Chris van der Does
Dr. Chris van der Does
MPI für terrestrische Mikrobiologie
Karl-von-Frisch-Straße 10
D-35043 Marburg / Germany
Phone: +49 6421 178-303
Fax: +49 6421 178-309
Email: does@mpi-marburg.mpg.de
Research group members
Group leader: Dr. Chris van der Does
Graduate Students:Maria Zweig, Eva-Maria Heller, Katja Siewering
Undergraduate student: Stephan Rempel
Technical assistant: Jürgen Koch
Dr. Chris van der Does
Curriculum Vitae
Chris van der Does (born 1967)
MSc (Chemistry), University of Leiden, 1993
PhD, University of Groningen (molecular microbiology),1993 - 1998
Short term EMBO fellowship, University of Basel (M. E. Müller-Institute for Microscopy), 1998
Post-doc, University of Groningen (molecular microbiology), 1999 - 2002
Post doc , University of Frankfurt, (institute of biochemistry), 2002-2005
Tenure-Track Assistant professor (molecular microbiology), University of Groningen, 2005-2008
Group Leader in the Department of Ecophysiology at the MPI for Terrestrial Microbiology, since 10/2008
Research Area: Type IV secretion in Neisseria gonorrhoeae
Type IV secretion systems (T4SS) are used by Gram-negative bacteria to deliver macromolecular substrates to target cells. These target cells can be other bacteria to which DNA is transferred, but also eukaryotic cells to which oncogenic DNA or effector proteins are transported. The spread of DNA between bacterial species via T4SSs is one of the major causes of the rapid spread of antibiotic resistance, a problem, confronting communities and nations worldwide.
More about "Type IV secretion in Neisseria gonorrhoeae"
Recent publications
Jain S, Kahnt J, van der Does C (2011) Processing and maturation of the pilin of the type IV secretion system encoded within the gonococcal genetic island J Biol Chem. 3;286(51):43601-10.
Ghosh A, Hartung S, van der Does C, Tainer JA, Albers SV (2011) Archaeal flagellar ATPase motor shows ATP-dependent hexameric assembly and activity stimulation by specific lipid binding Biochem J. 437(1):43-52.
Jain S, Moscicka KB, Bos MP, Pachulec E, Stuart MC, Keegstra W, Boekema EJ, van der Does C. (2011) Structural characterization of outer membrane components of the type IV pili system in pathogenic Neisseria. PLoS One. 6(1):e16624.
Pachulec E, van der Does C. (2010) Conjugative plasmids of Neisseria gonorrhoeae, PLoS One. 1;5(4):e9962.