Graduate Students Mini-Symposium

Robust Population control in Synthetic Communities

  • Date: Mar 13, 2017
  • Time: 13:50
  • Speaker: Anne Löchner
  • MPI / Systems and Synthetic Microbiology
  • Location: MPI for Terrestrial Microbiology
  • Room: Lecture hall
  • Host: Prof. Dr. Victor Sourjik
  • Contact: victor.sourjik@synmikro.mpi-marburg.mpg.de

Using microorganisms for bioremediation and metabolic engineering becomes popular in times of declining amounts of petroleum. Even though many organisms could be successfully engineered, a high metabolic burden and a lack of evolutionary stability remain. Therefore the usage of synthetic engineered microbial communities is under investigation as a potential solution. One challenge is the control of growth of each of the populations within the community. In order to balance the growth in a mixed synthetic E. coli community, we propose two growth-balancing systems: one is a quorum sensing system, the other one is a contact dependent inhibition system.

 
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