High-throughput interaction profiling in bacteria

Microbiology Seminar Series

  • Date: Jul 9, 2018
  • Time: 01:15 PM (Local Time Germany)
  • Speaker: Dr. Nassos Typas
  • European Molecular Biology Laboratory (EMBL), Heidelberg
  • Location: MPI for Terrestrial Microbiology
  • Room: Lecture hall
  • Host: Prof. Dr. Victor Sourjik
  • Contact: victor.sourjik@synmikro.mpi-marburg.mpg.de

Systematic and quantitative profiling of functional interactions at a genome-wide level provides unique insights into cellular behaviors and the underlying network architecture. In my lab, we have developed new tools and strategies for such systematic approaches in bacteria. Here, I will present recent developments on this front, and provide insights into how we use these approaches to uncover new biology in different bacterial species, and their interfaces with other microbes, the host and the environment. As highlights, I will zoom in a recent effort to identify general principles behind drug-drug interactions in bacteria, and present our advances in establishing experimental frameworks for high-throughput microbiomics.

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