Regulation of mitochondrial morphology during sexual development of Ustilago maydis
Research report (imported) 2006 - Max Planck Institute for Terrestrial Microbiology
Sexual development of the phytopathogenic fungus Ustilago maydis is governed by the mating type loci a and b. The a2 locus genes lga2 and rga2 encode mitochondrial proteins, whose expression is coupled to the sexual cycle. These proteins compromise mitochondrial integrity and pathogenesis in the absence of the mitochondrial p32 family protein Mrb1. Lga2 interferes with mitochondrial fusion and together with Rga2 has a possible function in controlling mitochondrial inheritance.