Supervised Theses

Doctoral theses      •     Master theses     •     Bachelor theses      


PhD theses

Patrick Gerlinger (2022)
Engineering the Synthetic Capabilities of a Modular Type I Polyketide Synthase

Christoph Diehl (2022)
Machine learning guided optimization of an artificial carbon dioxide fixation cycle and its extension towards value-added compounds

Richard McLean (2022)
In vitro Realisation of the Hydroxypropionyl-CoA/Acrylyl-CoA Cycle (Philipps-Universität Marburg)

Francesca Severi (2022)
New central carbon metabolic pathways in Alphaproteobacteria: from natural to synthetic metabolism (Philipps-Universität Marburg)

Kyra Geyer (2020)
Biochemical Characterization of the Phoslactomycin modular Polyketide Synthase (Philipps-Universität Marburg)

Simon Burgener (2020)
Expanding the repertoire of enzymatic C-C bond formation with one-carbon units (Philipps-Universität Marburg)

Tarryn Miller (2020)
Building a light driven synthetic carbon dioxide fixation cycle within micro-droplets (Philipps-Universität Marburg)

Iria Grundling (2020)
Propionyl-CoA synthase: Characterization, engineering and physiological role of a trifunctional fusion enzyme (Philipps-Universität Marburg)

Marieke Scheffen (2020)
Realization of a new-to-nature carboxylation pathway (Philipps-Universität Marburg)

Martina Carrillo Camacho (2020)
Implementation of CO2 fixation pathways into Methylorubrum extorquens AM1 (Philipps-Universität Marburg)

Gabriele Stoffel (2019)
Investigating and manipulating the reaction mechanism of reductive carboxylases (Philipps-Universität Marburg)

Bastian Vögeli (2018)
Control of reactive intermediates in enzymes and enzyme complexes (Philipps-Universität Marburg)

Thomas Schwander (2018)
The design and realization of synthetic pathways for the fixation of carbon dioxide in vitro (Philipps-Universität Marburg)

Lennart Schada von Borzyskowski (2016)
Exploring alternative solutions in the central carbon metabolism of Methylobacterium extorquens AM1 by metabolic engineering (ETH Zürich)

Dominik Peter (2016)
Substrate promiscuity, kinetics and engineering of enoyl-CoA carboxylases/reductases (ETH Zürich)


MSc theses

YoungJun Bae (2023)
Optimization of a synthetic carbon fixation cycle using machine learning (Friedrich-Schiller-Universität Jena)

Helena Schulz-Mirbach (2022)
Testing and optimizing a 3-hydroxypropionyl-CoA mutase in E. coli (Humboldt-Universität zu Berlin)

Nitin Bohra (2022)
Characterization of the Specificity of Aminotransferase Enzymes for Bottom-Up Assembly of in vitro Metabolic and Genetic Pathways

Antoine Raynal (2022)
A synthetic photorespiratory bypass in Chlamydomonas reinhardtii chloroplast (Evry University)

Hendrik Westedt (2022)
Engineering a Reductive Aldolase from Old Yellow Enzyme (Universität Basel)

Luca Brenker (2022)
Development and application of an in vitro biosensor platform based on a RNA aptamer reporter (Technische Universität Darmstadt)

Alina Schrodt (2022)
Establishment of an artificial endosymbiosis between Escherichia coli and Sachharomyces cerevisiae (Philipps-Universität Marburg)

Vanessa Göttfert (2021)
Integration of the 3-Hydroxypropionate bypass in E. coli – encoding glycolate assimilation on a synthetic chromosome (Heinrich-Heine-Universität Düsseldorf)

Katharina Happel (2021)
In vivo implementation of the tartronyl-CoA pathway in Pseudomonas putida (Goethe-Universität Frankfurt am Main)

Martin Schwalm (2020)
Directed evolution towards improved CO2 fixation of the multicatalytic propionyl-CoA synthase from Erythrobacter sp. NAP1 (Goethe-Universität Frankfurt am Main)

Celia Álvarez Fernández (2020)
Establishing the first module of a synthetic CO2 fixation pathway in Escherichia coli (Radboud University, Netherlands)

René Inckemann (2020)
Tool development for establishing Chlamydomonas reinhardtii as a chassis for synthetic CO2 fixation (Philipps-Universität Marburg)

Daniel Marchal (2019)
High-throughput enzyme engineering of a glycolyl-CoA carboxylase (Philipps-Universität Marburg)

Maren Nattermann (2019)
Neue Wege der C1-Assimilierung ausgehend von Formiat (Ruprecht-Karls-Universität Heidelberg)

Jana Senger (2019)
Enzymatic synthesis of meta-nitrophenol (Philipps-Universität Marburg)

Pascal Pfister (2018)
The photorespiratory 3-hydroxyproprionate bypass in Synechococcus elongatus PCC (Philipps-Universität Marburg)

Kristina Schell (2018)
(CO2) Fixing all problems! Directed evolution and rational engineering lead to improved carboxylase Ecr (Philipps-Universität Marburg)

Ole Schumann (2018)
Design and examination of riboswitches for Methylobacterium extorquens AM1 (Philipps-Universität Marburg)

Patrick Gerlinger (2017)
Understanding and altering the substrate specificity of the 6-deoxyerythronolide B synthase (Philipps-Universität Marburg)

Katharina Kremer (2017)
lnvestigation of acetate metabolism in Paracoccus denitrificans (Philipps-Universität Marburg)

Iria Bernhardsgrütter (2016)
Propionyl-CoA synthase - the key enzyme of a novel metabolic pathway in Erythrobacter sp. NAP1 (ETH Zürich)

Simon Burgener (2016)
Evolving methylsuccinyl-CoA dehydrogenase towards a proficient oxidase (ETH Zürich)

Sara Benkstein (2016)
Towards engineering of acyltransferase substrate specificity in the O-deoxyerythronolide B synthase (Philipps-Universität Marburg)



BSc theses

Laura Andreas (2022)
Implementierung eines CRISPRS/Cas Typ I-C Systems im Chloroplasten von Chlamydomonas reinhardtii (Philipps-Universität Marburg)

Lisa Theis (2022)
Characterization of a novel RamB transcription factor from Paracoccus denitrificans (Philipps-Universität Marburg)

Ramona Zülch (2022)
Characterization of a novel RamB transcription factor from Paracoccus denitrificans (Philipps-Universität Marburg)


Jonas Freudigmann (2021)
Construction of novel regulatory elements for the Chlamydomonas reinhardtii chloroplast (Philipps-Universität Marburg)

Michael Burgis (2021)

Roadmap for cyanobacteria engineering: Integration of a Fumaryl-CoA shunt in Synechococcus elongatus PCC 7942 (Philipps-Universität Marburg)

Felix Sippel (2019)
The β-hydroxyaspartate cycle: metabolic engineering and enzyme studies (Philipps-Universität Marburg)

Matthias Richter (2018)
Understanding dehydratase domains of the phoslactomycin synthase (Philipps-Universität Marburg)

Amelie Dransfeld (2018)
Untersuchung heterologer repABC-Regionen zur Anwendung in Methylobacterium extorquens AM1 (co-supervised with Prof. A. Becker, University of Marburg)

Jessica Lehmann (2018)
Engineering synthetic photorespiration: the Tartronyl-CoA Bypass (Philipps-Universität Marburg)

Luca Schulz (2018)
Biochemical Characterization of Pyruvate Formate-Lyase from different Microorganisms (Philipps-Universität Marburg)

Pascal Pfister (2016)
Optimizing the synthetic photorespiratory 3-hydroxypropionate bypass (Philipps-Universität Marburg)


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