Publications of Nicole Paczia

Guo, K., Hakobyan, A., Glatter, T., Paczia, Nicole and Liesack, W.: (2022) Methylocystis sp. strain SC2 acclimatizes to increasing NH₄⁺ levels by a precise rebalancing of enzymes and osmolyte composition, mSystems, American Society for Microbiology, 7 (5).

Pandi, A., Diehl, C., Yazdizadeh Kharrazi, A., Scholz, S. A., Bobkova, E., Faure, L., Nattermann, M., Adam, D., Chapin, N., Foroughijabbari, Y., Moritz, C., Paczia, N., Cortina, N. S., Faulon, J. L. and Erb, T. J.: (2022) A versatile active learning workflow for optimization of genetic and metabolic networks, Nature Communications, London, Nature Publishing Group, 13 (1).

Danileviciute, Egle, Zeng, Ni, Capelle, Christophe M., Paczia, Nicole, Gillespie, Mark A., Kurniawan, Henry, Benzarti, Mohaned, Merz, Myriam P., Coowar, Djalil, Fritah, Sabrina, Weisenhorn, Vogt, Maria, Daniela, Gomez Giro, Gemma, Grusdat, Melanie, Baron, Alexandre, Guerin, Coralie, Franchina, Davide G., Léonard, Cathy, Domingues, Olivia, Delhalle, Sylvie, Wurst, Wolfgang, Turner, Jonathan D., Schwamborn, Jens Christian, Meiser, Johannes, Krüger, Rejko, Ranish, Jeff, Brenner, Dirk, Linster, Carole L., Balling, Rudi, Ollert, Markus and Hefeng, Feng Q.: (2022) PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing, Nature Metabolism, London, Springer Nature, 4 (5), pp. 589–607.

Schaupp, S., Arriaza Gallardo, F. J., Pan, H. J., Kahnt, J., Angelidou, G., Paczia, N., Costa, K., Hu, X. and Shima, S.: (2022) In vitro biosynthesis of the [Fe]-hydrogenase cofactor verifies the proposed biosynthetic precursors, Angewandte Chemie, International Edition in English, Weinheim, Wiley-VCH, 61 (22).

Nattermann, M., Burgener, S., Pfister, P., Chou, A., Schulz, L., Lee, S. H., Paczia, Nicole, Zarzycki, J., Gonzalez, R. and Erb, T. J.: (2021) Engineering a highly efficient carboligase for synthetic one-carbon metabolism, ACS Catalysis, Washington, DC, ACS, 11 (9), pp. 5396–5404.

Castaneda-Losada, L., Adam, D., Paczia, N., Buesen, D., Steffler, F., Sieber, V., Erb, T. J., Richter, M. and Plumere, N.: (2021) Bioelectrocatalytic cofactor regeneration coupled to CO₂ fixation in a redox-active hydrogel for stereoselective C-C bond formation, Angewandte Chemie, International Edition in English, Weinheim, Wiley-VCH, 60 (38), pp. 21056–21061.

Sundaram, S., Diehl, C., Cortina, N. S., Bamberger, J., Paczia, N. and Erb, T. J.: (2021) A modular in vitro platform for the production of terpenes and polyketides from CO₂, Angewandte Chemie, International Edition in English, Weinheim, Wiley-VCH, 60 (30), pp. 16420–16425.

Roell, Marc-Sven, Schada von Borzykowski, Lennart, Westhoff, Philipp, Plett, Anastasija, Paczia, Nicole, Claus, Peter, Urte, Schlueter, Erb, Tobias J. and Weber, Andreas P M: (2021) A synthetic C4 shuttle via the beta-hydroxyaspartate cycle in C3 plants., Proceedings of the National Academy of Sciences of the United States of America, Washington, D.C., National Academy of Sciences, 118 (21).

Hakobyan, Anna, Zhu, Jing, Glatter, Timo, Paczia, Nicole and Liesack, Werner: (2020) Hydrogen utilization by Methylocystis sp. strain SC2 expands the known metabolic versatility of type IIa methanotrophs, METABOLIC ENGINEERING, 61, September, pp. 181–196.

Cotton, Charles A. R., Bernhardsgrütter, Iria, He, Hai, Burgener, Simon, Schulz, Luca, Paczia, Nicole, Dronsella, Beau, Erban, Alexander, Toman, Stepan, Dempfle, Marian, De Maria, Alberto, Kopka, Joachim, Lindner, Steffen N., Erb, Tobias J. and Bar-Even, Arren: (2020) Underground isoleucine biosynthesis pathways in E. coli, ELIFE, 9, August.

Milne-Davies, Bailey, Helbig, Carlos, Wimmi, Stephan, Cheng, Dorothy W. C., Paczia, Nicole and Diepold, Andreas: (2019) Life After Secretion-Yersinia enterocolitica Rapidly Toggles Effector Secretion and Can Resume Cell Division in Response to Changing External Conditions, FRONTIERS IN MICROBIOLOGY, 10, September.

Paczia, Nicole, Becker-Kettern, Julia, Conrotte, Jean-Francois, Cifuente, Javier O., Guerin, Marcelo E. and Linster, Carole L.: (2019) 3-Phosphoglycerate Transhydrogenation Instead of Dehydrogenation Alleviates the Redox State Dependency of Yeast de Novo L-Serine Synthesis, SI, 58 (4), pp. 259–275.

Schymanski, Emma L., Baker, Nancy C., Williams, Antony J., Singh, Randolph R., Trezzi, Jean-Pierre, Wilmes, Paul, Kolber, Pierre L., Kruger, Rejko, Paczia, Nicole, Linster, Carole L. and Balling, Rudi: (2019) Connecting environmental exposure and neurodegeneration using cheminformatics and high resolution mass spectrometry: potential and challenges, ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS, 21 (9), pp. 1426–1445.

Van Bergen, Nicole J., Guo, Yiran, Rankin, Julia, Paczia, Nicole, Becker-Kettern, Julia, Kremer, Laura S., Pyle, Angela, Conrotte, Jean-Francois, Ellaway, Carolyn, Procopis, Peter, Prelog, Kristina, Homfray, Tessa, Baptista, Julia, Baple, Emma, Wakeling, Matthew, Massey, Sean, Kay, Daniel P., Shukla, Anju, Girisha, Katta M., Lewis, Leslie E. S., Santra, Saikat, Power, Rachel, Daubeney, Piers, Montoya, Julio, Ruiz-Pesini, Eduardo, Kovacs-Nagy, Reka, Pritsch, Martin, Ahting, Uwe, Thorburn, David R., Prokisch, Holger, Taylor, Robert W., Christodoulou, John, Linster, Carole L., Ellard, Sian and Hakonarson, Hakon: (2019) NAD(P)HX dehydratase (NAXD) deficiency: a novel neurodegenerative disorder exacerbated by febrile illnesses, BRAIN, 142, pp. 50–58.

Veiga-da-Cunha, Maria, Chevalier, Nathalie, Stephenne, Xavier, Defour, Jean-Philippe, Paczia, Nicole, Ferster, Alina, Achouri, Younes, Dewulf, Joseph P., Linster, Carole L., Bommer, Guido T. and Van Schaftingen, Emile: (2019) Failure to eliminate a phosphorylated glucose analog leads to neutropenia in patients with G6PT and G6PC3 deficiency, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116 (4), pp. 1241–1250.

Becker-Kettern, Julia, Paczia, Nicole, Conrotte, Jean-Francois, Zhu, Chenchen, Fiehn, Oliver, Jung, Paul P., Steinmetz, Lars M. and Linster, Carole L.: (2018) NAD(P)HX repair deficiency causes central metabolic perturbations in yeast and human cells, FEBS JOURNAL, 285 (18), pp. 3376–3401.

Berger, Emanuel, Magliaro, Chiara, Paczia, Nicole, Monzel, Anna S., Antony, Paul, Linster, Carole L., Bolognin, Silvia, Ahluwalia, Arti and Schwamborn, Jens C.: (2018) Millifluidic culture improves human midbrain organoid vitality and differentiation, LAB ON A CHIP, 18 (20), pp. 3172–3183.

Jung, Paul P., Zhang, Zhi, Paczia, Nicole, Jaeger, Christian, Ignac, Tomasz, May, Patrick and Linster, Carole L.: (2018) Natural variation of chronological aging in the Saccharomyces cerevisiae species reveals diet-dependent mechanisms of life span control, NPJ AGING AND MECHANISMS OF DISEASE, 4.

Peracchi, Alessio, Veiga-da-Cunha, Maria, Kuhara, Tomiko, Ellens, Kenneth W., Paczia, Nicole, Stroobant, Vincent, Seliga, Agnieszka K., Marlaire, Simon, Jaisson, Stephane, Bommer, Guido T., Sun, Jin, Huebner, Kay, Linster, Carole L., Cooper, Arthur J. L. and van Schaftingen, Emile: (2017) Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114 (16), pp. E3233–E3242.

Becker-Kettern, Julia, Paczia, Nicole, Conrotte, Jean-Francois, Kay, Daniel P., Guignard, Cedric, Jung, Paul P. and Linster, Carole L.: (2016) Saccharomyces cerevisiae Forms d-2-Hydroxyglutarate and Couples Its Degradation to d-Lactate Formation via a Cytosolic Transhydrogenase, JOURNAL OF BIOLOGICAL CHEMISTRY, 291 (12), pp. 6036–6058.