Special seminar

New techniques in ultra high throughput directed evolution screens

  • Date: Aug 10, 2018
  • Time: 14:00
  • Speaker: Dr. Raoul G. Rosenthal
  • Harvard University, John A. Paulson School of Engineering and Applied Sciences (SEAS), Cambridge MA, USA
  • Location: MPI for Terrestrial Microbiology
  • Room: Lecture hall
  • Host: Dr. Tobias Erb
  • Contact: toerb@mpi-marburg.mpg.de

Directed evolution is often limited by the throughput of selecting improved variants from libraries. We work on new microfluidic solutions to improve the selection throughput in directed evolution schemes of enzymes to >10e7 variants/day. In parallel we are working towards automated continuous evolution of enzymes to facilitate enzyme optimization for new reactions.

 
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