Dr. Ilka Bischofs-Pfeifer

Dr. Ilka Bischofs-Pfeifer

Complex Adaptive Traits (CATs)

Curriculum Vitae

2000 M.A. Physics, SUNY Stony Brook
2001 Diploma in Physics, University of Würzburg
2004 PhD in Theoretical Physics, University of Potsdam
2005-2008 Postdoc, UC Berkeley and Lawrence Berkeley National Laboratory
2009-2010 Postdoc, Zentrum für Molekulare Biologie Heidelberg (ZMBH)
2010 Emmy Noether Research Group Leader, University of Heidelberg
2011 ERC Starting Grant Principal Investigator
2016 Head of the Research Group “Complex Adaptive Traits (CATs)” at the MPI for Terrestrial Microbiology, Marburg, since 9/2016

Research area: Complex Adaptive Traits (CATs)

The Bischofs lab studies complex adaptive traits (CATs) of stressed bacteria. Our goals are to understand, to control and to engineer such traits. Using tools from molecular biology, microscopy and mathematical modelling we investigate how signaling networks regulate CATs. We seek to reveal fundamental organizing principles that relate the molecular network design to population-level behavior and vice versa. This should facilitate rational manipulations of bacterial populations and the implementation of novel functionalities into “smart” communities in the future.

Please visit also our website at the BioQuant of the University of Heidelberg.

Selected recent publications

A. Mutlu, S. Trauth, M. Ziesack, K. Nagler, J.-P. Bergeest, K. Rohr, N. Becker, T. Höfer and I.B. Bischofs (2018)
Phenotypic Memory in Bacillus subtilis links dormancy entry and exit by a spore quantity-quality tradeoff. Nature Communication 6: 69

H. Babel and I.B. Bischofs (2016)
Molecular and Cellular Factors Control Signal Transduction via Switchable Allosteric Modulator Proteins (SAMPs). BMC Systems Biology 10:35

D. Wolf, V. Rippa, J.C. Mobarec, P.Sauer, L. Adlung, P. Kolb and I. B. Bischofs (2016)
The quorum sensing regulator ComA from Bacillus subtilis activates transcription using topologically distinct DNA motifs. Nucleic Acids Research 44 (5), 2160-2172.

S. Pande, S. Shitut, L. Freund, M. Westermann, F. Bertels, C. Colesie, I. B. Bischofs and C. Kost (2015)
Metabolic cross-feeding via inter-cellular nanotubes among bacteria. Nature Communications 6: 6238

B. Drees, M. Reiger, K. Jung and I.B. Bischofs (2014)
A Modular View of the Diversity of Cell-Density-Encoding Schemes in Bacterial Quorum-Sensing Systems 
Biophysical Journal 107, 266-277

S. Trauth and I.B. Bischofs (2014)
Ectopic Integration Vectors for Generating Fluorescent Promoter Fusions in Bacillus subtilis with Minimal Dark Noise 
PLoS One 9(5) e98360

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