Publications

Gomez-Escribano, J. P., Gallardo, L. A., Bozhüyük, K. A. J., Kendrew, S. G., Huckle, B. D., Crowhurst, N. A., Bibb, M. J., Collis, A. J., Micklefield, J., Herron, P. R. and Wilkinson, B. (2021)
Genome editing reveals that pSCL4 is required for chromosome linearity in Streptomyces clavuligerus, Microb Genom. 7(11). doi: 10.1099/mgen.0.000669

Bozhüyük, K., Watzel, J., Abbood, N. and Bode, H. B. (2021)
Synthetic Zippers as an Enabling Tool for Engineering of Non-Ribosomal Peptide Synthetases. Angew Chem Int Ed Engl. 60(32), 17531-17538. doi: 10.1002/anie.202102859

Bozhüyük, K. A. J., Micklefield, J. and Wilkinson, B. (2019)
Engineering Enzymatic Assembly Lines to Produce New Antibiotics. Curr. Opin. Microbiol., 51, 88–96. doi: 10.1016/j.mib.2019.10.007.

Bozhüyük, K. A. J., Linck, A., Tietze, A., Kranz, J., Wesche, F., Nowak, S., Fleischhacker, F., Shi, Y. N., Grün, P. and Bode, H. B. (2019)
Modification and de novo design of non-ribosomal peptide synthetases using specific assembly points within condensation domains. Nat. Chem. 11 (7), 653-661. doi: 10.1038/s41557-019-0276-z.

Bozhüyük, K. A. J., Fleischhacker, F., Linck, A., Wesche, F., Tietze, A., Niesert, C.-P. and Bode, H. B. (2018)
De novo design and engineering of non-ribosomal peptide synthetases. Nat. Chem. 10(3), 275-281. doi: 10.1038/nchem.2890.

Bozhüyük, K. A., Zhou, Q., Engel, Y., Heinrich, A., Pérez, A. and Bode, H. B. (2017)
Natural products from Photorhabdus and other entomopathogenic bacteria. Curr. Top Microbiol, Immunol. 402, 55-79. doi: 10.1007/82_2016_24.

Nollmann, F. I., Heinrich, A. K., Brachmann, A. O., Morisseau, C., Mukherjee, K., Casanova-Torres, Á. M., Strobl, F., Kleinhans, D., Kinski, S., Schultz, K., Beeton, M. L., Kaiser, M., Chu, Y. Y., Phan Ke, L.,  Ke, Thanwisai, A., Bozhüyük, K. A. J., Chantratita, N., Götz, F., Waterfield, N. R., Vilcinskas, A., Stelzer, E., Goodrich-Blair, H., Hammock, B. D. and Bode, H. B. (2015)
Photorhabdus natural product inhibits insect juvenile hormone epoxide hydrolase. Chem. Bio. Chem. 16, 766-771. doi: 10.1002/cbic.201402650.

Kronenwerth, M., Bozhüyük, K. A. J., Kahnt, A. S., Steinhilber, D., Gaudriault, S., Kaiser, M. and Bode, H. B. (2014)
Characterisation of taxlllaids A-G; natural products from Xenorhabdus indica. Chem. Eur. J. 20, 17478-17487. doi: 10.1002/chem.201403979.

Lorenzen, W., Bozhüyük, K. A. J., Cortina, N. S. and Bode, H. B. (2014)
A comprehensive insight into the lipid composition of Myxococcus xanthus by UPLC-ESI-MS. J. Lipid Res. 55, 2620-2633. doi: 10.1194/jlr.M054593.

Lorenzen, W., Ahrendt, T., Bozhüyük, K. A. J. and Bode, H. B. (2014)
A multifunctional enzyme is involved in bacterial ether lipid biosynthesis. Nat. Chem. Biol. 10, 425-427. doi: 10.1038/nchembio.1526.

Fuchs, S.W., Bozhüyük, K. A. J., Kresovic, D., Grundmann, F., Dill, V., Brachmann, A. O., Waterfield, N.R. and Bode, H. B. (2013)
Formation of 1,3-Cyclohexanediones and Resorcinols Catalyzed by a Widely Occuring Ketosynthase. Angew. Chem. Int. Ed. 52, 4108-4112. doi: 10.1002/anie.201210116

 

Preprints

Booth, T. J., Bozhüyük, K. A. J., Liston, J. D., Lacey, E. and Wilkinson, B. (2021)
Bifurcation drives the evolution of assembly-line biosynthesis. preprint (biorxiv). doi: 10.1101/2021.06.23.449585.

Kranz, J., Wenski, S., Dichter, A. A., Bode, H. B. and Bozhüyük, K. A. J. (2021)
Influence of condensation domains on activity and specificity of adenylation domains. preprint (biorxiv). doi: 10.1101/2021.08.23.457306.

Abbood, N., Vo, T. D., Watzel, J., Bozhüyük, K. A. J. and Bode, H. B. (2021)
Type S Non-Ribosomal Peptide Synthetases for the rapid generation of tailor-made peptide libraries. preprint (biorxiv). doi: 10.1101/2021.10.25.465728

 

Patents

Niesert, C. P., Bode, H. B., Bozhüyük, K. A. J. and Fleischhacker, F. (2017)
Artificial non-ribosomal peptide synthetases, WO2017020983(A1).

 

Additional Publications (not peer-reviewed)

Bozhüyük, K. A. J. & Bode, H. B. (2018)
Innovative Anti-Infectives – Synthetic Biology for the Production of Complex Peptides. Published on CHEMManager International (https://www.chemanager-online.com). Publishing Date: 19.09.2018

Bozhüyük, K. A. J. & Bode, H. B. (2018)
Wirkstoff-Forschung: Herstellung maßgeschneiderter komplexer Peptide. Published on GIT-Labor – Portal für Anwender in Wissenschaft und Industrie (https://www.git-labor.de). Publishing Date: 06.02.2018

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