Lotte Sogaard-Andersen
Prof. Dr. Lotte Søgaard-Andersen
MPI für terrestrische Mikrobiologie
Karl-von-Frisch-Straße 10
D-35043 Marburg / Germany
Phone: +49 6421 178201
Fax: +49 6421 178209
Email:
sogaard@mpi-marburg.mpg.de
Research group members
Group leader: Prof. Dr. Lotte Søgaard-Andersen
Lab-Manager: Susanne Kneip
Scientific staff members: Dr. Stuart Huntley, Dr. Anke Treuner-Lange, Dr. Kristin Wuichet
Guest: Prof. Dr. Peter Lenz (Faculty of Physics, Philipps-Universität)
Postdoctoral Fellows: Dr. Iryna Bulyha, Dr. Anna Konovalova, Dr. Nuria Gomez Santos
PhD students: Edina Hot, Beata Jakobczak, Shuxin Jia (guest), Daniela Keilberg, Tobias Petters, Carmen Schmidt, Dominik Schumacher, Dorota Skotnicka
BSc/MSc students: Dominik Beuter, Ina Binzen, Florian Drescher, Stephanie Löbach, Nicolle Som
Technical assistants: Andrea Harms, Jörg Kahnt, Steffi Lindow, Elisabeth Ried
IT: Dr. Manfred Irmler
Prof. Dr. Lotte Søgaard-Andersen
Curriculum Vitae
Lotte Søgaard-Andersen (born 1959)
M. Sc. thesis (Molecular biology), University of Odense, 1984
Medical Doctor, University of Odense, 1988
Visiting scientist, Institut Pasteur, Paris, 1990
PhD (Molecular biology), University of Odense, 1991
Post-doc, University of Odense, 1991
Assistant professor, University of Odense, 1992
Visiting scientist, Stanford University, 1994
Associate professor, University of Southern Denmark, 1996
Professor, University of Southern Denmark, 2002
Director and Head of the Department of Ecophysiology at the MPI in Marburg, since 2004
Professor for Microbiology at the Philipps-Universität Marburg, since 2008
Group leaders at the department
Dr. Penelope Higgs
Dr. Kai Thormann
Dr. Chris van der Does
Research area: Bacterial development and differentiation
Bacterial cells process vast amounts of information to generate and regulate sophisticated output responses such as adaptation, differentiation, growth and cell movement. In our research we pursue two overall aims: Firstly, we aim to understand how bacteria process information to generate appropriate output responses. Secondly, we aim to understand how molecular machines involved in motility and cell division and how their activity is regulated.
Information processing is carried out by complex networks of signal transduction proteins. A challenging problem in biology is to understand how these protein networks are organized in space and time to allow the ordered execution of these various tasks. We are probing this question by studying signal transduction pathways and networks governing development, motility, cell polarity, and cell cycle in Myxococcus xanthus.
More about "Bacterial development and differentiation"
Recent publications
Petters, T., Zhang, X., Nesper, J., Treuner-Lange, A., Gomez-Santos, N., Hoppert, M., Jenal, U. & Søgaard-Andersen, L. (2012) The orphan histidine protein kinase SgmT is a c-di-GMP receptor and regulates composition of the extracellular matrix together with the orphan DNA binding response regulator DigR in Myxococcus xanthus. Mol. Microbiol. 84, 147-165.
Konovalova, A., Löbach. S. & Søgaard-Andersen, L. (2012) A RelA-dependent two-tiered regulated proteolysis cascade controls synthesis of a contact-dependent intercellular signal in Myxococcus xanthus. Mol. Microbiol. 84, 260-275.
Peruani, F., Starruß, J., Jakovljevic, V., Søgaard-Andersen, L., Bär, M. & Deutsch, A. (2012) Collective motion and nonequilibrium cluster formation in colonies of gliding bacteria. Phys. Rev. Lett. 108, 098102.
Bulyha, I., Hot, E., Huntley, S. & Søgaard-Andersen, L. (2011)
GTPases in bacterial cell polarity and signalling. Curr. Opin. Microbiol. 14, 726-733.
Miertzschke M., Koerner C., Vetter I.R., Keilberg D., Hot E., Leonardy S., Søgaard-Andersen L. & Wittinghofer A. (2011) Mechanistic insights into bacterial polarity from structural analysis of the Ras-like G protein MglA and its cognate GAP MglB. EMBO J. 30, 4185-4197.
Lenz, P. & Søgaard-Andersen, L. (2011) Temporal and spatial oscillations in bacteria. Nat. Rev. Microbiol. 9,565-577.
Leonardy, S., Miertzschke, M., Bulyha, I., Sperling, E., Wittinghofer, A. & Søgaard-Andersen, L. (2010) Regulation of dynamic polarity switching in bacteria by a Ras-like G-protein and its cognate GAP. EMBO J. 29, 2276-2289.