Susanne Kneip


Main Focus


Elucidation of signal transduction pathways and networks that control development, motility, cell polarity and cell cycle in Myxococcus xanthus by using various techniques in cell biology, molecular biology, protein biochemistry, biophysics and theoretical modelling.



Development of a modern and state-of-the-art research environment

Creative problem solving

Helping staff to achieve their scientific goals

Managing budgets

Coordinate, monitor and organize routine labwork and maintenance services completion

Event management



Huntley S, Kneip S, Treuner-Lange A, Søgaard-Andersen L.

Complete genome sequence of Myxococcus stipitatus strain DSM 14675, a fruiting myxobacterium.

Genome Announc. 2013 Mar 21;1(2):e0010013. doi: 10.1128/genomeA.00100-13.


Huntley S, Zhang Y, Treuner-Lange A, Kneip S, Sensen CW, Søgaard-Andersen L.

Complete genome sequence of the fruiting myxobacterium Corallococcus coralloides DSM 2259.

J Bacteriol. 2012 Jun;194(11):3012-3. doi: 10.1128/JB.00397-12.


Zuccaro A*, Götze S*, Kneip S*, Dersch P, Seibel J.

Tailor-made fructooligosaccharides by a combination of substrate and genetic engineering.

Chembiochem. 2008 Jan 4;9(1):143-9. (* Equally 

contributing authors)


Schiefner A, Breed J, Bösser L, Kneip S, Gade J, Holtmann G, Diederichs K, Welte W, Bremer E.

Cation-pi interactions as determinants for binding of the compatible solutes glycine betaine and proline betaine by the periplasmic ligand-binding protein ProX from Escherichia coli.

J Biol Chem. 2004 Feb 13;279(7):5588-96. Epub 2003 Nov 11.


Csepregi A, Obermayer-Straub P, Kneip S, Kayser A, Loges S, Schmidt E, Nemesánszky E, Szalay F, Manns MP, Strassburg CP.

Characterization of a lipoyl domain-independent B-cell autoepitope on the human branched-chain acyltransferase in primary biliary cirrhosis and overlap syndrome with autoimmune hepatitis.

Clin Dev Immunol. 2003 Jun-Dec;10(2-4):173-81.


Strassburg CP, Vogel A, Kneip S, Tukey RH, Manns MP.

Polymorphisms of the human UDP-glucuronosyltransferase (UGT) 1A7 gene in colorectal cancer.

Gut. 2002 Jun;50(6):851-6.


Strassburg CP, Strassburg A, Kneip S, Barut A, Tukey RH, Rodeck B, Manns MP.

Developmental aspects of human hepatic drug glucuronidation in young children and adults.

Gut. 2002 Feb;50(2):259-65.


Vogel A, Kneip S, Barut A, Ehmer U, Tukey RH, Manns MP, Strassburg CP.

Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene.

Gastroenterology. 2001 Nov;121(5):1136-44. Erratum in: Gastroenterology. 2011 May;140(5):1696.


Breed J, Kneip S, Gade J, Welte W, Bremer E.

Purification, crystallization and preliminary crystallographic analysis of the periplasmic binding protein ProX from Escherichia coli.

Acta Crystallogr D Biol Crystallogr. 2001 Mar;57(Pt 3):448-50.


Strassburg CP, Kneip S, Topp J, Obermayer-Straub P, Barut A, Tukey RH, Manns MP.

Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine.

J Biol Chem. 2000 Nov 17;275(46):36164-71.


Cánovas D, Vargas C, Kneip S, Morón MJ, Ventosa A, Bremer E, Nieto JJ.

Genes for the synthesis of the osmoprotectant glycine betaine from choline in the moderately halophilic bacterium Halomonas elongata DSM 3043, USA.

Microbiology. 2000 Feb;146 ( Pt 2):455-63.


Kappes RM, Kempf B, Kneip S, Boch J, Gade J, Meier-Wagner J, Bremer E.

Two evolutionarily closely related ABC transporters mediate the uptake of choline for synthesis of the osmoprotectant glycine betaine in Bacillus subtilis.

Mol Microbiol. 1999 Apr;32(1):203-16.


Boch J, Nau-Wagner G, Kneip S, Bremer E.

Glycine betaine aldehyde dehydrogenase from Bacillus subtilis: characterization of an enzyme required for the synthesis of the osmoprotectant glycine betaine.

Arch Microbiol. 1997 Oct;168(4):282-9.


Calamita G, Kempf B, Rudd KE, Bonhivers M, Kneip S, Bishai WR, Bremer E, Agre P.

The aquaporin-Z water channel gene of Escherichia coli: structure, organization and phylogeny.

Biol Cell. 1997 Aug;89(5-6):321-9.


Herbst B, Kneip S, Bremer E.

pOSEX: vectors for osmotically controlled and finely tuned gene expression in Escherichia coli.

Gene. 1994 Dec 30;151(1-2):137-42.


Dersch P, Kneip S, Bremer E.

The nucleoid-associated DNA-binding protein H-NS is required for the efficient adaptation of Escherichia coli K-12 to a cold environment.

Mol Gen Genet. 1994 Oct 28;245(2):255-9.


Beckh K, Kneip S, Arnold R.

Direct regulation of bile secretion by prostaglandins in perfused rat liver.

Hepatology. 1994 May;19(5):1208-13.

Curriculum Vitae


1/2010 - today

Max Planck Institute for Terrestrial Microbiology, Department of Ecophysiology, Marburg.


Technical Assistant


1/2008 - 12/2009

Max Planck Institute for Terrestrial Microbiology, Department of Ecophysiology, working group "Bacterial adaption and differentiation", Marburg.


01/2002 – 12/2007

Technische Universität Braunschweig, Institute of Microbiology, Collaborative Research Center SFB578 "From Gene to Product" and Department of Infection Biology.

01/1999 - 12/2001 

Hannover Medical School, Medical Center for Gastroenterology, Hepatology and Endocrinology, working group "human UDP-glucuronosyltransferases".


1/1996 – 12/1998 

Philipps University Marburg, Faculty of Biology, Laboratory of Microbiology, working group "Stress responses of the soil bacterium Bacillus subtilis to changing osmolarity.


9/1992 – 1/1996 

Max Planck Institute for Terrestrial Microbiology, working group "Stress responses of the soil bacterium Bacillus subtilis to changing osmolarity", Marburg.


11/1987 – 3/1992 

Philipps University Marburg, Medical Centre for Internal Medicine, Department for Digestive and Metabolic Diseases,  working groups Hepatology and Neurogastroenterology.


10/1985 – 10/1987 

School for Medical Technical Assistants, Philipps University Marburg 

State examination as Medical Technical Assistant

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