Publications

2010-2005

Jain S, Kahnt J, van der Does C (2011)
Processing and maturation of the pilin of the type IV secretion system encoded within the gonococcal genetic island. J Biol Chem. 3;286(51):43601-10.
Ghosh A, Hartung S, van der Does C, Tainer JA, Albers SV. (2011)
Archaeal flagellar ATPase motor shows ATP-dependent hexameric assembly and activity stimulation by specific lipid binding.Biochem J. 2011 Jul 1;437(1):43-52.
Jain S, Mos'cicka KB, Bos MP, Pachulec E, Stuart MCA, Keegstra W, Boekema EJ, van der Does C (2011)
Structural Characterization of Outer Membrane Components of the Type IV Pili System in Pathogenic Neisseria. PLoS ONE 6(1): e16624.
Pachulec E, van der Does C (2010)
Conjugative plasmids of Neisseria gonorrhoeae. PLoS One. 5(4):e9962.
Pretz MG, van der Does C, Albers S-V, Schuurman-Wolters G, Driessen AJ (2008)
Structural stability of GlcV, the nucleotide binding domain of the glucose ABC transporter of Sulfolobus solfataricus, Biochim Biophys Acta. 1778(1):324-33.
Salgado-Pabón W, Jain S, Turner N, van der Does C, and Dillard JP, (2007)
Processing of chromosomal DNA for secretion by the Neisseria gonorrhoeae type IV secretion system, Mol Microbiol. 66(4):930-47.
Gompf S, Zutz A, Hofacker M, Haase A, van der Does C and Robert Tampé (2007)
Switching of the homooligomeric ABC transport complex MDL1 from posttranslational mitochondrial import to ER insertion, FEBS J. 74(20), 5298-310.
Hofacker, M., Gompf, S. Zutz, A., Presenti, C., Haase, W., van der Does, C., Model, K. and Tampé, R. (2006)
Structural and functional fingerprint of the mitochondrial ABC transporter MDL1 from Saccharomyces cerevisiae. J Biol Chem, 282(6):3951-61.
Pretz, M.G., Albers, S.V., Schuurman-Wolters, G., Tampe, R., Driessen, A.J.M., and van der Does, C. (2006)
Thermodynamics of the ATPase cycle of GlcV, the nucleotide-binding domain of the glucose ABC transporter of Sulfolobus solfataricus, Biochemistry, 45(50), 15056-15067
Van der Sluis, E.O., Nouwen, N., Koch, J., de Keyzer, J., Van der Does, C. and Tampé, R., and Driessen, A.J.M. (2006)
Identification of two interaction sites in SecY that are important for the functional interaction with SecA. J Mol Biol. 361(5), 839-49.
van der Does, C., Presenti, C., Schulze, K., Dinkelaker, S., Tampé, R. (2006)
Kinetics of the ATP hydrolysis cycle of the nucleotide-binding domain of MDL1 studied by a novel site-specific labeling technique, J Biol Chem, 281(9), 5694-701.
Scheuring, J., Braun, N., Nothdurft, L., Stumpf, M., Veenendaal, A.K., Kol, S., van der Does, C., Driessen, A.J.M., and Weinkauf, S. (2005)
The oligomeric distribution of SecYEG is altered by SecA and translocation ligands, J Mol Biol. 25;354, 258-71.
de Keyzer, J., van der Sluis, E.O., Spelbrink, R.E., Nijstad, N., de Kruijff, B., Nouwen, N., van der Does, C., Driessen, A.J.M. (2005)
Covalently Dimerized SecA Is Functional in Protein Translocation, J Biol Chem. 280, 35255-60.
Plantinga, T.H., van der Does C., Tomkiewicz, D., van Keulen, G., Konings, W.N., and Driessen, A.J.M. (2005)
Deletion of the yiaMNO transporter genes affects the growth characteristics of Escherichia coli K-12. Microbiology, 151, 1683-1689.
Natale, P., den Blaauwen, T., van der Does, C., Driessen, A.J.M. (2005)
Conformational state of the SecYEG-bound SecA probed by single tryptophan fluorescence spectroscopy. Biochemistry. 44. 6424-6432.

2004-2000

Natale, P., Swaving, J., van der Does, C., De Keyzer, J., and Driessen, A.J.M. (2004)
Binding of SecA to the SecYEG complex accelerates the nucleotide exchange kinetics on SecA, J Biol Chem. 279, 13769-13777.
Plantinga, T.H., van der Does, C., and Driessen, A.J.M. (2004)
Transporters evolution and carbohydrate metabolic clusters, Trends Microbiol. 12, 4-7.
Plantinga, T.H., van der Does, C., Badia, J., Aguilar, J., Konings, W.N., and Driessen, A.J.M. (2004)
Functional characterization of the Escherichia coli K-12 yiaMNO transport protein genes, Mol Membr Biol. 21, 51-7.
Van der Does, C. and Tampé, R. (2004)
Changing orders - primary and secondary membrane transporters revised, ChemBiochem. 6, 1171-1175.
Van der Does, C. and Tampé, R. (2004)
How do ABC transporters drive transport? Biological Chemistry, 5, 927-33.
Veenendaal, A.K.J., van der Does, C., and Driessen, A.J.M. (2004)
The Protein-Conducting Channel, Biochim Biophys Acta, Molecular Cell Research, 1;1694(1-3):81-95.
Janas, E., Hofacker, M., Chen, M., Gompf, S., van der Does, C., and Tampé, R (2003)
The ATP hydrolysis cycle of the nucleotide-binding domain of the mitochondrial ATP-binding cassette transporter Mdl1p. J Biol Chem. 278, 26862-26869.
Van der Does, C., de Keyzer, J., van der Laan, M., and Driessen, A.J.M. (2003)
Reconstitution of the Purified Bacterial Protein Translocase. Methods Enzymol. 372, 86-98.
De Keyzer, J., van der Does, C., Kloosterman, T.G., and Driessen, A.J.M. (2003)
Direct demonstration of ATP-dependent release of SecA from a translocating preprotein by surface plasmon resonance. J Biol Chem. 278, 29581-29586.
Curley, P., van der Does, C., Driessen, A.J.M., Kok, J., and Van Sinderen, D. (2003)
Purification and characterisation of a lactococcal aminoacylase. Arch Microbiol. 179, 402-408.
De Keyzer, J., van der Does, C. and Driessen, A.J.M. (2003)
Kinetic analysis of the translocation of fluorescent precursor proteins into Escherichia coli membrane vesicles. J Biol Chem. 277, 46059-46065.
De Keyzer, J., van der Does, C., and Driessen, A.J,M. (2003)
The bacterial translocase: a dynamic protein channel complex, Cell Mol Life Sci. 60, 2034-2053.
Van der Does, C., Nouwen, N., and Driessen, A.J.M. (2003)
The SEC translocase. In: Protein Secretion Pathways in Bacteria. Ed. B. Oudega. Kluwer Press, Amsterdam, 23-50.
Veenendaal, A.K.J., van der Does, C., and Driessen, A.J.M. (2002)
The core of the bacterial translocase harbors a titlted transmembrane segment 3 of SecE. J Biol Chem. 277, 36640-36645.
De Keyzer, J., van der Does, C., Swaving J., and Driessen, A.J.M (2002)
The F286Y mutation of PrlA4 tempers the signal sequence suppressor phenotype by reducing the SecA binding affinity. FEBS Lett. 510, 17-21.
Veenendaal, A.K.J., van der Does, C., and Driessen, A.J.M. (2002)
The core of the bacterial translocase harbors a titlted transmembrane segment 3 of SecE. J Biol Chem. 277, 36640-36645.
De Keyzer, J., van der Does, C., Swaving J., and Driessen, A.J.M (2002)
The F286Y mutation of PrlA4 tempers the signal sequence suppressor phenotype by reducing the SecA binding affinity. FEBS Lett. 510, 17-21.
Driessen, A.J.M., Nouwen, N., and van der Does, C. (2002)
Bacterial Protein Secretion and Targeting. Biopolymers, Volume 7, Polyamides and Complex Proteinaceous Materials I, Eds. S. Fahnestock and A. Steinbüchel. Wiley-VCH, New York, 227-259.
Driessen, A.J.M. and van der Does, C. (2002)
Protein Export in Bacteria: Protein Targeting, Transport and Translocation. Eds. R. Dalbey and G. von Heijne. Chapter 4, Academic Press, 47-73.
Veenendaal, A.K.J., van der Does, C., and Driessen, A.J.M (2001)
Mapping the sites of interaction between SecY and SecE by cysteine scanning mutagenesis. J Biol Chem.276, 32559-32566.
Driessen, A.J.M., Manting, E.H., and van der Does, C. (2001)
The structural basis of protein targeting and translocation in bacteria. Nat Struct Biol. 8, 492-498.
Manting, E.H., van der Does, C., Remigy, H., Engel, A., and Driessen, A.J.M. (2000)
SecYEG assembles into a tetramer to form the active protein translocation channel. EMBO J. 19, 852-861.
Scotti, P.A., Urbanus, M.L., Brunner, J., de Gier, J.W., von Heijne, G., van der Does, C., Driessen, A.J.M., Oudega, B., and Luirink, J. (2000)
YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase. EMBO J. 19, 542-549.
Van der Does, C., Swaving, J., van Klompenburg, W., and Driessen, A.J.M. (2000)
Non-bilayer lipids stimulate the activity of the reconstituted bacterial protein translocase. J. Biol. Chem. 275, 2472-2478.

1999-1993

Den Blaauwen, T., van der Wolk, J.P.W., van der Does, C., van Wely, K.H.M., and Driessen, A.J.M. (1999)
Thermodynamics of nucleotide binding to NBS-I of the Bacillus subtilis preprotein translocase subunit SecA. FEBS Lett. 458, 145-150.
Kaufmann, A., Manting, E.H., Veenendaal, A.K.J., Driessen, A.J.M., and van der Does, C. (1999)
Cysteine-directed cross-linking demonstrates that helix 3 of SecE is close to helix 2 of SecY and helix 3 of a neighboring secE. Biochemistry 38, 9115-9125.
Manting, E.H., Kaufmann, A., van der Does, C., and Driessen, A.J.M. (1999)
A Single Amino Acid Substitution in SecY Stabilizes the Interaction with SecA. J. Biol. Chem. 274, 23868-23874.
Van de Vossenberg, J.L., Albers, S.-V., van der Does, C. and Driessen, A.J.M., and van Klompenburg, W. (1998)
The positive inside rule is not determined by the polarity of the delta psi. Mol. Microbiol. 29, 1125-1127.
Van der Does, C., Manting, E.H., Kaufmann, A., Lutz, M., and Driessen, A.J.M. (1998)
Interaction between SecA and SecYEG in micellar solution and formation of the membrane-inserted state. Biochemistry 37, 201-210.
Van Voorst, F., van der Does, C., Brunner, J., Driessen, A.J.M., and de Kruijff, B. (1998)
Translocase-bound SecA is largely shielded from the phospholipid acyl chains. Biochemistry 37, 12261-12268.
Fekkes, P., van der Does, C., and Driessen, A.J.M. (1997)
The molecular chaperone SecB is released from the carboxy- terminus of SecA during initiation of precursor protein translocation. EMBO J. 16, 6105-6113.
Manting, E.H., van der Does, C., and Driessen, A.J.M. (1997)
In vivo cross-linking of the SecA and SecY subunits of the Escherichia coli preprotein translocase. J. Bacteriol. 179, 5699-5704.
Den Blaauwen, T., de Wit, J.G., Gosker, H., van der Does, C., Breukink, E.J., de Leij, L., and Driessen, A.J.M. (1997)
Inhibition of preprotein translocation and reversion of the membrane inserted state of SecA by a carboxyl terminus binding mAb. Biochemistry 36, 9159-9168.
Van der Does, C., den Blaauwen, T., de Wit, J.G., Manting, E.H., Groot, N.A., Fekkes, P., and Driessen, A.J.M. (1996)
SecA is an intrinsic subunit of the Escherichia coli preprotein translocase and exposes its carboxyl terminus to the periplasm. Mol. Microbiol. 22, 619-629.
Poolman, B., Knol, J., van der Does, C., Henderson, P.J., Liang, W.J., Leblanc, G., Pourcher, T., and Mus-Veteau, I. (1996)
Cation and sugar selectivity determinants in a novel family of transport proteins. Mol. Microbiol. 19, 911-922.
Balandin, T., van der Does, C., Albert, J.M., Bol, J.F., and Linthorst, H.J. (1995).
Structure and induction pattern of a novel proteinase inhibitor class II gene of tobacco. Plant Mol.Biol. 27, 1197-1204.
Driessen, A.J.M., de Wit, J.G., Kuiper, W., Van der Wolk, J.P., Fekkes, P., van der Does, C., van Wely, K.H.M., Manting, E.H., and den Blaauwen, T. (1995)
SecA, a novel ATPase that converts chemical energy into a mechanical force to drive precursor protein translocation. Biochem. Soc. Trans. 23, 981-985.5.
Linthorst, H.J., van der Does, C., Brederode, F.T., and Bol, J.F. (1993)
Circadian expression and induction by wounding of tobacco genes for cysteine proteinase. Plant Mol.Biol. 21, 685-694.
Linthorst, H.J., van der Does, C., van Kan, J.A., and Bol, J.F. (1993)
Nucleotide sequence of a cDNA clone encoding tomato (Lycopersicon esculentum) cysteine proteinase. Plant Physiol. 101, 705-706.
Linthorst, H.J., Brederode, F.T., van der Does, C., and Bol, J.F. (1993)
Tobacco proteinase inhibitor I genes are locally, but not systemically induced by stress. Plant Mol.Biol. 21, 985-992.