Graduate Students Mini Symposium V 2020 (virtual meeting)

  • Date: Apr 20, 2020
  • Time: 13:00
  • Location: MPI for Terrestrial Microbiology
  • Room: -
  • Host: IMPRS
  • Contact: imprs@mpi-marburg.mpg.de

Program:

13:00 Eric Jelli, AG Drescher

Developing a robust and versatile imaging analysis toolbox for cell segmentation inside bacterial biofilms

Due to the low signal-to-noise ratio and the large number of densely packed cells, the analysis of 3-dimensional bacterial biofilms remains a challenging task. While manually tuned pipelines can produce high-quality results for single projects, a general tool for the extraction of single-cell biofilm data is missing. Driven by the needs of our lab, we created an all-in-one analysis program, which can be used for the analysis of a large number of biofilm experiments. Due to the widely applicable base pipeline, the new program effectively shortens the time from experiment to analysis results and minimizes the adaptation time in new projects. Initially limited to a pseudo-cell segmentation, the program can now produce robust single-cell segmentation for biofilm experiments.


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