Chris van der Does
Dr. Chris van der Does
MPI für terrestrische Mikrobiologie
Karl-von-Frisch-Straße 10
D-35043 Marburg / Germany
Phone: +49 6421 178-303
Fax: +49 6421 178-309
Email: does@mpi-marburg.mpg.de
Research group members
Group Leader: Dr. Chris van der Does
Graduate students: Eva-Maria Heller, Katja Siewering, Maria Zweig
Undergraduate students: Susan Lopez-Röhle
Master students: Tobias Deinzer, Sabine Schork
Technical assistant: Jürgen Koch
Dr. Chris van der Does
Curriculum Vitae
Chris van der Does (born 1967)
MSc (Chemistry), University of Leiden, 1993
PhD, University of Groningen (molecular microbiology),1993 - 1998
Short term EMBO fellowship, University of Basel (M. E. Müller-Institute for Microscopy), 1998
Post-doc, University of Groningen (molecular microbiology), 1999 - 2002
Post doc , University of Frankfurt, (institute of biochemistry), 2002-2005
Tenure-Track Assistant professor (molecular microbiology), University of Groningen, 2005-2008
Group Leader in the Department of Ecophysiology at the MPI for Terrestrial Microbiology, since 10/2008
Research Area: Type IV secretion in Neisseria gonorrhoeae
Type IV secretion systems (T4SS) are used by Gram-negative bacteria to deliver macromolecular substrates to target cells. These target cells can be other bacteria to which DNA is transferred, but also eukaryotic cells to which oncogenic DNA or effector proteins are transported. The spread of DNA between bacterial species via T4SSs is one of the major causes of the rapid spread of antibiotic resistance, a problem, confronting communities and nations worldwide.
More about "Type IV secretion in Neisseria gonorrhoeae"
Recent publications
Pretz MG, van der Does C, Albers S-V, Schuurman-Wolters G, Driessen AJ (2007) Structural stability of GlcV, the nucleotide binding domain of the glucose ABC transporter of Sulfolobus solfataricus, Biochim Biophys Acta. 1778(1):324-33.
Salgado-Pabón W, Jain S, Turner N, van der Does C, and Dillard JP, (2007) Processing of chromosomal DNA for secretion by the Neisseria gonorrhoeae type IV secretion system, Mol Microbiol. 66(4):930-47.
Gompf S, Zutz A, Hofacker M, Haase A, van der Does C and Robert Tampé (2007) Switching of the homooligomeric ABC transport complex MDL1 from posttranslational mitochondrial import to ER insertion, FEBS J. 74(20), 5298-310.