Prof. Dr. Knut Drescher
Abitur, Altes Gymnasium Bremen, 2002
Master of Physics, University of Oxford, 2007
PhD (biophysics), DAMTP, University of Cambridge, 2010
Postdoc (biophysics), University of Cambridge, 2010-2011
Postdoc (molecular biology), Princeton University, 2011-2014
Head of the Max Planck Research Group "Bacterial Biofilms" at the MPI for Terrestrial Microbiology, Marburg, since 07/2014.
Professor of Biophysics, Philipps-Universität Marburg, since 10/2015.
Research area: Bacterial Biofilms
The lab focuses on understanding collective bacterial behaviors, using biofilm formation as a model system. Bacterial biofilms are surface-associated bacterial communities that are held together by an extracellular matrix. Cells within these communities are highly resistant to antibiotics and display strong phenotypic heterogeneity. Using microscopy, molecular biology techniques, and mathematical modeling, we study how bacteria form these complex multicellular biofilm communities, and how biofilms affect bacterial ecology.
Main lab website:
Recent Selected Publications
C.D. Nadell, K. Drescher, K.R. Foster (2016) Spatial structure, cooperation, and competition in biofilms. Nature Reviews Microbiology 14, 589-600. (abstract)
K. Drescher, J. Dunkel, C.D. Nadell, S. van Teeffelen, I. Grnja, N.S. Wingreen, H.A. Stone, B.L. Bassler (2016) Architectural transitions in Vibrio cholerae biofilms at single-cell resolution. Proceedings of the National Academy of Sciences 113, E2066-E2072. (abstract)
A. Persat, C.D. Nadell, K.M. Kim, F. Ingremeau, A. Siryaporn, K. Drescher, N.S. Wingreen, B.L. Bassler, Z. Gitai, H.A. Stone (2015) The mechanical world of bacteria. Cell 161, 988-997. (abstract)
C.D. Nadell, K. Drescher, N.S. Wingreen, B.L. Bassler (2015) Extracellular matrix structure governs invasion resistance in bacterial biofilms. ISME Journal 9, 1700-1709. (abstract)
K. Drescher, C.D. Nadell, H.A. Stone, N.S. Wingreen, B.L. Bassler (2014) Solutions to the public goods dilemma in bacterial biofilms. Current Biology 24, 50-55. (abstract)
C.T. O'Loughlin, L.C. Miller, A. Siryaporn, K. Drescher, M.F. Semmelhack, B.L. Bassler (2013) A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proceedings of the National Academy of Sciences 110, 17981-17986. (abstract)
K. Drescher, Y. Shen, B.L. Bassler, H.A. Stone (2013) Biofilm streamers cause catastrophic disruption of flow with consequences for environmental and medical systems. Proceedings of the National Academy of Sciences 110, 4345-4350. (abstract)
C.D. Nadell, V. Bucci, K. Drescher, S.A. Levin, B.L. Bassler, J.B. Xavier (2013) Cutting through the complexity of cell collectives. Proceedings of the Royal Society B 280, 20122770. (abstract)
K. Drescher, J. Dunkel, L.H. Cisneros, S. Ganguly, R.E. Goldstein (2011) Fluid dynamics and noise in bacterial cell-cell and cell-surface interactions. Proceedings of the National Academy of Sciences 108, 10940-10945. (abstract)