The predation strategy of Myxococcus xanthus

Microbiology Seminar Series

  • Date: Apr 4, 2022
  • Time: 01:15 PM (Local Time Germany)
  • Speaker: Dr. Christine Kaimer
  • Ruhr Universität Bochum, Department for Biology and Biotechnology, Microbial Biology
  • Location: MPI for Terrestrial Microbiology
  • Room: Lecture hall
  • Host: Dr. Andreas Diepold
  • Contact:

Predation shapes interbacterial interactions in different habitats, but we know little about its molecular mechanisms. We investigate predation mechanisms in the myxobacterium Myxococcus xanthus, which feeds on a broad range of microorganisms in soil.

Comparing different bacteriolytic properties of M. xanthus, we found that an unkown, cell-contact dependent mechanism is used to kill Gram positive and Gram negative bacteria. This involves the concerted action of two protein secretion systems, which accumulate at the predator-prey interface. These secretion systems mediate cell death and lysis, respectively, and are both required for M. xanthus to extract nutrients from prey.

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