Publications

Malay, A.D., Miyazaki ,N., Biela, A., Chakraborti, S., Majsterkiewicz, K., Stupka, I., Kaplan, C.S., Kowalczky, A.,  Piette, B.M.A, Hochberg, G.K.A., Wu, D., Wrobel , T.P., Fineber, A., Kuwask, M.S., Kelemen, M., Vavpetič, P., Pelicon, P., Kukura, P., Benesch, J.L.P., Iwasaki, Heddle, J.G. (2019)
An ultra-stable gold-coordinated protein cage displaying reversible assembly. Nature, 569, 438-442 DOI: 10.1038/s41586-019-1185-4

Santhanagopalan, I., Degiacomi, M.T., Shepherd, D.A., Hochberg, G.K.A., Benesch, J.L.P., Vierling, E. (2018)
It takes a dimer to tango: Oligomeric small heat-shock proteins dissociate to capture substrate. J.Biol.Chem., 293:19511-19521 DOI: 10.1074/jbc.RA118.005421

Hochberg G.K.A.*, Shepherd, D.A. *, Marklund, E.G. *, Santhanagoplan, I., Degiacomi, M.T., Laganowksy, A., Allison, T.M., Basha, E., Marty, M.T., Galpin, M.R., Struwe, W.B., Baldwin, A.J., Vierling, E., Benesch, J L.P. (2018)
Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions. Science (2018), 359: 930-935. F1000 recommended. DOI: 10.1126/science.aam7229

Siddiq, M.A., Hochberg, G.K.A., Thornton, J.W. (2017)
Evolution of protein specificity: Insights from ancestral protein reconstruction. Curr.Opin.Struc.Biol., 47:113-122. DOI: 10.1016/j.sbi.2017.07.003

Hochberg, G.K.A., Thornton, J.W. (2017)
Reconstructing Ancient Proteins to Understand the Causes of Structure and Function. Annu.Rev.Biophys., 22:  247-269. F1000 recommended. DOI: 10.1146/annurev-biophys-070816-033631

Marty, M.T., Baldwin, A.J., Marklund, E.G., Hochberg, G.K.A., Benesch, J.L.P., & Robinson, C.V., (2015)
Bayesian deconvolution of mass and ion mobility spectra: from binary interactions to polydisperse ensembles. Anal.Chem., 21: 4370-6. DOI: 10.1021/acs.analchem.5b00140

Hochberg, G.K.A & Benesch, J.L.P. (2014)
Dynamical structure of αB crystallin. Prog.Biophys. Mol.Biol., 115: 11-20. DOI: 10.1016/j.pbiomolbio.2014.03.003

Hochberg, G.K.A.*, Ecroyd, H.*, Liu, C., Cox, D., Cascio, D., Sawaya, M.R., Collier, M.P., Stroud, J., Carver, J.A., Baldwin, A.J., Robinson, C.V., Eisenberg, D., Benesch, J.L.P. & Laganowsky, A. (2014)
The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity, Proc. Natl. Acad. Sci. USA, 111: E1562-70. DOI: 10.1073/pnas.1322673111

Hilton, G.R., Hochberg, G.K.A., Laganowsky, A., McGinnigle, S.I., Baldwin, A.J., & Benesch, J.L.P. (2013)
C-terminal interactions mediate the quaternary dynamics of αB-crystallin. Phil. Trans. Roy. Soc. B., 368: 20110405. DOI: 10.1098/rstb.2011.0405

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