Prof. Dr. Knut Drescher
Prof. Dr. Knut Drescher
Research Group Leader
Phone: +49 6421 28 21473

Research Group Members

Dr. Carey Nadell
Scientific Staff Member
Phone: +49 6421 28 21603
Dr. Praveen Singh
Postdoctoral Fellow
Dr. Stoyan Yordanov
Postdoctoral Fellow
Phone: +49 6421 28 21494
Fax: +49 6421 28 21402
Dr. Raimo Hartmann
Scientific Staff Member
Phone: +49 6421 28 21603
Lucia Vidakovic
Ph.D. Student
Phone: +49 6421 28 21603
Francisco Diaz Pascual
Ph.D. Student
Phone: +49 6421 28 21603

Prof. Dr. Knut Drescher - Bacterial Biofilms

Prof. Dr. Knut Drescher

Curriculum Vitae

Knut Drescher
Abitur, Altes Gymnasium Bremen, 2002
Master of Physics, University of Oxford, 2007
PhD (biophysics), DAMTP, University of Cambridge, 2010
Postdoc (biophysics), University of Cambridge, 2010-2011
Postdoc (molecular biology), Princeton University, 2011-2014
Head of the Max Planck Research Group "Bacterial Biofilms" at the MPI for Terrestrial Microbiology, Marburg, since 07/2014. 
Professor of Biophysics, Philipps-Universität Marburg, since 10/2015.

Research area: Bacterial Biofilms

The lab focuses on understanding collective bacterial behaviors, using biofilm formation as a model system. Bacterial biofilms are surface-associated bacterial communities that are held together by an extracellular matrix. Cells within these communities are highly resistant to antibiotics and display strong phenotypic heterogeneity. Using microscopy, molecular biology techniques, and mathematical modeling, we study how bacteria form these complex multicellular biofilm communities, and how biofilms affect bacterial ecology. 

Main lab website:

The group of Knut Drescher as per October 2015 Zoom Image
The group of Knut Drescher as per October 2015

Recent Selected Publications

C.D. Nadell, K. Drescher, K.R. Foster (2016) Spatial structure, cooperation, and competition in biofilms. Nature Reviews Microbiology 14, 589-600. (abstract)

K. Drescher, J. Dunkel, C.D. Nadell, S. van Teeffelen, I. Grnja, N.S. Wingreen, H.A. Stone, B.L. Bassler (2016) Architectural transitions in Vibrio cholerae biofilms at single-cell resolution. Proceedings of the National Academy of Sciences 113, E2066-E2072. (abstract) 

A. Persat, C.D. Nadell, K.M. Kim, F. Ingremeau, A. Siryaporn, K. Drescher, N.S. Wingreen, B.L. Bassler, Z. Gitai, H.A. Stone (2015) The mechanical world of bacteria. Cell 161, 988-997. (abstract) 

C.D. Nadell, K. Drescher, N.S. Wingreen, B.L. Bassler (2015) Extracellular matrix structure governs invasion resistance in bacterial biofilms. ISME Journal 9, 1700-1709. (abstract) 

K. Drescher, C.D. Nadell, H.A. Stone, N.S. Wingreen, B.L. Bassler (2014) Solutions to the public goods dilemma in bacterial biofilms. Current Biology 24, 50-55. (abstract) 

C.T. O'Loughlin, L.C. Miller, A. Siryaporn, K. Drescher, M.F. Semmelhack, B.L. Bassler (2013) A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proceedings of the National Academy of Sciences 110, 17981-17986. (abstract) 

K. Drescher, Y. Shen, B.L. Bassler, H.A. Stone (2013) Biofilm streamers cause catastrophic disruption of flow with consequences for environmental and medical systems. Proceedings of the National Academy of Sciences 110, 4345-4350. (abstract) 

C.D. Nadell, V. Bucci, K. Drescher, S.A. Levin, B.L. Bassler, J.B. Xavier (2013) Cutting through the complexity of cell collectives. Proceedings of the Royal Society B 280, 20122770. (abstract) 

K. Drescher, J. Dunkel, L.H. Cisneros, S. Ganguly, R.E. Goldstein (2011) Fluid dynamics and noise in bacterial cell-cell and cell-surface interactions. Proceedings of the National Academy of Sciences 108, 10940-10945. (abstract)

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