Mini Symposium

  • Date: Apr 11, 2016
  • Time: 14:15
  • Speaker: Dr. Olaya Rendueles-Garcia
  • Microbial Evolutionary Genomics, Institut Pasteur, Paris
  • Location: MPI for Terrestrial Microbiology
  • Room: Lecture hall
  • Host: SFB 987
  • Contact: Nelli.Melcher@sfb987.de

Antagonistic bacterial interactions are common in biofilms where bacteria compete for limited space and nutrients. These interactions are conditioned by a number of factors related to the biofilm lifestyle like group effects, high intrinsic genetic – and phenotypic – diversity, strong kin competition and cooperation.

Whereas research on competitive interactions mostly focused in the characterization of antibiotic-like compounds, more recently a myriad of non-biocidal antagonistic molecules have been identified and the underlying molecular mechanisms have been characterized. Yet how microorganisms adapt and outcompete their conspecific neighbors in multispecies and high cell-density environments remains poorly studied.

After providing a brief overview of the diverse competition mechanisms within biofilms, I will focus on antibiofilm polysaccharides and their role in population dynamics. Finally, I will discuss adaptation mechanisms, including de novo emergence of interference competition, during long-term experimental evolution using soil-dwelling Myxococcus xanthus as a model organism.
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